News | June 25, 2013

Study Finds Circulation More Likely to Return With Zoll AutoPulse

June 25, 2013 — Zoll Medical Corp., a manufacturer of medical devices and related software solutions, announced that a paper published in Critical Care Medicine reported the likelihood of achieving a return of spontaneous circulation (ROSC) after sudden cardiac arrest (SCA) is 62 percent greater when the AutoPulse noninvasive cardiac support pump is used to deliver CPR chest compressions.

The paper is a meta-analysis of changes to ROSC rates from 12 previously published human studies that compared the use of manual and mechanically delivered chest compressions during out-of-hospital cardiac arrests (OHCA). Collectively these studies included 6,538 patients. The analysis showed use of the AutoPulse, which delivers circumferential compressions with a load-distributing band, was 62 percent more likely to produce ROSC. In contrast the analysis demonstrated that a piston-driven, sternal compression technology had no incremental impact on ROSC rates.

Commenting on the paper, lead author Mark Westfall, DO, FACEP, FACP, Theda Clark Regional Medical Center, Neenah, Wis., said, “This analysis contributes greatly to our understanding of the impact mechanical CPR systems have in the pre-hospital setting. The use of ROSC as a primary endpoint is most appropriate in this environment. Whereas survival is an endpoint influenced by a variety of factors that aren’t necessarily related to the quality of CPR performed in the field, the ability to achieve ROSC in the pre-hospital setting is closely linked to the delivery of high-quality chest compressions.”

“This is the first paper that looks at the efficacy of multiple mechanical CPR technologies,” said Jonathan A. Rennert, president of ZOLL. “The analysis produced two major findings. First, it showed a 62 percent greater likelihood of achieving ROSC with the AutoPulse, while a parallel analysis showed no change in ROSC when a piston-driven device was used to provide chest compressions. Secondly, the analysis confirms expert opinion that findings from one mechanical CPR technology cannot be applied to another.”

The AutoPulse is the only mechanical CPR system to have shown improved survival in comparative clinical trials. The AutoPulse more than tripled survival compared to typical CPR during witnessed shockable arrests. It uses the load-distributing LifeBand to deliver unprecedented circulation by squeezing the entire chest to improve blood flow to a patient’s heart and brain during sudden cardiac arrest. The AutoPulse delivers high-quality, uninterrupted CPR chest compressions to maintain myocardial and cerebral perfusion.

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