News

April 1, 2011 –Results from the RADAR Phase 2b clinical trial will be announced at the i2 Summit during the American College of Cardiology (ACC) 2011 Annual Scientific Session and Expo. The trial...

March 30, 2011 – Interventional radiologists have completed the first human randomized controlled trial of therapeutic renal denervation, or RDN. RDN is a procedure that uses a catheter-based...

March 25, 2011 – The American College of Cardiology (ACC) and the American Heart Association (AHA) have released a focused update to the 2007 guidelines for the managing patients with unstable...

March 18, 2011 – Researchers have found a link between high blood pressure and a greater drop in average walking speeds in older adults, according to results from a new study. The drop seems to...

March 11, 2011 – Sildenafil, a drug used to treat erectile dysfunction and pulmonary hypertension, has another possible use – helping children and young adults with congenital heart disease to...

March 10, 2011 – New guidelines have been published in The Annals of Thoracic Surgery that include point-of-care testing for platelet reactivity as a new recommendation for...

March 8, 2011 – Nile Therapeutics is pursuing a new indication for cenderitide, formerly CD-NP. The company is looking to develop the drug as an outpatient therapy to be delivered to acutely...

March 8, 2011 – The U.S. Food and Drug Administration (FDA) announced monthly liver enzyme tests are no longer required for those taking Letairis tablets (ambrisentan), made by Gilead Sciences....

March 7, 2011 – Massachusetts General Hospital (MGH) has granted an exclusive license to Santaris Pharma A/S for intellectual property related to the regulation of microRNA for the treatment of...

March 7, 2011 – Nile Therapeutics will partner with Medtronic to develop natriuretic peptide, cenderitide, formerly CD-NP, for heart failure and renal disease applications.

March 1, 2011 – The U.S. Food and Drug Administration (FDA) approved azilsartan medoxomil to treat high blood pressure (hypertension) in adults. Azilsartan medoxomil, also known as Edarbi, is made...

March 1, 2011 – A new study assessing the utility of genetic testing to determine a personalized warfarin dose for individual patients has begun at Overlake Hospital Medical Center in Bellevue,...

February 24, 2011 – Upsher-Smith Laboratories, is voluntarily recalling one lot (lot #284081) of Jantoven Warfarin Sodium, USP, 3 mg tablets, an anticoagulant with an expiration date of September...

February 16, 2011 – The newly approved drug dabigatran is an alternative to warfarin to help prevent dangerous blood clots in patients with atrial fibrillation, according to updated guidelines...

February 10, 2011 – A Phase 2 clinical trial has been initiated to test the safety and efficacy of drug to reverse heparin in patients undergoing percutaneous coronary intervention (PCI). The...

January 7, 2011 – A new study from The Ohio State University found that Protandim can suppress intimal hyperplasia, the over-proliferation of cells that line the walls of blood vessels. The...

December 29, 2010 - Research on reducing risks, improving medical treatment and improving lifestyle behaviors to fight the battle against heart disease and stroke are among the key scientific...

December 29, 2010 – Patient enrollment has been completed for a Phase III trial of an oral Factor Xa inhibitor. The ENGAGE AF-TIMI 48 study will investigate edoxaban, by Daiichi Sankyo, for...

December 27, 2010 – The U.S. Food and Drug Administration (FDA) approved Amturnide (aliskiren, amlodipine and hydrochlorothiazide) tablets for the treatment of high blood pressure. It combines the...

December 21, 2010 – A once-daily, three-in-one combination blood pressure treatment has been approved in Germany. Sevikar HCT, from Daiichi Sankyo Europe, combines olmesartan medoxomil, amlodipine...

December 17, 2010 – Data published in Circulation: Cardiovascular Interventions showed that a protein used with coronary stents significantly reduced two key biomarkers of cardiac...

December 17, 2010 - The U.S. Food and Drug Administration (FDA) has requested additional analyses of the trial data in its review of the new antiplatelet agent ticagrelor (Brilinta).

December 15, 2010 – A guest editorial in the new publication Clinical Investigation highlights dabigatran etexilate as an alternative to warfarin for long-term stroke prevention in...

December 13, 2010 – Based on emerging safety information, the pulmonary arterial hypertension (PAH) drug sitaxentan is being voluntarily withdrawn from the market. Pfizer is also discontinuing...

November 24, 2010 – Cardiologists and primary care physicians now perceive AstraZeneca's Crestor as comparable to Pfizer’s Lipitor in treating and reducing mortality in dyslipidemia patients,...

November 22, 2010 – Data presented at the American Heart Association’s Scientific Sessions 2010 showed that percutaneous renal nerve ablation reduces blood pressure. The data, which was also...

November 18, 2010 – In the trial of 1,623 patients with coronary heart disease (CHD) or CHD risk equivalents, an investigational CETP inhibitor showed no significant differences from placebo in...

November 17, 2010 – Chronic heart failure patients treated with eplerenone (Inspra) experienced a significant reduction in risk of cardiovascular death or heart failure hospitalizations. The data...

November 17, 2010 - Results from the GRAVITAS Trial found that doubling the maintenance dose of clopidogrel (Plavix) did not reduce the risk of further ischemic events after percutaneous coronary...

November 16, 2010 – Results from the ROCKET AF trial showed that rivaroxaban given once daily is superior at reducing stroke and non-central nervous system (CNS) systemic embolism in patients with...

November 8, 2010 – The American College of Cardiology (ACC) and American Heart Association (AHA) issued a joint report outlining new performance measures in cardiac care. The full report will be...

October 25, 2010 - A post-hoc-analysis from JUPITER, published in the European Heart Journal, shows rosuvastatin (Crestor) significantly reduced major cardiovascular (CV) events,...

October 25, 2010 – A new study shows that an intensive population management program that matches heart disease patients to personal nurses and clinical pharmacy specialists not only reduces the...

October 20, 2010 - The U.S. Food and Drug Administration (FDA) approved a new drug to help prevent stroke and blood clots in patients with abnormal heart rhythm (atrial fibrillation). Pradaxa (...

October 15, 2010 – The U.S. Food and Drug Administration (FDA) has approved an abbreviated new drug application (ANDA) for a generic equivalent to Novartis’ Lotrel capsules.

October 13, 2010 – A recall was issued for bottles of 40 mg Lipitor, due to a small number of reports of an uncharacteristic odor related to the packaging.

A medical assessment has...

October 13, 2010 – The anti-obesity drug sibutramine will be withdrawn from the U.S. market after a study found it had cardiovascular safety risks. Sibutramine (Meridia), made by Abbott, is a...

October 8, 2010 – New data from the HORIZONS-AMI trial shows that administering the anticoagulant bivalirudin (Angiomax) enhances survival in heart attack patients undergoing angioplasty after...

October 7, 2010 - Taking medication at night instead of in the morning significantly increases efficacy in keeping blood pressure within a healthy range, according to a new study in ...

October 4, 2010 – The U.S. Food and Drug Administration (FDA) Cardiovascular and Renal Drugs Advisory Committee voted 9 to 0 in favor of approving dabigatran etexilate for stroke prevention in...

September 29, 2010 - Preclinical data of a therapy designed to treat drug-resistant hypertension was presented last week at the Transcatheter Cardiovascular Therapeutics (TCT) 2010 symposium in...

September 24, 2010 - Trial data have established the safety of a reversible PAR-1 thrombin receptor antagonist in patients with acute coronary syndrome. Results from the LANCELOT ACS trial were...

September 15, 2010 – A study evaluating the level of platelet aggregation achieved after switching from clopidogrel (Plavix) 75 mg once-daily maintenance dosing plus aspirin to prasugrel (Effient...

September 15, 2010 – The U.S. Food and Drug Administration (FDA) has extended the time to complete its review of the new drug application (NDA) for ticagrelor (Brilinta), which is the first...

September 8, 2010 – The increased effectiveness of ticagrelor (Brilinta) in overcoming high platelet reactivity as compared to the gold-standard of clopidogrel (Plavix) was shown in data presented...

September 7, 2010 - With increasing rates of patients with atrial fibrillation program suffering from severe strokes, medical associations fear an epidemic. New developments in minimally invasive...

September 2, 2010 - Women and men with a 10-year cardiovascular disease risk of 5 percent or more and normal cholesterol levels but high levels of hsCRP, a protein associated with inflammation,...

August 30, 2010 – According to the results of a late-breaking analysis involving more than 200 000 patients in recent clinical trials, antihypertensive treatments with renin-angiotensin system (...

August 18, 2010 - The U.S. Food and Drug Administration (FDA) today proposed to withdraw approval of the drug midodrine hydrochloride, used to treat the low blood pressure condition orthostatic...

August 17, 2010 – Middle-aged and elderly Swedish women who regularly ate a small amount of chocolate had lower risks of heart failure in a study reported in Circulation: Heart Failure,...

August 2, 2010 – Research by an international team of scientists, including a University of California (UC), Davis, nutritionist, provides new evidence that cocoa and other foods rich in a class...

July 29, 2010 – A new, highly anticipated antiplatelet drug was recommended yesterday for final approval by the U.S. Food and Drug Administration (FDA) Cardiovascular and Renal Drugs Advisory...

July 26, 2010 – The U.S. Food and Drug Administration (FDA) approved the first generic version of Lovenox (enoxaparin sodium injection), an anticoagulant drug used for multiple indications,...

July 26, 2010 – A new three-in-one combination drug has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of hypertension in patients who do not respond to dual...

July 22, 2010 – Accumetrics Inc., Daiichi Sankyo Inc., and Eli Lilly and Co. recently announced that they have entered into a strategic collaboration in the United States to raise awareness about...

July 13, 2010 – AstraZeneca recently announced that the U.S. District Court has found that the substance patent protecting Crestor is valid and enforceable. In its ruling, the court found that no...

July 1, 2010 – Two medical companies say they will work with physicians to further investigate ways to manage genetic issues in antiplatelet therapy, after the U.S. Food and Drug Administration (...

July 1, 2010 – The U.S. Food and Drug Administration (FDA) recently added a warning to the information on clopidogrel (Plavix), as a result of new information indicating that variations in genetic...

July 1, 2010 – Clinical results have shown the Rheos System is successful in lowering blood pressure, CVRx Inc. announced this week at the European Society of Hypertension Meeting. The system is...

June 24, 2010 – The first cohort of patients was fully enrolled this week in a clinical study of a new drug meant to prevent restenosis in patients with peripheral arterial disease (PAD)....

June 21, 2010 – Long-term data presented today from Ardian’s Symplicity HTN-1 study demonstrate that the significant reductions in blood pressure achieved using renal denervation (RDN) treatment...

June 15, 2010 – Health care professionals can now get information on the diagnosis, pathology, and treatment of pulmonary arterial hypertension (PAH) on their smart phones. Actelion...

June 14, 2010 - High levels of high-density lipoprotein (HDL) — known as good cholesterol — can not only make a person two to three times less likely to develop heart disease, but also may lower...

June 8, 2010 – New study findings prove continuing warfarin therapy during pacemaker or defibrillator implantation in patients with moderate to high thromboembolic risk is safe and cost-effective...

June 2, 2010 – A portable point-of-care prothrombin time/international normalized ratio (PT/INR) analyzer was released this week. The system detect blood clotting time for patients stabilized on...

May 4, 2010 – A deal has been struck to produce a generic version of Merck & Company’s Zetia (ezetimibe). In the United States, the cholesterol modifying agent has annual U.S. sales of about $...

April 27, 2010 – A popular statin gained a new indication today in the European Union for prevention of major cardiovascular events in patients who are at high risk of having a first...

April 22, 2010 — An improved formulation of epoprostenol for the treatment of primary pulmonary arterial hypertension (PAH) and pulmonary hypertension is now commercially available.

April 19, 2010 – The U.S. Food and Drug Administration (FDA) recently cleared a generic version of metoprolol succinate extended-release tablets. The beta-blocker is used to treat angina, heart...

April 9, 2010 – A preclinical study shows the action of a toll-like receptor (TLR) antagonist helps reduce atherosclerosis in mice.

March 30, 2010 – The FDA granted tentative approval for Teva Pharmaceutical’s abbreviated new drug application (ANDA) to market a generic version of the anti-coagulant, Argatroban injection, 100mg...

March 23, 2010 – The U.S. Food and Drug Administration (FDA) recently added a boxed warning to the anti-blood clotting drug Plavix (clopidogrel), alerting patients and healthcare professionals...

March 23, 2010 – The FDA granted approval for diltiazem hydrochloride extended-release tablets to treat hypertension, which is the generic equivalent to Biovail Laboratories International SRL's...

March 19, 2010 – An experimental factor Xa inhibitor given to patients with non-valvular atrial fibrillation (AF) or atrial flutter and at least one risk factor for stroke, reduced the incidence...

March 18, 2010 — New data from two subanalyses of the Treating to New Targets (TNT) trial showed an increased dose of atorvastatin calcium (Lipitor), lowered cardiovascular events among high-risk...