Feature | September 10, 2012

Baylor Researchers Begin Study of Link Between A-Fib and Cardiac Surgery

September 10, 2012 — Atrial fibrillation (AF) is a common complication of cardiac surgery, occurring in 10 to 40 percent of patients. Recent studies show it to be associated with poorer health following surgery and poorer long-term survival. Furthermore, development of AF after cardiac surgery leads to average additional healthcare costs of $15,000 to $20,000.

As part of an ongoing NIH National Heart Lung and Blood Institute study, Giovanni Filardo, Ph.D., MPH, and his team are executing a large national multicenter study assessing the effectiveness of optimal preventive and management strategies (based on American Heart Association/American College of Cardiology/European Society of Cardiology [AHA/ACC/ESC] and AACP guidelines) and their impact on the incidence of post-CABG (coronary artery bypass graft surgery) AF and long-term survival. Filardo is director of epidemiology at Baylor Health Care System’s Institute for Health Care Research and Improvement, and The Bradley Family Endowed Chair in cardiovascular epidemiology at Baylor University Medical Center.

"Currently we do not know what causes post-operative AF, nor how to identify patients at high risk and effectively prevent or mitigate this complication," said Filardo. "These are the questions that the study seeks to answer."

The retrospective study will look at patients who underwent isolated CABG surgery at Baylor University Medical Center (Dallas), Baylor Heart Hospital (Plano, Texas), Emory University (Atlanta), University of Virginia (Charlottesville, Va.) or Washington University (St. Louis). The study will provide insights into the prevention and management of post-operative AF, allowing healthcare providers to improve survival and decrease costs of care associated with CABG surgery.

More than 100,000 people in the United States and 1.5 million people worldwide undergo isolated CABG surgery each year. "Even taking the conservative estimate of 20 percent of those patients developing AF, the results of this study stand to improve survival for 300,000 people and save as much as $6 billion ($20,000 per person cost attributable to post-operative AF) in healthcare costs each year," said Filardo.

The purpose of the study is to identify the causes of new-onset AF in patients undergoing cardiac surgery, and whether current guidelines for high-risk patients are effective in preventing new-onset AF or if treatment protocols for those patients who do experience the condition are effective in improving survival. The study will be completed in April 2014.

For more information: www.baylorhealth.edu/research

Related Content

ICDs, non-ischemic cardiomyopathy, University of Alabama at Birmingham study, Circulation
News | Implantable Cardioverter Defibrillators (ICD)| January 18, 2017
A new study published in Circulation has found there is a 23 percent risk in reduction of all-cause mortality in non-...
LindaCare, expansion, remote patient monitoring, CIEDs, cardiac implantable electronic devices, United States
News | Remote Monitoring| January 18, 2017
LindaCare announced that it will open a new customer support facility in Connecticut to support growing interest in...
stress, brain activity, cardiovascular risk, PET-CT, MGH, ISSMS, The Lancet study
News | Cardiac Diagnostics| January 18, 2017
A study led by Massachusetts General Hospital (MGH) and Icahn School of Medicine at Mount Sinai (ISSMS) investigators...
ICDs, implantable cardioverter defibrillators, survival rate, elderly patients, JACC study
News | Implantable Cardioverter Defibrillators (ICD)| January 17, 2017
Of patients over age 65 who received an implantable cardioverter-defibrillator (ICD) after surviving sudden cardiac...
University of Utah, Frank Sachse, heart failure, LVAD implantation, left ventricular assist device, biomarker, t-system

Two patients may seem equally sick based upon clinical measures, but differences in their heart physiology could predict who has the potential to recover from heart failure. A study carried out by scientists at the University of Utah finds that patients whose hearts have flattened t-tubules have a decreased chance of showing signs of recovery after implanting a mechanical heart pump. Ordinarily, t-tubules in the heart are long, thin, and rounded. Image courtesy of Frank Sachse.

News | Cardiac Diagnostics| January 17, 2017
Investigators at the University of Utah have identified distinct differences in the hearts of advanced heart failure...
Synergy stent, abluminal polymer DES, bioresorbable polymer DES, bioresorbable polymer metallic stent

The Synergy stent is the first FDA cleared drug-eluting stent to use a bioresorbable polymer drug carrier. When the polymer dissolves after about four months, the devices become a bare metal stent. The technology is supposed to reduce the rate of late stent thrombosis due to vessel inflammation caused by durable polymers.

Feature | Stents Bioresorbable| January 17, 2017 | Dave Fornell
One of the big advancements in drug-eluting stent (DES) technology has been the development of bioresorbable polymers
St. Jude Medical, Amplatzer Amulet LAA Occluder, observational study, TCT 2016
News | Left Atrial Appendage (LAA) Occluders| November 03, 2016
St. Jude Medical Inc. presented favorable results from the largest observational study to date of the company’s...
Medtronic, CoreValve Evolut R TAVR system, U.S. IDE Study, TCT 2016
News | Heart Valve Technology| November 03, 2016
Medtronic plc unveiled new clinical data showing that patients treated with the self-expanding CoreValve Evolut R...
open-heart surgery, PCI, percutaneous coronary intervention, NOBLE trial, left main coronary artery disease, LMCAD, TCT 2016
News | Cardiovascular Surgery| November 03, 2016
Coronary artery bypass (CABG) surgery is the standard treatment for revascularization in patients with left main...
News | Drug-Eluting Balloons| November 03, 2016
The Spectranetics Corp. announced that it has submitted to the U.S. Food & Drug Administration (FDA) its Pre-Market...
Overlay Init