syngo DynaCT Cardiac Paravalvular Mitral Valve Leakage

Samir Kapadia, Heart and Vascular Institute Cleveland


November 21, 2011
Figure 3: syngo DynaCT Cardiac with syngo iGuide Toolbox markers indicating the positions of the paravalvular leaks from TEE.

Patient History
72-year-old, male patient with previously placed bioprosthetic mitral valve.

Mitral regurgitation (grade 3+) due to periprosthetic leak (Video 1). To view the videos click here.

Closure of the paravalvular leak with an 8 mm VSD closure device under TEE (transesophageal echo) and fluoroscopic guidance. syngo iGuide Toolbox graphics were overlaid as additional guidance.

The case demonstrated that the overlay of 3-D information on the live fluoroscopic images provided additional helpful information.

 More detailed information can be found in the following publication:
 Krishnaswamy A, Tuzcu EM, Kapadia S. "Three-dimensional computed tomography in the cardiac catheterization laboratory." Catheter Cardiovasc Interv. 2010

Detailed Workflow Description
Pre-procedural cardiac CT data was retrieved from the PACS. (Video 2) The following structures were marked with syngo iGuide Toolbox graphics:
    •    Mitral valve plane
    •    Positions of the paravalvular leaks (based on the information of the diagnostic TEE Picture 3 )
    •    Aortic valve plane (Picture 4)
    •    Area for transseptal puncture (Picture 5)

The patient was positioned on the table with arms up to match the patient’s position during the pre-procedural cardiac CT. Arms were kept up during the whole procedure. A five-second syngo DynaCT Cardiac run was performed without contrast (Video 6). During this rotational acquisition a pigtail catheter was positioned in the aortic root to visualize the position of the aorta and the aortic root as landmarks for the syngo InSpace 3-D/3-D registration. Patient was asked just to hold his breath, i.e., no deep inspiration or expiration in order to be in a similar breathing situation as during the remaining procedure. This helps increasing the overlay accuracy.

 3-D/3-D registration of syngo DynaCT Cardiac image and CT was performed in syngo InSpace with the pigtail catheter and the mitral valve serving as landmarks. (Video 7).

The overlaid 3-D markers helped as additional guidance during the procedure for:
    •    a) the puncture of the atrial septum
    •    b) the progression of a guidewire through a leak (Video 8)
    •    c) the adjustment of the closure devices (Video 9)


  • Figure 4: syngo DynaCT Cardiac with syngo iGuide Toolbox markers indicating the plane of the aortic valve.
  • Figure 5: syngo DynaCT Cardiac with syngo iGuide Toolbox markers indicating the desired region of the transseptal puncture.