September 17, 2010 - An aortic valve has been successfully implanted in the acute porcine model by Transcatheter Technologies GmbH (TT) using its Trinity system.
The acute in vivo study of the system has shown:
• Accurate stepwise positioning of Trinity via an antegrade transapical approach.
• Full expansion and anchoring of the Trinity valve prosthesis before the refolding of the stent.
• Complete evaluation of the fully expanded prosthesis’ function before refolding and repositioning or retrieval.
• Detachment of the stent from the catheter without changing the geometry of the deployed valve prosthesis.
• Outstanding anchoring and sealing due to the design of the stent.
• Low transvalvular gradients.
TT’s true repositioning system allows for complete expansion of the valved stent and full evaluation of prosthesis' function before repositioning, before retrieval and before final release.
“Trinity protects the fragile valve leaflets by Zero Pressure Crimping. This prevents crushing and damaging of the leaflets when the frame is folded. We expect that this will increase the lifespan of the valve prosthesis and thereby allow for implantation in even younger patients,” commented Wolfgang Goetz, M.D., Ph.D., CEO. “Our animal trials validate the feasibility of the technology in vivo. We are very proud to have achieved this significant milestone within a very short period of time.”
Transcatheter Technologies successfully closed the seed financing round in 2009 with High-Tech Gründerfonds and Seedfonds Bayern. The investment will be used for the development of a novel biological heart valve up to the proof of concept.
“Transcatheter Technologies’ valve design can solve major problems of common prosthesis. Thereby, valve implantations become an option for currently untreatable patients,” said Dr. Michael Nettersheim, of High-Tech Gründerfonds. “We are convinced that the medicinal as well as technological expertise of the team provide an ideal base for a successful corporate development.”
For more information: www.high-tech-gruenderfonds.de
November 05, 2026 
