Late-breaking clinical trials for the American College of Cardiology’s Annual Scientific Session Together with World Congress of Cardiology (ACC.23/WCC) have been announced. ACC.23/WCC will take place March 4-6, 2023, at the Ernets N. Morial Convention Center in New Orleans.
Top experts will debate and discuss the outcomes of leading-edge trials at ACC.23/WCC and explain how it all fits into current cardiology practice. There are five late-breaking clinical trial sessions, three featured clinical research sessions, and two late-breaking clinical trials (LBCT) deep dive sessions to help cardiologists stay up-to-date on the newest clinical research.
Search the sessions at virtual ACC.23meeting at https://accscientificsession.acc.org/en/Plan-Your-Program/Late-Breakers
Joint American College of Cardiology/Journal of the American College of Cardiology Late-Breaking Clinical Trials
Saturday, March 4, 9:30 – 10:30 a.m. ET
Bempedoic Acid And Cardiovascular Outcomes In Statin Intolerant Patients At High Cardiovascular Risk
TRILUMINATE Pivotal: A Landmark Randomized Clinical Trial Of Transcatheter Tricuspid Valve Edge-to-Edge Repair For Tricuspid Regurgitation
Statins To Prevent The Cardiotoxicity From Anthracyclines: The STOP-CA Trial
ACC Featured Clinical Research I
Saturday, March 4, noon – 1:15 p.m. ET
Results From A Phase 2, Double-blind, Placebo-controlled Trial Evaluating The Efficacy And Safety Of Baxdrostat In Patients With Uncontrolled Hypertension
Effect Of Myocardial Viability, Percutaneous Coronary Intervention And Functional Recovery On Clinical Outcomes In The REVIVED-BCIS2 Randomized Trial
Ischemia And Viability Imaging In Heart Failure: The Alternative Imaging Modalities In Ischemic Heart Failure Trial
Effect Of Evolocumab On Coronary Plaque Characteristics In Stable Coronary Artery Disease: A Multimodality Imaging Study (the Yellow III Study)
On-site Computed Tomography-derived Fractional Flow Reserve To Guide The Management Of Patients With Stable Coronary Artery Disease: The TARGET Randomized Trial
Joint American College of Cardiology/Journal of the American Medical Association Late-Breaking Clinical Trials
Sunday, March 5, 8 – 9:15 a.m. ET
Minimally Invasive Versus Conventional Sternotomy For Mitral Valve Repair Surgery: An Expertise Based Multicentre Randomised Controlled Trial (UK Mini Mitral)
Intravascular Imaging-guided Versus Angiography-guided Procedural Optimization In Complex Percutaneous Coronary Intervention
Transcatheter Edge-to-edge Repair Of Functional Mitral Regurgitation In Heart Failure: Final Five-year Results From The COAPT Trial
Transcatheter Versus Surgical Aortic Valve Replacement In Aortic Stenosis Patients At Low Surgical Risk: 3-year Outcomes From The Evolut Low Risk Trial
Complete Revascularization Strategies In Patients Presenting With Acute Coronary Syndromes And Multivessel Coronary Disease
Late-Breaking Clinical Trials III
Sunday, March 5, 9:45 – 11 a.m. ET
Randomized Controlled Trial Of Influenza Vaccine In Patients With Heart Failure To Reduce Adverse Vascular Events
The Effect Of Omecamtiv Mecarbil On Exercise Tolerance In Patients With Chronic Heart Failure And Reduced Ejection Fraction: METEORIC-HF
A Cluster-Randomized PRagmatic Trial Aimed At ImprOving Use Of Guideline Directed Medical Therapy In OutPatienTs With Heart Failure: PROMPT-HF
Patiromer For The Management Of Hyperkalemia In Subjects Receiving Renin-angiotensin-aldosterone System Inhibitor Medications For Heart Failure With Reduced Ejection Fraction: Results From The DIAMOND Trial
Updated Cumulative Results Of Treatment With Mavacamten From The EXPLORER-LTE Cohort Of The MAVA-LTE Study In Patients With Obstructive Hypertrophic Cardiomyopathy
Featured Clinical Research II
Sunday, March 5, 12:15 – 1:30 p.m. ET
Atrial Pacing For Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial
Association Of A Low-carbohydrate High-fat (Ketogenic) Diet With Plasma Lipid Levels And Cardiovascular Risk In A Population-based Cohort
Pharmaco-invasive Reperfusion Strategy With Half-dose Tenecteplase In Older St-elevation Myocardial Infarction Patients
Comparison Of 3-month Versus 12-month Dual Antiplatelet Therapy After Coronary Intervention Using The Contemporary Drug-eluting Stents With Ultrathin Struts And Advanced Polymer Technology: The Host-idea Randomized Clinical Trial
Safety And Efficacy Of Transcatheter Edge-to-Edge Mitral Repair In Degenerative Mitral Regurgitation: An Analysis Of The STS/ACC TVT Registry
Late-Breaking Clinical Trials Deep Dive I
Sunday, March 5, 2 – 3:15 p.m. ET
Late-Breaking Clinical Trials Deep Dive I
Clinical and Investigative Horizons
Sunday, March 5, 2 – 3:15 p.m. ET
Prediction Of Preeclampsia Using High-Sensitivity Troponin I
Outcomes In High-risk Pulmonary Embolism Patients Undergoing FlowTriever Mechanical Thrombectomy: Results From The FLAME Study
Health 360x Registry: Equitable Access To Point Of Care Decentralized Clinical Trials
Cardiovascular Disease And Mortality In Black Women Carrying The Amyloidogenic Val122ile Variant
Impact Of Remote Cardiac Device Monitoring On Green House Emissions: Data From The Global Cardiovascular Carbon Footprint (GCCF) Project
Joint American College of Cardiology/Journal of the American Medical Association Late-Breaking Clinical Trials
Monday, March 6, 8:30 – 9:45 a.m. ET
Pulsed Field Ablation Treatment In Paroxysmal And Persistent Atrial Fibrillation Patients: Acute And Long-term Outcomes From The Pulsed Af Pivotal Trial
Impact Of Heart Failure Management Using Thoracic Fluid Monitoring From A Novel Wearable Sensor: Results Of The Benefits Of Microcor (μCor™) In Ambulatory Decompensated Heart Failure (BMAD) Trial
A Novel Breakthrough In Wrist-Worn Transdermal Troponin-I-Sensor Assessment For Acute Myocardial Infarction
Efficacy And Safety Of Macitentan Tadalafil Fixed Dose Combination In Pulmonary Arterial Hypertension: Results From The Randomized Controlled Phase III A DUE Study
Coordinating Cardiology Clinics Randomized Trial Of Interventions To Improve Outcomes (COORDINATE) - Diabetes: Primary Results
Late-Breaking Clinical Trials V
Monday, March 6, 11 a.m. – 12:15 a.m. ET
Vigorous Exercise In Individuals With Hypertrophic Cardiomyopathy (HCM): Primary Results Of The Prospective, Multinational Lifestyle And Exercise In HCM (LIVE-HCM) Study
Return-to-play For Elite Level Athletes With Sudden Cardiac Death Predisposing Genetic Heart Diseases
Anticoagulation Strategies In Non-critically Ill Hospitalized Covid-19 Patients: Principal Outcomes Of The Freedom Covid Anticoagulation Trial
The STELLAR Phase III Trial: A Study Of Sotatercept In Combination With Background Therapy For The Treatment Of Pulmonary Arterial Hypertension
Efficacy And Safety Of The Oral PCSK9 Inhibitor, MK-0616, A Macrocyclic Peptide, In The Treatment Of Hypercholesterolemia: A Phase 2b Randomized Placebo-Controlled Clinical Trial
Featured Clinical Research III
Monday, March 6, 12:45– 2 p.m. ET
Lifelong Endurance Exercise And Its Relationship With Coronary Atherosclerosis
Residual Inflammatory Risk In Contemporary Statin Treated Patients: A Collaborative Analyses Of 31,197 Participants In The Prominent, Reduce-it, And Strength Trials
Comparison Between Targeted Low-Density Lipoprotein Cholesterol Level Based Versus High-Intensity Statin Therapy In Patients With Coronary Artery Disease
Evaluation Of The Mechanism Of Benefit For Dapagliflozin In Heart Failure With Preserved Ejection Fraction: An Invasive Hemodynamic Randomized Trial
Safety And Efficacy Of Virtual Care Team Guided Therapeutic Optimization During Hospitalization In Patients With HFrEF:the IMPLEMENT-HF Study
Late-Breaking Clinical Trials Deep Dive II
Monday, March 6, 2:30 – 3:45 p.m. ET
Late-Breaking Clinical Trials Deep Dive II
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April 11, 2024 
