Feature | Heart Valve Technology | October 29, 2019

NFL Great Ed White Gets New TAVR Heart Valve at Scripps

New FDA-cleared minimally invasive TAVR offers alternative to open-heart surgery

 Retired National Football League (NFL) star Ed White, the former Chargers guard and four-time Pro Bowler, waited until the FDA approved TAVR for low-risk patients like himself to avoid open-heart surgery.

Retired National Football League (NFL) star Ed White, the former Chargers guard and four-time Pro Bowler, waited until the FDA approved TAVR for low-risk patients like himself to avoid open-heart surgery.


October 29, 2019 — When Scripps cardiologists discovered early in 2019 that retired National Football League (NFL) great Ed White needed to replace his faulty aortic heart valve, the former Chargers guard and four-time Pro Bowler knew he did not want to take on the risk of open-heart surgery. But, at the time, that was his only option.

Instead, the 72-year-old Julian, Calif., resident put off the replacement in hopes that an innovative minimally invasive procedure, known as transcatheter aortic valve replacement (TAVR), would soon gain U.S. Food and Drug Administration (FDA) approved for patients like him who were considered healthy enough to undergo open-heart surgery. His game plan paid off. In August, when the FDA cleared the use of two TAVR devices for use in low-risk surgical risk patients, essentially opening up the use of TAVR as a second option for all patients instead of open heart surgery

In September, cardiologists at Scripps Memorial Hospital La Jolla threaded a collapsible heart valve through a small incision in White’s leg and into the femoral artery leading to his heart. Once in position in the heart, they expanded the TAVR device into place where it took over the original valve’s function of enabling oxygen-rich blood to flow efficiently out of the heart.

It is the same procedure that rock music legend Mick Jagger underwent earlier this year after his health problems forced the Rolling Stones to postpone their North American concert tour. 

The Sapien 3 TAVR valve implanted in NFL star Ed White.

The Sapien 3 TAVR valve implanted in NFL star Ed White.

TAVR Newly Approved by the FDA

White is one of the first people in San Diego County to undergo TAVR after the FDA approved the procedure for patients Aug. 16 for patients with low surgical mortality risk. TAVR was previously available only for patients too ill or frail to undergo open-heart surgery.

“This procedure has revolutionized heart valve surgery by giving patients like Ed a much less complicated option for treatment that doesn’t involve the prolonged recovery of  open-chest surgery,” said Paul Teirstein, M.D., Scripps Clinic chief of cardiology, the interventional cardiologist who performed the TAVR procedure on White. “Here at Scripps, we have been doing the TAVR procedure on high-risk surgery patients since 2011, and we’ve seen over and over how this technique, requiring only one night in the hospital, extends and improves patients’ lives. Now we can offer this procedure to almost all patients with aortic stenosis.”

Scripps was the only health system in San Diego County that participated in clinical trials validating TAVR in low-risk patients. Results from those studies, which were reported in March, showed that TAVR patients had significantly fewer strokes, a lower chance of death and significantly faster recoveries when compared with patients whose aortic valves were replaced during open-heart surgery.

While open-heart surgery patients often spend a week or more in the hospital and up to six weeks recovering, most TAVR recipients leave the hospital the morning after the procedure and return to usual activities in a few days.

In 2017, when the old standards were still in place for low-risk cases, about 25,600 people in the United States underwent open-heart surgery for an aortic valve replacement, according to the Society of Thoracic Surgeons (STS).

Going forward, Teirstein predicts most of the 70,000 aortic valve replacements done annually in the United States will use the TAVR procedure.

TAVR Patient Ed White speaks with Paul Teirstein, M.D., Scripps Clinic chief of cardiology, the interventional cardiologist who performed the TAVR procedure on White, following the procedure Sept. 3.

TAVR Patient Ed White speaks with Paul Teirstein, M.D., Scripps Clinic chief of cardiology, the interventional cardiologist who performed the procedure on White Sept. 3.

 

TAVR Clinical Trial Not an Option for White

White’s heart valve troubles began in March 2019, He started experiencing shortness of breath and overall discomfort during a cruise off the west coast of Mexico with his wife to celebrate her birthday. After a short stay in a hospital in Mexico, White returned to San Diego where he consulted with Teirstein, Scripps Clinic cardiothoracic surgeon Sam Baradarian, M.D., and Scripps cardiologist Kevin Rapeport, M.D.

He was diagnosed with aortic stenosis, a narrowing of the aortic heart valve which reduces or blocks the flow of blood from the heart to the rest of the body. It is one of the most common and most serious valve disease problems that can lead to heart failure, which can be fatal.

Initially, White and his doctors thought he would qualify for the TAVR clinical trial at Scripps. But after undergoing testing for the study, his valve size turned out to be too large to qualify him for the trial.

Facing open-heart surgery, White opted to postpone treatment despite a risk of suffering cardiac arrest before the TAVR procedure became more widely available.

“At my age, quality of life is really important,” White said. “I didn’t want to take on the added risks that come with surgery tied to full sedation and a much longer recovery timeline. I talked with family members, friends and the other medical experts I know, and the consensus was to wait for TAVR.”

While waiting for his new heart valve, White focused on improving his overall health with a daily exercise routine that included three-mile hikes in the local mountains and 30-minute swims in a pool. “I looked at it as though I was going to football training camp again,” he said.

White received his new valve Sept. 3 during an hour-and-a-half-long procedure in the catheterization laboratory in the Scripps Clinic John R. Anderson V Medical Pavilion, which is on the Scripps La Jolla campus. He was discharged the next day.

Paul Teirstein, M.D., Scripps Clinic chief of cardiology, performing the TAVR procedure on White.

Paul Teirstein, M.D., Scripps Clinic chief of cardiology, performing the TAVR procedure on White.

Ed White's Football Career

Since retiring from the NFL as an offensive lineman with the San Diego Chargers in 1985, White has mostly lived in the San Diego area. He previously played for the Minnesota Vikings and appeared in four Super Bowls with that team between 1969 and 1976. He was selected to play in the Pro Bowl in 1975, 1976, 1977 and 1979. In college, he was an All-American lineman for the University of California, Berkeley Golden Bears.

After his playing career, White built a reputation as one of the best offensive line coaches in the game during coaching stints with the Chargers, Los Angeles Rams, San Diego State University Aztecs and Cal Bears.

 
Related TAVR Content:

VIDEO: The Expansion of TAVR Following the FDA Clearing its Use in All Patients

FDA Approves TAVR for Low-risk Patients Creates A Paradigm Shift in Cardiology

Similar Outcomes for TAVR vs. SAVR in Intermediate Surgical Risk Patients

VIDEO: How to Get Referral Patients Into a Structural Heart Program

National Coverage Determination Will Make TAVR Available to More Patients at More Centers

VIDEO: TAVR Stands Equal to Surgical Valve Replacement — Interview with Michael Reardon, M.D.

Study Finds TAVR Can Be Considered for Patients in All Surgical Risk Classes

VIDEO: Edwards Lifesciences Sapien 3 TAVR Procedural Animation

TAVR Performs Well Compared to Surgical Aortic Valve Replacement in Low Risk Patients

CMS Finalizes Updates to Coverage Policy for Transcatheter Aortic Valve Replacement

TAVR Outperforms Surgery in Younger, Low-Risk Aortic Stenosis Patients

VIDEO: Tracking Transcatheter Valve Outcomes in the STS-ACC TVT Registry — interview with John Carroll, M.D.

Interventional Imagers: The Conductors of the Heart Team Orchestra

VIDEO: TAVR For Asymptomatic Severe Aortic Stenosis — Interview with  Philippe Genereux, M.D.

How to Perform Transcaval TAVR Access

TAVR Operator and Hospital Requirements Outlined in 2018 AATS/ACC/SCAI/STS Expert Consensus

VIDEO: TAVR for Degenerated Surgical Valves, Valve-in-Valve TAVR Procedures — Interview with Sammy Elmariah, M.D.

VIDEO: Advice For Hospitals Starting a Structural Heart Program — interview with John Carroll, M.D.


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