News | June 24, 2007

Women Aged 50-59 Taking Estrogen Have Reduced Levels of Coronary Artery Calcification

June 25, 2007 - A study published in a recent issue of The New England Journal of Medicine (NEJM) showed that younger menopausal women (aged 50-59) who received a standard dose of estrogen therapy had significantly less coronary artery calcification at the end of the study period compared with those taking placebo. Coronary artery calcification is a marker of plaque in the arteries and a predictor of future cardiovascular events.

The findings of the Women's Health Initiative (WHI) Coronary Artery Calcium Study are consistent with a recent re-analysis of pooled estrogen alone and estrogen plus progestin data from the WHI study, published April 4, 2007, in the Journal of the American Medical Association (JAMA). This study found no apparent increase in coronary heart disease for women who initiated hormone therapy within 10 years of menopause; and a statistically significant reduction in total mortality among women aged 50-59 in the group receiving hormone therapy compared with those in the placebo group.

"Recent analysis of the data from the WHI study have consistently clarified the initial data, to show that in the newly diagnosed population of menopausal women, estrogen therapy does not increase cardiovascular disease and that there actually is a statistically significant reduction in total mortality among women 50-59 in the group receiving hormone therapy compared with those in the placebo group," said Stephen M. Simes, president & CEO of BioSante. "These data should aid women in their consideration of hormone therapy," Simes continued.

The authors conclude, "Hormone therapy should not be initiated (or continued) for the express purpose of preventing cardiovascular disease in either younger or older postmenopausal women."

Related Content

low-dose radiation, cancer risk, mice, Berkeley National Laboratory, therapy, CT
Feature | March 23, 2015
Scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory  have uncovered new clues about...
radiation therapy, breast cancer, breath hold, heart, clinical study
News | January 19, 2015
Women who have breast cancer on their left side present a particular challenge to radiation oncologists. Studies have...
Technology | November 07, 2014
Solid Water HE is the next generation of solid water phantoms by Gammex. It is designed for both therapy and imaging...
News | October 15, 2014
The Geneva Healthcare Suite has been proven effective by clinicians at the Douglas & Nancy Barnhart Cancer Center...
Feature | July 31, 2014
July 31, 2014 — Radiation therapy may offer a promising new noninvasive alternative treatment for the millions of...
Feature | August 28, 2013
Experts have found that radiation dosage can have serious complications for patients with cancer. Cancer patients who...
Feature | May 21, 2013
Unavoidable damage caused to the heart and lungs by radiotherapy treatment of tumors in the chest region can be limited...
News | April 19, 2013
Sen. Stan Bingham and Sen. Wesley Meredith have introduced a bill in the North Carolina legislature that will require...
News | April 11, 2013
An estimated 5,000 nuclear medicine and molecular imaging professionals are expected to gather in June for the 2013...
News | April 10, 2013
Cancer survivors who had chest radiation are nearly twice as likely to die in the years after having major heart...
Overlay Init