Aug. 15, 2024 — According to a new study being presented at ACC Asia 2024 in Delhi, India, drinking over 400 mg of caffeine per day on most days of the week could increase the susceptibility of healthy individuals to cardiovascular disease.
“Regular caffeine consumption could disturb the parasympathetic system, leading to elevated blood pressure and heart rates,” said lead author Nency Kagathara, MBBS, Department of Internal Medicine, Zydus Medical College and Hospital, Dahod, India. “Our study sought to determine the effects of chronic caffeine consumption on heart health, specifically the recovery of heart rate and blood pressure.”
Chronic caffeine consumption was defined as the intake of any caffeinated drinks five days per week for more than one year. The study focused on tea, coffee and aerated beverages such as soda and energy drinks. The authors evaluated a randomized group of 92 normotensive and healthy individuals between the ages of 18 and 45 years. All participants had their blood pressure and pulse measured and underwent a three-minute step test. Blood pressure and heart rates were measured at one minute and five minutes after the test. The authors recorded information on each participant’s sociodemographic data and daily caffeine intake.
The results found that 19.6 percent of the participants consumed more than 400 mg of caffeine every day, which translates to about four cups of coffee, 10 cans of soda or two energy drinks. Chronic caffeine consumption at 400 mg daily was shown to significantly impact the autonomic nervous system, raising the heart rate and blood pressure over time.
Researchers said the highest daily caffeine intakes were observed in participants who were female, employed in business and management roles, and living in urban areas.
Those who consumed the highest amounts, chronic caffeine consumption of more than 600 mg of caffeine per day, had significantly elevated heart rates and blood pressure after five minutes of rest following the step test
“Due to its effect on the autonomic nervous system, regular caffeine consumption could put otherwise healthy individuals at risk of hypertension and other cardiovascular events,” said Kagathara. “Increasing awareness of these risks is vital to improve heart health for all.”
The American College of Cardiology (ACC) is a leading source of professional medical education for the entire cardiovascular care team. Learn more at www.ACC.org.
April 02, 2026 
