Siemens Symbia Intevo Fully Integrates SPECT and CT Imaging

World’s first xSPECT system completely integrates SPECT and CT


September 9, 2013
xSPECT, SPECT/CT, Siemens Intevo
A comparison showing standard SPECT/CT imaging (left) and the much clearer xSPECT imaging that combines the image data from the two modalities for improved quality.

Siemens’ Symbia Intevo is the first system to completely integrate high sensitivity of single-photon emission computed tomography (SPECT) with the high specificity of computed tomography (CT) into a single modality, rather than imaging as separate overlay images. Siemens is calling the combined imaging modality technology xSPECT.  It completely integrates data from both modalities, Symbia Intevo generates high resolution and, for the first time, quantitative images.  Higher Resolution Frame of Reference
In conventional SPECT/CT imaging, the SPECT image has always been reconstructed using SPECT's low-fidelity frame of reference. For this reason, the CT resolution has been downgraded dramatically to the level of SPECT to enable the mechanical fusion of both datasets. Siemens’ new xSPECT modality reconstructs both the SPECT and CT portions of the image using the high CT frame of reference for precise, accurate alignment that facilitates the extraction and deep integration of medically relevant information. This ability is also the basis for differentiating between tissue boundaries in bone imaging. With the xSPECT Bone feature, physicians can provide additional support for detection and distinguishing between cancerous lesions and degenerative disorders. Quantitative SPECT
Symbia Intevo’s precise alignment of SPECT and CT provides physicians with essential volumetric information from the CT scan, enabling accurate, consistent and reproducible quantification, a numerical indication of a tumor’s level of metabolic activity. With the xSPECT Quant feature, the physician can apply quantitative information to aid in the assessment whether a patient's course of treatment has regressed, stabilized or grown, an assessment that is difficult to make with a purely visual assessment of the tumor. Reduced CT Dose
While Symbia Intevo uses more CT data than previous systems, Siemens is still able to limit patient dose by offering combined applications to reduce exposure (CARE). Unique to Siemens, these applications include the CARE Dose4D technique, which can reduce patient CT radiation dose by up to 68 percent. Increased Productivity, Throughput
Symbia Intevo also offers applications to improve productivity and patient throughput. For example, Siemens’ Autoform collimator captures up to 26 percent more counts, or photons that are generated from radiotracer activity as compared to conventional collimators. This increased number of counts potentially reduces image acquisition time for increased patient throughput. The U.S. Food and Drug Administration (FDA) has granted 510(k) market clearance for Siemens’ Symbia Intevo in September 2013. For more information:

  • The Symbia Intevo system when it was unveiled in June at the Society of Nuclear Medicine and Molecular Imaging (SNMMI).