A new Phase 2 clinical trial looks to confirm the efficacy and safety of Thrombolytic Science LLC’s (TSI) sequential dual-treatment regimen of low-dose tissue plasminogen activator (tPA) and HisproUK (TSI’s mutant prourokinase [proUK]) in ischemic stroke patients. The study follows a recently completed Phase 1 study that confirmed the safety and tolerability of TSI’s regimen in healthy volunteers (n=26).

Tafamidis is the first treatment to improve survival and reduce hospitalizations in a rare heart condition called transthyretin amyloid cardiomyopathy, according to late-breaking research presented in a Hot Line Session at the European Society of Cardiology (ESC) Congress 2018 and published in the New England Journal of Medicine.

W. L. Gore & Associates Inc. (Gore) announced the acquisition of Pipeline Medical Technologies Inc., a privately held medical technology company focused on advancing chordal repair for degenerative mitral regurgitation (DMR) via a transcatheter procedure.