News | CT Angiography (CTA) | January 11, 2024

Photon-Counting Detector CT Virtual Monoenergetic Images for Coronary Artery Stenosis Open configuration options

82-year-old man with calcified stenosis in left main artery who underwent coronary CTA by PCD CT

82-year-old man with calcified stenosis in left main artery who underwent coronary CTA by PCD CT. Curved multiplanar reformatted images at varying virtual monoenergetic imaging (VMI) levels (40-140 keV) show stenosis at each level. Percent diameter stenosis (PDS) decreased from 92.5% at 40 keV to 53.1% at 140 keV. Extent of calcium blooming artifacts decreased from 100.0% at 40 keV to 72.3% at 140 keV.


January 11, 2024 — According to the American Journal of Roentgenology (AJR), photon-counting detector (PCD) CT with virtual monoenergetic imaging (VMI) reconstruction can help overcome present limitations in stenosis quantification on coronary CTA.

“When performing coronary CTA by PCD CT, the selection of VMI level influences stenosis assessment in calcified and mixed plaque, thereby potentially impacting clinical decision-making,” wrote corresponding author Tilman Emrich, MD, from the department of diagnostic and interventional radiology at Germany’s University Medical Center in Mainz.

In this AJR accepted manuscript, a phantom containing two custom-made vessels (25% and 50% stenoses) underwent PCD CT acquisitions without and with simulated cardiac motion. A retrospective analysis was performed of 33 patients (7 female, 26 male; mean age, 71 years; 64 coronary artery stenoses) who underwent coronary CTA by PCD CT followed by invasive coronary angiography (ICA). Scans were reconstructed at nine VMI levels (40–140 keV). Percentage diameter stenosis was measured, and bias was determined from the ground-truth stenosis percentage in the phantom and ICA-derived quantitative coronary angiography measurements in patients. Extent of blooming artifacts was measured in the phantom and in calcified and mixed plaques in patients.

Ultimately, for coronary CTA performed by PCD CT, stenosis percentage and calcium blooming artifacts decreased with increasing VMI level in calcified and mixed plaque. Stenosis measurement exhibited lowest bias, using invasive angiography as reference, at 100, 140, and 40 keV for calcified, mixed, and non-calcified plaque, respectively.

“To our knowledge,” Emrich et al. added, “this study is the first in vivo study to investigate the influence of different VMI levels on stenosis quantification of PCD CT in comparison with ICA as the reference standard.”

For more information: www.arrs.org


Related Content

News | Cardiac Imaging

July 12, 2024 — Researchers have developed a groundbreaking method for analyzing heart MRI scans with the help of ...

Home July 12, 2024
Home
News | Cardiac Imaging

June 10, 2024 — New expert consensus from the Society of Cardiovascular Computed Tomography (SCCT) reviews previously ...

Home June 10, 2024
Home
News | Cardiac Imaging

May 10, 2024 — According to the Summa Cum Laude Award-Winning Online Poster presented during the 124th ARRS Annual ...

Home May 10, 2024
Home
News | Cardiac Imaging

April 29, 2024 — FUJIFILM Healthcare Americas Corporation, a leading provider of diagnostic and enterprise imaging ...

Home April 29, 2024
Home
News | Cardiac Imaging

April 23, 2024 — CDL Nuclear Technologies, a pioneer in advanced diagnostic solutions, is proud to announce the launch ...

Home April 23, 2024
Home
Feature | Cardiac Imaging

Cardiac positron emission tomography (PET) is growing in popularity among cardiologists because it provides the ability ...

Home March 05, 2024
Home
News | Cardiac Imaging

PLEASE NOTE: This webinar has been postponed to a later date. A new date will be posted in the coming days. On March 25 ...

Home February 29, 2024
Home
News | Cardiac Imaging

February 28, 2024 — Royal Philips, a global leader in health technology, announced major enhancements to its Image ...

Home February 28, 2024
Home
News | Cardiac Imaging

February 12, 2024 — According to the American Journal of Roentgenology (AJR), free-breathing cine-deep learning (DL) may ...

Home February 12, 2024
Home
News | Cardiac Imaging

November 16, 2023 — Cardiovascular diseases rank among the top causes of death across the world, and cardiac ...

Home November 16, 2023
Home
Subscribe Now