Feature | July 13, 2012

The Offbeat: Baby Not Harmed by Therapeutic Hypothermia During Pregnant Woman's Cardiac Arrest

July 13, 2012 ? An otherwise healthy pregnant woman who suffered cardiac arrest and was resuscitated, therapeutically cooled and then re-warmed, delivered a healthy, full-term baby 19 weeks later. Researchers published a unique case report online last week in Annals of Emergency Medicine.

"We have over years years of clinical follow-up of the mother and child and both are doing well, with the child exhibiting normal developmental growth at long-term follow-up," said lead author Aakash Chauhan, M.D., MBA, of Allegheny General Hospital in Pittsburgh, Penn. "The mother and child both had great outcomes despite an incredibly harrowing episode during her pregnancy."

The patient, a 33-year-old woman in her 20th week of pregnancy, suffered cardiac arrest while at a church gathering. She was given CPR, defibrillated and transported to the emergency department. Three hours after arriving at the hospital, the patient's body was cooled to approximately 90 degrees Fahrenheit.  She was kept at a hypothermic temperature for 12 hours and then rewarmed to a normal temperature.  While the patient was being cooled, doctors monitored the fetus and detected fetal shivering, which stopped once the mother was re-warmed. 

The patient stayed in the hospital for 10 more days and was implanted with a cardioverter-defibrillator (ICD).  She resumed her work and normal activities of daily living for the remainder of her pregnancy and delivered a healthy baby boy at 39 weeks. 

Doctors evaluated the boy at 1, 2, 3, 6, 12 and 36 months of age and found he has reached all the normal development milestones.

"We would not normally treat a rare cardiac arrest pregnant patient with hypothermia because hypothermia was untested in this population and therefore considered too risky for the fetus," said Naseer Nasser M.D., the cardiologist who directed her care at Memorial Hospital in South Bend, Indiana. "However, without the recently proven benefit of hypothermia for cardiac arrest, mother and child would not have benefited from this lifesaving advance. This report suggests that with prudent clinical judgment, vigilance and a dedicated multi-disciplinary team, therapeutic hypothermia can be offered to pregnant women who survive cardiac arrest."

Michael Donnino, M.D., of Beth Israel Deaconess Medical Center in Boston, Mass, a co-author of the paper who is a member of the advanced cardiac life support subcommittee at the American Heart Association (AHA), said, "Publishing this case will add to the paucity of literature on the safety of hypothermia in pregnancy and provide support for the AHA's current recommendation of 'may consider use' of hypothermia in pregnancy."

Annals of Emergency Medicine is the peer-reviewed scientific journal for the American College of Emergency Physicians, the national medical society representing emergency medicine.

For more information: www.acep.org

 

 

Related Content

St. Jude Medical, Amplatzer Amulet LAA Occluder, observational study, TCT 2016
News | Left Atrial Appendage (LAA) Occluders| November 03, 2016
St. Jude Medical Inc. presented favorable results from the largest observational study to date of the company’s...
Medtronic, CoreValve Evolut R TAVR system, U.S. IDE Study, TCT 2016
News | Heart Valve Technology| November 03, 2016
Medtronic plc unveiled new clinical data showing that patients treated with the self-expanding CoreValve Evolut R...
open-heart surgery, PCI, percutaneous coronary intervention, NOBLE trial, left main coronary artery disease, LMCAD, TCT 2016
News | Cardiovascular Surgery| November 03, 2016
Coronary artery bypass (CABG) surgery is the standard treatment for revascularization in patients with left main...
News | Drug-Eluting Balloons| November 03, 2016
The Spectranetics Corp. announced that it has submitted to the U.S. Food & Drug Administration (FDA) its Pre-Market...
Medtronic, Resolute Integrity DES, drug-eluting stent, BIO-RESORT study, TCT 2016
News | Stents Drug Eluting| November 02, 2016
Investigators recently unveiled clinical data from the independent BIO-RESORT study, representing the first all-comers...
Medtronic, Harmony TPV, transcatheter pulmonary valve, clinical study results, TCT 2016
News | Heart Valve Technology| November 02, 2016
Medtronic plc recently announced new clinical data for the Harmony Transcatheter Pulmonary Valve (TPV) from its early...
Medtronic, Drug-Filled Stent, DFS, RevElution trial, first clinical data, TCT 2016, Stephen Worthley
News | Stents Drug Eluting| November 01, 2016
November 1, 2016 — Medtronic plc unveiled the first clinical outcomes of its novel...
Edwards, Sapien transcatheter heart valve, PARTNER trial, five-year echo data, TCT 2016
News | Heart Valve Technology| November 01, 2016
Edwards Lifesciences Corp. announced new five-year hemodynamic data from the PARTNER Trial demonstrating excellent...
Medtronic, CoreValve Evolut R TAVR system, TCT 2016, FORWARD Study, STS/ACC TVT Registry
News | Heart Valve Technology| October 31, 2016
Medtronic plc presented new positive data from two large registries aimed at evaluating 30-day clinical performance...
white coat hypertension, heart disease risk, blood pressure spike, doctor's office, Journal of the American College of Cardiology, JACC study
News | Hypertension| October 31, 2016
White coat hypertension, where patients have high blood pressure readings in a medical setting but normal blood...
Overlay Init