FFR Technologies

This channel includes news and new technology innovations for fractional flow reserve (FFR) wires, catheters and systems used to measure blood flow across a coronary lesion to determine if a stent is needed or if the plaque stenosis can be treated medically. The section includes iFR, instantaneous wave-free ratio, systems used in the cath lab and noninvasive FFR technologies including computed tomography-FFR. This is also referred to as CT-FFR or FFR-CT.

The CathWorks angiography image derived FFR assessment system has received national reimbursement approval in Japan. The system uses a rotational angiography image dataset taken while the patient is in the cath lab to quickly reconstruct a 3-D coronary tree showing FFR numbers for all of the artery segments. 

The CathWorks angiography image derived FFR assessment system has received national reimbursement approval in Japan. The system uses a rotational angiography image dataset taken while the patient is in the cath lab to quickly reconstruct a 3-D coronary tree showing FFR numbers for all of the artery segments. 

News | FFR Technologies | July 26, 2021
CathWorks FFRangio System Receives National Reimbursement Approval in Japan
July 26, 2021 – CathWorks announced that the Japanese Ministry of Health, Labour and Welfare (MHLW) has approved the...
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An example of the Medis QCA angiography imaging derived fractional flow reserve (FFR) assessment. This technology removes the need for pressure wires and adenosine used in traditional FFR assessments of the coronary arteries.

An example of the Medis QCA angiography imaging derived fractional flow reserve (FFR) assessment. This technology removes the need for pressure wires and adenosine used in traditional FFR assessments of the coronary arteries.

News | Cath Lab | July 22, 2021
Quantitative Flow Ratio (QFR) Study Looks at Impact on Appropriateness of Revascularization in the PIONEER-IV Trial
July 22, 2021 — Medis Medical Imaging is partnering with CORRIB Core Lab and Sinomed in randomized clinical trial of...
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An example of HeartFlow's FFR-CT analysis of blockage severity in a patient's coronary vessels based on a cardiac CT scan.

An example of HeartFlow's FFR-CT analysis of blockage severity in a patient's coronary vessels based on a cardiac CT scan.

News | FFR Technologies | July 15, 2021
HeartFlow Becomes Publicly Traded Company in Merger With Longview Acquisition Corp.
July 15, 2021 — HeartFlow, which has commercialized noninvasive computed tomography derived fractional flow reserve (...
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The Philips Healthcare SyncVision system co-registers iFR hemodynamic blood flow measurements to live angiograms to enable easier assessment of which lesions in a vessel need to be stented and which can be left alone and treated medically.

The Philips Healthcare SyncVision system co-registers iFR hemodynamic  blood flow measurements to live angiograms to enable easier assessment of which lesions in a vessel need to be stented and which can be left alone and treated medically.

News | FFR Technologies | June 22, 2021
First Patient Enrolled in DEFINE GPS Study to Assess PCI Guided by Co-registered iFR Versus Angiography
June 22, 2021 – Philips Healthcare announced the official start of the DEFINE GPS study, with the first patient being...
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Some of the top technology news from ACC 2021. Top left, the LAAOS III trial showed benefit when surgeons seal off the LAA during other open heart procedures. Bottom left, the ReCor Paradise renal denervation system helped lower blood pressure in patients who did not respond to medication. Top right, for patients with both heart failure and AFib it makes no differences is therapy is focused on controlling the heart rhythm or heart rate. Bottom right, the FLOWER-MI trial found no benefit to FFR-guided PCI.

Some of the top technology news from ACC 2021. Top left, the LAAOS III trial showed benefit when surgeons seal off the LAA during other open heart procedures. Bottom left, the ReCor Paradise renal denervation system helped lower blood pressure in patients who did not respond to medication. Top right, for patients with both heart failure and AFib it makes no difference if therapy is focused on controlling the heart rhythm or heart rate. Bottom right, the FLOWER-MI trial found no benefit to FFR-guided PCI in STEMI with multi-vessel disease.

Feature | ACC | June 08, 2021 | By Dave Fornell, Editor
Key Cardiology Technology Takeaways at ACC 2021
Here are the top 10 takeaways from the late-breaking studies on cardiovascular technologies presented at the 2021...
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The FLOWER-MI trial presented at ACC 2021 found no benefit to FFR-guided PCI in STEMI with multi-vessel disease. #ACC21 #ACC2021 #FFR

The FLOWER-MI trial presented at ACC 2021 found no benefit to FFR-guided PCI in STEMI with multi-vessel disease.

News | FFR Technologies | May 17, 2021
No Benefit to FFR-guided PCI in STEMI Patients With Multi-Vessel Disease
May 17, 2021 — In patients who received a coronary stent for an ST-elevation myocardial infarction (STEMI) heart attack...
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The digital technology is reducing reliance on unnecessary invasive diagnostic procedures and is cutting hospital waiting times
News | Artificial Intelligence | May 12, 2021
NICE Renews Support for Use of AI-powered HeartFlow Analysis
May 12, 2021 — HeartFlow, Inc., a leader in revolutionizing precision heartcare, today announced that the National...
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Videos | FFR Technologies | December 16, 2020
VIDEO: Example of the Medis QFR Angiography Image Derived FFR System
This is an example of the Medis Medical Imaging Quantitative Flow Ratio (QFR) system that offers a fractional flow...
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The Medis Quantitative Flow Ratio (QFR) is a novel, non-invasive, angiography-based physiologic FFR-like assessment of the presence and extent of coronary artery disease.

The Medis Quantitative Flow Ratio (QFR) is a novel, non-invasive, angiography-based physiologic FFR-like assessment of the presence and extent of coronary artery disease. 

News | FFR Technologies | December 16, 2020
Acist Medical Partners With Medis to Distribute Angiography Image Derived FFR Quantification System
December 16, 2020 – Acist Medical Systems Inc. announced a formal distribution partnership with Medis Medical Imaging...
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Angiography with a co-registered view of pressure drops according iFR readings in a coronary vessel. The DEFINE PCI study showed patients had improved outcomes and less recurrent chest pain at one year using iFR physiologic measurements combined with landmarks shown on angiographic imaging to better guide therapy. Image by Philips Healthcare. #TCT #TCT2020 #TCTconnect

Angiography with a co-registered view of pressure drops according iFR readings in a coronary vessel. The DEFINE PCI study showed patients had improved outcomes and less recurrent chest pain at one year using iFR physiologic measurements combined with landmarks shown on angiographic imaging to better guide therapy. Image by Philips Healthcare

Feature | FFR Technologies | October 30, 2020 | Dave Fornell, Editor
FFR Studies Find Several Surprises at TCT 2020
Fractional flow reserve (FFR) is considered the gold standard measure whether a coronary lesions needs a percutaneous...
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Example of FFR assessment of the coronary hemodynamic flow in lesions using the Philips FFR, iFR assessment system. #FFR #TCTconnect #TCT2020

FFR assessment of a coronary lesion using the Philips Healthcare Volcano FFR system.

News | FFR Technologies | October 23, 2020
Deferring PCI in FFR-Abnormal Lesions With Preserved Coronary Flow Reserve Not Associated With Similar Outcomes as Untreated Lesions with Normal FFR
October 23, 2020 – A new observational study of deferred lesions following combined fractional flow reserve (FFR) and...
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Fractional Flow reserve (FFR) selection on the Abbott, St. Jude FFR system console. The TARGET FFR study at #TCT2020 #TCTconnect.
News | FFR Technologies | October 23, 2020
FFR-guided PCI Optimization Strategy May Lead to Improved Outcomes
October 23, 2020 – Results from the randomized controlled TARGET FFR trial show that while a physiology-guided...
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An example of a HeartFlow FFR-CT image showing the blood flow through what looked like a significant blockage on CT angiography alone actually was not flow limiting based on computational fluid dynamics. Use of the technology was supposed to reduce the number of diagnostic catheterizations in the FORECAST trial, but the costs of FFR-CT were not offset enough to show cost savings. #TCT2020 #TCTconnect

An example of a HeartFlow FFR-CT image showing the blood flow through what looked like a significant blockage on CT angiography alone, actually was not flow-limiting based on computational fluid dynamics. Use of the technology was supposed to reduce the number of diagnostic catheterizations in the FORECAST trial, but the costs of FFR-CT were not offset enough to show cost savings.

News | FFR Technologies | October 22, 2020 | Dave Fornell, Editor
FFR-CT Did Not Significantly Reduce Costs But Reduced Rates of Invasive Coronary Angiography
October 22, 2020 – In the FORECAST randomized clinical trial, the use of fractional flow reserve (FFR) derived from...
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A longitudinal vessel assessment may demonstrate co-existence of multiple plaque morphologies on OCT, including superficial calcification with thrombus, healed plaque, plaque rupture, lipidic plaque with a thin capped fibrous atheroma (TCFA). #TCTconnect #TCT2020

A longitudinal vessel assessment may demonstrate co-existence of multiple plaque morphologies on OCT, including superficial calcification with thrombus, healed plaque, plaque rupture, lipidic plaque with a thin cap fibro-atheroma (TCFA).

News | Cath Lab | October 18, 2020
Combined FFR and OCT Imaging Can Improve Accuracy of High-Risk Lesion Identification in Patients With Diabetes
October 18, 2020 – Data from the COMBINE (OCT-FFR) study found that the use of FFR combined with OCT imaging can help...
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Philip's co-registration technology showing angiography overlaid with iFR in a coronary vessel segment with a system of dots that show regions where the hemodynamic pressure drops occur. This can aid in identifying culprit lesions. #TCT #TCT2020 #TCTconnect

Philip's co-registration technology showing angiography overlaid with iFR in a coronary vessel segment with a system of dots that show regions where the hemodynamic pressure drops occur. This can aid in identifying culprit lesions.

News | FFR Technologies | October 15, 2020
DEFINE PCI Study One-year Data Show Potential of Treating Residual Ischemia to Improve Outcomes for Coronary Stenting
October 15, 2020 — The one-year results of the late-breaking DEFINE PCI study showed patients had improved outcomes and...
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