News | November 23, 2011

Surgical Bypass Strongly Beats Endovascular Treatment as Preferred Treatment of Blocked Blood Vessels in the Femoral Artery

November 23, 2011 – Vascular occlusions are blocked blood vessels caused by a blood clot in an artery. Blocks in the femoral artery are particularly problematic, and vascular surgeons continue to research and debate on the best methods to treat these clots. Results from the THRUPASS Study Group’s randomized controlled trial comparing superficial femoral artery (SFA) lesion treatment with either endoluminal polytetrafluoroethylene (PTFE) thrupass (Viabahn) or with surgical PTFE bypass were presented to attendees at the 38th Annual VEITH symposium in New York City by Mauri J.A. Lepantalo, M.D., Helsinki University Central Hospital, Helsinki, Finland.

In the study, the SFA lesions of the patients were 5-25 cm occlusions, with a mean length of 11.4 cm. The patients were followed for three years by physical exam, duplex ultrasound or other imaging modalities. The endpoint of greatest interest was primary patency, followed by secondary patency, functional success, costs and quality of life. Lepantalo said, “The goal had been to enroll 60 patients in each arm. However, the trial was prematurely terminated due to results at the interim analysis, when only 44 patients had been enrolled. There was a significant patency difference in favor of surgical bypass over endovascular thrupass (95 percent versus 44 percent).”

Lepantalo noted that this was a difficult trial to enroll patients, because the investigators were looking carefully for comparable lesions to which to randomize treatment. “The real problem with comparing different modes of treatment for lower limb ischemia is in controlling for the disease, to ensure that the comparisons are among patients with the same lesions. This is compounded by the fact that different physicians interpreting the same lesions will characterize them differently,” said Lepantalo.

In this study, the results showed that treatment of superficial femoral artery occlusions should be done by PTFE bypass rather than by PTFE thrupass, as the later method leads to a worse early outcome.

For more information: www.VEITHpress.org

Related Content

Surgical Site Infection (SSI) prevention remains a high priority for cardiac surgeons whose heroic efforts can be thwarted by infection. No matter how skilled a cardiac surgeon or how successful a surgery, when an SSI sets in, patients can find themselves fighting for their lives. While not unique to cardiovascular surgery, post-operative infections have severe repercussions for recovering heart surgery patients. Unfortunately, even with SSI prevention methods implemented, SSIs remain as common as 5% in car

Getty Images

Feature | Cardiovascular Surgery | June 24, 2021 | By Noam Emanuel, Ph.D.
Surgical Site Infection (SSI) prevention remains a high priority for cardiac surgeons whose heroic efforts can be thw
The Transmedics Organ Care System (OCS) Heart, or “Heart in a Box,” enables transplant surgeons to travel to much farther destinations to procure transplant hearts by acting as a miniature intensive care unit that keeps the heart alive.

The Transmedics Organ Care System (OCS) Heart, or “Heart in a Box,” enables transplant surgeons to travel to much farther destinations to procure transplant hearts by acting as a miniature intensive care unit that keeps the heart alive.

News | Cardiovascular Surgery | April 05, 2021
April 5, 2021 — Smidt Heart Institute transplant surgeons...
Closing access to the radial artery after harvesting a section of the artery for a coronary artery bypass graft (CABG). Photo by Getty Images. #ACC20 #ACC2020

Closing access to the radial artery after harvesting a section of the artery for a coronary artery bypass graft (CABG). Photo by Getty Images.

News | Cardiovascular Surgery | March 30, 2020
March 30, 2020 — Patients undergoing coronary bypass graft (CAGB) surgery lived longer and had better outcomes when s
The LivaNova Heater-Cooler System 3T helps open heart surgery patients, but can pose an infection risk if not properly cared for.

The LivaNova Heater-Cooler System 3T helps open heart surgery patients, but can pose an infection risk if not properly cared for.

News | Cardiovascular Surgery | February 27, 2020
February 27, 2020 — The U.S.
Michigan Hospital Improves Post-CABG Outcomes Using Proactive Amiodarone Protocol
News | Cardiovascular Surgery | October 23, 2019
Proactive administration of amiodarone to patients recovering from a common heart surgery shows promise in preventing...
Gore Block Grant Supports SVS Quality Programs
News | Cardiovascular Surgery | October 17, 2019
W. L. Gore & Associates Inc. will support a new Society for Vascular Surgery (SVS) initiative to advance patient...
Heart and Lung Surgery Patients May Be at High Risk for Opioid Dependence

Image courtesy of the American Heart Association

News | Cardiovascular Surgery | August 22, 2019
The amount of opioids prescribed for patients after heart and lung surgery has a direct relationship with the risk for...
Keck School of Medicine Promotes Patient Diversity in Cardiac Surgery Clinical Trials
News | Cardiovascular Surgery | July 26, 2019
A highly competitive $4.5 million grant from the National Institutes of Health (NIH) National Heart, Lung and Blood...
Google Doodle Celebrates Coronary Artery Bypass Graft Pioneer René Favaloro
News | Cardiovascular Surgery | July 12, 2019 | Jeff Zagoudis, Associate Editor
Internet search engine giant Google unveiled a new Doodle on its homepage Friday, July 12, celebrating the life and...
Open Heart Surgery Outperforms Stents in Patients With Multivessel Disease
News | Cardiovascular Surgery | May 03, 2019
Coronary artery bypass grafting (CABG) surgery may be the best treatment option for most patients with more than one...