News | June 02, 2015

Cincinnati Children’s Hospital Sees Potential of Synthetic MRI for Pediatrics

Technology creates multiple diagnostic sequences from a single acquisition, which could shorten exam time

SyMRI, Cincinnati, CCHMC, synthetic MRI, pediatrics

Image courtesy of SyntheticMR AB

June 2, 2015 — Cincinnati Children’s Hospital Medical Center (CCHMC) has evaluated synthetic magnetic resonance imaging (MRI) on pediatric cases to study and clinically validate its use on children. Results from the first part of the evaluation, which used SyMRI software, shows the synthetic images are diagnostically satisfactory in comparison with conventional sequences.

Long examination times are particularly challenging when examining children, who may even need to be given a general anesthetic during the exam. A faster workflow would therefore be especially valuable for pediatric applications. CCHMC sees an opportunity to improve the efficiency of pediatric MRI by being able to shorten the examination time with SyMRI. Synthetic imaging is being evaluated on pediatric cases at CCHMC in two steps. At first it has been ensured that the synthetic images are diagnostically sufficient in comparison with conventional sequences.

SyntheticMR AB develops and markets new MRI software solutions. It created the SyMRI Image software that provides fast MRI workflows, allowing high patient throughput, and SyMRI Neuro that enables automatic segmentation of brain tissue, providing objective decision support based on quantitative data. SyMRI is a CE-marked product. A customized version of SyMRI Image was introduced at the 2014 Radiological Society of North America (RSNA) annual meeting by SyntheticMR’s strategic partner GE Healthcare under the name MAGiC for GE’s line of Signa MRI systems.

“Because of the way the brain develops, a true strength of synthetic imaging that could be particularly useful in pediatric cases is the possibility of tuning image contrast afterwards and generating contrasts that usually are not acquired. Therefore the use of synthetic imaging, including interactive contrast changes during review, is now ongoing as the second step of evaluation. The ability to create multiple diagnostic sequences from a single acquisition may allow for substantial time savings and increased throughput”, said Blaise V. Jones, M.D., chief of neuroradiology, Cincinnati Children’s Hospital Medical Center.

While clinical validation of synthetic MRI relative to standard pulse sequences has been performed in adults, no such data has previously been available on children. The study at CCHMC evaluates synthetic MRI in children by comparing synthetic MR images with conventional MR images in children at both 1.5 and 3.0T in a blinded fashion to determine image quality and diagnostic efficacy relative to standard MRI.

“We see great potential for its use in clinical practice, and anticipate that synthetic imaging is going to help us discern subtle differences at grey matter to white matter interfaces, for example in epilepsy cases. Furthermore we expect that the quantitative T1, T2 and PD maps can assist us in monitoring the myelination process of white matter during the first years of brain development”, Jones continued.

SyMRI IMAGE from SyntheticMR optimizes the MRI workflow and shortens scan time using synthetic MRI. This is achieved by a single MR quantification scan of 5-7 minutes. Based on this single scan, conventional standard T1W, T2W and FLAIR images and any other combination of TE, TR and TI can be shown without rescanning the patient, allowing a substantial reduction in examination time.

For more information: www.symri.com

Related Content

HeartVista Announces One Click Autonomous MRI Solution
News | Magnetic Resonance Imaging (MRI) | November 25, 2018
HeartVista announced its artificial intelligence (AI)-driven, One-Click Autonomous MRI acquisition software for cardiac...
Carotid Artery MRI Improves Cardiovascular Disease Risk Assessment
News | Magnetic Resonance Imaging (MRI) | October 23, 2018
Magnetic resonance imaging (MRI) measurements of wall thickness in the carotid arteries improve cardiovascular disease...
FDA Clears Magnetom Sola 1.5T MRI From Siemens Healthineers
Technology | Magnetic Resonance Imaging (MRI) | October 09, 2018
The U.S. Food and Drug Administration (FDA) has cleared the Magnetom Sola, a 1.5 Tesla magnetic resonance imaging (MRI...
Stress Cardiac MRI Shows High Prognostic Value for Suspected Ischemia Patients
News | Magnetic Resonance Imaging (MRI) | September 17, 2018
Raymond Kwong, M.D., MPH, from the Harvard Medical School recently presented his findings on a study of how single-...
Rapid Cardiac MRI Technique May Cut Costs, Boost Care in Developing World
News | Magnetic Resonance Imaging (MRI) | August 29, 2018
A newly developed rapid imaging protocol quickly and cheaply diagnosed heart ailments in patients in Peru, according to...
Videos | Magnetic Resonance Imaging (MRI) | August 13, 2018
Haojie Wang, M.D., director of advanced cardiovascular MRI and a member of the heart valve clinic at Baylor Scott Whi
High Prevalence of Atherosclerosis Found in Lower Risk Patients
News | Magnetic Resonance Imaging (MRI) | June 08, 2018
Whole-body magnetic resonance angiography (MRA) found a surprisingly high prevalence of atherosclerosis in people...
A cardiac MRI scanner at the Houston Methodist DeBakey Heart and Vascular Center. There is growing concern that gadolinium contrast may cause chronic health problems in some patients.

A cardiac MRI scanner at the Houston Methodist DeBakey Heart and Vascular Center. There is growing concern that gadolinium contrast may cause chronic health problems in some patients.

Feature | Magnetic Resonance Imaging (MRI) | February 28, 2018 | Dave Fornell
One of the biggest concerns in radiology in recent years is the safety of gadolinium-based contrast agents (GBCAs) us
Contrast-Free Cardiac MRI May Better Assess Need for Mitral Valve Surgery
News | Magnetic Resonance Imaging (MRI) | February 27, 2018
A new study published in the Journal of the American College of Cardiology confirms non-invasive cardiac magnetic...
The FDA has cleared the Toshiba Vantage Galan 3.0T XGO Edition MRI from Canon Medical Systems.
Technology | Magnetic Resonance Imaging (MRI) | February 12, 2018
February 12, 2018 — Physicians now have access to more neuro and cardiac ...
Overlay Init