Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

COVID-19 disrupted all aspects of science and medicine and unmasked striking disparities and opportunities for transformation. Coronavirus impact this past year is expected to result in a massive rise in new cases of chronic health conditions, including cardiolvascular disease and heart failure.
News | Coronavirus (COVID-19) | April 07, 2021
April 6, 2021 — A tsunami of chronic health conditions as a result of the COVID-19 (SARS-CoV-2) pandemic, especially...
The Acutus Medical AcQBlate Force sensing ablation catheter.

The Acutus Medical AcQBlate Force sensing ablation catheter.

News | Ablation Systems | April 05, 2021
April 5, 2021 — Acutus Medical today announced initial U.S. enrollments in the company’s AcQForce Flutter...
Videos | Coronavirus (COVID-19) | April 01, 2021
Behnood Bikdeli M.D., a cardiologist at the Brigham and Women’s Hospital, Harvard Medical School, Boston, offers an...
Researchers found a relationship between stress-associated neurobiological activity on 18F-FDG PET-CT imaging and risk for subsequent Takotsubo syndrome impacting the heart.

Researchers found a relationship between stress-associated neurobiological activity on 18F-FDG PET-CT imaging and risk for subsequent Takotsubo syndrome impacting the heart.

News | March 31, 2021
March 31, 2021 — Heightened activity in the brain, caused by stressful events, is linked to the risk of developing a...
Videos | Structural Heart | March 23, 2021
Interview with Scott E. Kasner, M.D., who served as the principle investigator for the Gore Cardioform REDUCE trial,...
Top left, electromechanical wave imaging (EWI) isochrone renderings showing the activation points of the myocardium based on echocardiography axial strain measurements. Bottom right, EWI images overlaid on patient's CT scan of the heart.

Top left, electromechanical wave imaging (EWI) isochrone renderings showing the activation points of the myocardium based on echocardiography axial strain measurements. Bottom right, EWI images overlaid on patient's CT scan of the heart.

News | EP Lab | March 23, 2021
March 23, 2021 — Researchers at Columbia University are using cardiac ultrasound to improve the critical need to...
MRI scan of a damaged heart. Blue means reduced blood flow, orange is good blood flow. In this figure the inferior part of the heart shows dark blue, so the myocardial blood flow is very reduced. The angiogram shows the coronary artery which supplies the blood to this part of the heart is occluded. The three colored MRI images show different slices of the heart — the basal mid and apical slices. Image courtesy of European Heart Journal #COVID #COVID19

MRI scan of a damaged heart. Blue means reduced blood flow, orange is good blood flow. In this figure the inferior part of the heart shows dark blue, so the myocardial blood flow is very reduced. The angiogram shows the coronary artery which supplies the blood to this part of the heart is occluded. The three colored MRI images show different slices of the heart — the basal mid and apical slices. Image courtesy of European Heart Journal

News | Coronavirus (COVID-19) | March 17, 2021
March 17, 2021 — Around 50% of patients who have been hospitalized with severe COVID-19 (SARS-CoV-2) and have damage to...
A study from Washington University School of Medicine in St. Louis provides evidence that the coronavirus can invade and replicate inside heart muscle cells, causing cell death and interfering with heart muscle contraction. The image of engineered heart tissue shows human heart muscle cells (red) infected with COVID-19 (SARS-CoV-2) (green). Image by Lina Greenberg.

A study from Washington University School of Medicine in St. Louis provides evidence that the coronavirus can invade and replicate inside heart muscle cells, causing cell death and interfering with heart muscle contraction. The image of engineered heart tissue shows human heart muscle cells (red) infected with COVID-19 (SARS-CoV-2) (green). Image by Lina Greenberg.

Feature | Coronavirus (COVID-19) | March 12, 2021
March 12, 2021 — Since early in the pandemic, COVID-19 has been associated with heart problems, including reduced...
The Philips Stellarex low-dose paclitaxel drug-coated balloon prior to insertion in the cath lab. Five-year ILLUMENATE EU RCT and Pivotal Data Confirm Safety of Philips Stellarex Low-dose Drug-coated Balloon

The Philips Stellarex low-dose paclitaxel drug-coated balloon prior to insertion in the cath lab.

News | Drug-Eluting Balloons | March 12, 2021
March 12, 2021 — Philips Healthcare announced the final, five-year results of two major randomized controlled trials (...
Interactions between capillary function, inflammation, hypoxia, and neurotransmission. The expression of ACE2 and other SARS‐CoV‐2 entry factors on parenchymal cells and observations of infected cells in biopsy material hold important clues to understand COVID‐19‐related organ damage. COVID-19 Blood Vessel Damage May Cause Brain Fog and Other Long-hauler Symptoms

Interactions between capillary function, inflammation, hypoxia, and neurotransmission. The expression of ACE2 and other SARS‐CoV‐2 entry factors on parenchymal cells and observations of infected cells in biopsy material hold important clues to understand COVID‐19‐related organ damage. Find more figures and read the full study.

News | Coronavirus (COVID-19) | March 12, 2021
March 12, 2021 — A new review suggests that blood vessel damage and impaired oxygen delivery related to COVID-19 play a...
AMERICAN COLLEGE OF CARDIOLOGY (ACC) Late-breaking clinical trial study presentations at ACC.21. @ACC21 @ACC2021
Feature | ACC | March 08, 2021 | Dave Fornell, Editor
The latest cardiology practice-changing scientific breakthrough, late-breaking study presentations have been announced...
News | Cardiac Resynchronization Therapy Devices (CRT) | March 03, 2021
March 3, 2021 — Medtronic announced new results from the landmark REVERSE trial, evaluating outcomes of cardiac...
Astronaut Jessica Meir “feeds” a set of the University of Washington’s engineered heart tissues (inside the green-topped case at center) riding aboard the International Space Station as part of a test of micro-gravity on heart health. Image courtesy of NASA. 

Astronaut Jessica Meir “feeds” a set of the University of Washington’s engineered heart tissues (inside the green-topped case at center) riding aboard the International Space Station as part of a test of micro-gravity on heart health. Image courtesy of NASA. 

Feature | Stem Cell Therapies | February 25, 2021 | By Andy Freeberg
The University of Washington (UW) in Seattle has developed engineered heart tissue that beats. Though minuscule, the...
An example of cardiac ultrasound longitudinal strain measurements on the Epsilon EchoInsight software. This can be used to assess cardiotoxicity from chemotherapy agents.  Cardio-oncology

An example of cardiac ultrasound longitudinal strain measurements on the Epsilon EchoInsight software. This can be used to assess cardiotoxicity from chemotherapy agents. 

News | Cardio-oncology | February 25, 2021
February 25, 2020 — Results of a multi-centre, international, clinical trial co-led by Peter Munk Cardiac Centre (PMCC...
UK hospU.K. hospital admissions for heart attacks and heart failure were reduced by more than 50 percent in the spring of 2020 and by more than a third in the second wave of COVID-19 as people fear going to hospitals and ignore serious symptoms.ital admissions for heart attacks and heart failure have been reduced by COVID-19 as people fear going to hospitals. Getty Images #COVIDUK #COVID19

U.K. hospital admissions for heart attacks and heart failure were reduced by more than 50 percent in the spring of 2020 and by more than a third in the second wave of COVID-19 as people fear going to hospitals and ignore serious symptoms. Getty Images

News | Coronavirus (COVID-19) | February 24, 2021
February 24, 2021 — A study of admissions for acute myocardial infarction (AMI) and heart failure (HF) in the U.K....