News | January 10, 2008

Imaging Helps Heart Modelling Research

January 11, 2008 - Imaging technologies are helping heart modellers overcome the dilemma of proving that the models really are an accurate representation of the real human heart, as demonstrated in a workshop held recently by the European Science Foundation (ESF).

Computerized in-silico models simulate the real heart and enable possible drugs and therapies to be tested without risk to people.
However, in order to create a realistic model, you need accurate and extensive data from real hearts for calibration.

“Validation of the models is very important, and was raised at the workshop,” said Blanca Rodriguez, scientific coordinator of the ESF workshop, and senior cardiac researcher at Oxford University, Europe’s leading center for cardiac modelling. “One of the problems has been that it is much easier to get experimental data from animals than humans.”

Progress in imaging techniques allows researchers to observe cardiac activity externally without the need for invasive probes. “We are now getting data at very high resolutions and that allows us to model things in more detail, with greatly improved anatomy and structure,” said Rodriguez.

One of the most important diseases being modelled is myocardial ischemia. Studying stem cell therapy to regenerate heart muscle destroyed by disease requires careful testing to eliminate possibly dangerous side effects, such as cancer and disruption of normal heart rhythms, leading to arrhythmia or irregular heart beats. Heart models “could be used to model stem cells’ behavior, and see how they are incorporated into the heart,” said Rodriguez.

Rodriguez recommends that researchers create a standard and robust software infrastructure for sharing heart models and associated data, and to define exactly how to calibrate the models more effectively from experimental data.

For more information: www.esf.org

Related Content

ASNC and SNMMI Release Joint Document on Diagnosis, Treatment of Cardiac Sarcoidosis
News | Cardiac Imaging| August 18, 2017
August 18, 2017 — The American Society of...
Houston Methodist Hospital Enters Multi-Year Technology and Research Agreement With Siemens Healthineers
News | Cardiac Imaging| August 17, 2017
Houston Methodist Hospital and Siemens Healthineers have entered into a multi-year agreement to bring cutting-edge...
CDN to Integrate Advanced Cardiac Imaging Tools From DiA Imaging Analysis
Technology | August 10, 2017
August 10, 2017 — CDN recently announced a new partnership agreement with DiA Imaging Analysis Ltd., makers of next-g
Four Blue Cross Blue Shield Companies Issue Positive Medical Policies on HeartFlow FFRct Analysis
News | FFR Catheters| August 09, 2017
HeartFlow Inc. announced that four Blue Cross Blue Shield companies have each issued a positive medical policy for the...
Left Atrial Pressure Monitor from Vectorious Medical Technologies Offers New Hope for Heart Failure Patients

On of the top stories in July was the introduction of a left atrial pressure monitor from Vectorious Medical Technologies to prevent heart failure patient hospitalizations or readmissions. Read the article"Left Atrial Pressure Monitor Offers New Hope for Heart Failure Patients."

Feature | August 01, 2017 | Dave Fornell
Aug.
Philips released a new version of its iFR system that displays FFR readings as an overlay on live angiographic, angiogram images.

Philips released a new version of its iFR system that displays hemodynamic pressure drop points in an overlay on live angiographic images, matching up the iFR readings with corresponding lesions. The system is supposed to speed diagnostic decision making and help guide percutaneous revascularization procedures. 

Feature | FFR Catheters| July 31, 2017 | Dave Fornell
The gold standard for assessing the hemodynamic significance of coronary lesions to determine if they should be revas
New PET-CT Scan Improves Detection in Rare Cardiac Condition
News | PET-CT| July 25, 2017
Using a new imaging technique that can diagnose cardiac sarcoidosis much more accurately than traditional tests,...
Sponsored Content | Videos | CT Angiography (CTA)| July 21, 2017
DAIC and ITN Editor Dave Fornell discusses some of the most innovative new computed tomography (CT) technology and tr
Cardiac CT scan showing plaque and calcification in the coronary arteries, from a Toshiba CT scanner
News | Business| July 19, 2017
July 19, 2017 — The Society of Cardiovascular Computed Tomography (SCCT) created a reimbursement fee chart for cardia
Overlay Init