News | August 15, 2013

Tyrx Announces First U.S. Implantation of AigisRx R Fully Bioresorbable Antibacterial Envelope

Procedure performed at Vanderbilt Heart and Vascular Institute

Tyrx AIGISRx R Fully Resorbable Antibacterial Envelope Implantation

August 15, 2013 — The first implantation of Tyrx Inc.’s new AigisRx R Fully Resorbable Antibacterial Envelope has taken place at the Vanderbilt Heart and Vascular Institute in Nashville, Tenn., by Christopher R. Ellis. The AigisRx R Antibacterial Envelope received U.S Food and Drug Administration (FDA) clearance on May 20, 2013.

“We have been pleased with the performance of the first generation partially resorbable AigisRx,” stated Ellis, cardiac electrophysiologist and assistant professor of medicine at the Vanderbilt Heart and Vascular Institute. “Now with the second generation AigisRx R, we have the added benefit of it being fully bioresorbable, which will shorten procedure times required on potential future interventions.”

The AigisRx R device is a fully bioresorbable, antibacterial mesh envelope, intended to hold cardiac implantable electronic devices (CIEDs), such as pacemakers and implantable cardioverter defibrillators (ICDs) securely in place to provide a stable environment when implanted in the body. The AigisRx R contains the antimicrobial agents rifampin and minocycline, which are released locally into the tissue to help reduce surgical site infections (SSIs) associated with CIED implantation. Multiple studies have shown that patients at high risk for CIED infection who are implanted with the AigisRx Antibacterial Envelope had 70 percent to 100 percent fewer device infections than similar patients who did who did not receive the AigisRx.

Vanderbilt Heart and Vascular Institute recently performed a matched cohort study to compare the incidence of CIED infection in patients receiving a CIED with or without an AigisRx Antibacterial Envelope. After a minimum of 90 days of follow-up, the incidence of CIED infection was significantly lower in the group that received the AigisRx, compared to those that did not (0.4% vs. 3%, OR = 0.13 [0.02-0.95],p=0.04). There were 87 percent fewer CIED infections in patients who received the AigisRx, compared to those who did not. (Kolek et al.Pacing Clin Electrophysiol. 2013;36(3);354-361).

“We are very pleased to have the first U.S. AigisRx R implantation at the Vanderbilt Heart and Vascular Institute,” commented Robert White, Tyrx president and CEO. “The AigisRx R provides physicians and facilities with a key tool in preventing surgical site infections and in helping to lower the hospital costs associated with them. Two recent studies indicate that hospitals can save $102,000 for every 100 high-risk patients that receive the AigisRx Antibacterial Envelope.”

For more information: www.tyrx.com

Related Content

New Multi-Center Research Effort to Focus on Early Life Origins of Heart Health
News | Congenital Heart| June 23, 2017
Heart health in children will be the focus of three closely synergistic research projects and an integrated...
Feature | EP Lab| June 22, 2017 | Dave Fornell
Electrophysiology (EP) technology has been advancing rapidly the past few years with new ablation tools to improve ar
Pacemakers and Other Cardiac Devices Can Help Solve Forensic Cases
News | Pacemakers| June 20, 2017
Pacemakers and other cardiac devices can help solve forensic cases, according to a study presented at the European...
BioTrace Medical's Tempo Lead Shows Stability and Safety in Real-World Performance
News | Leads Implantable Devices| June 20, 2017
BioTrace Medical Inc. announced that the company’s Tempo Temporary Pacing Lead was featured in an oral presentation and...
BioImage-2 Study to Investigate Atherosclerotic Disease Progression
News | Cardiovascular Ultrasound| June 20, 2017
Mount Sinai Heart and BioImage-2 LLC recently announced the start of the BioImage-2 study investigating the progression...
News | June 12, 2017
June 12, 2017 – Med Alliance announced completion on schedule of patient enrollment in the first-in-man (FIM) study o
Sponsored Content | Videos | Business| June 06, 2017
Andrea Natale, M.D., FACC, FHRS, FESC, executive medical director, Texas Cardiac Arryhthmia Institute at St.
Biosense Webster's multi-electrode RF ablation balloon

The most popular technology in May was the first data released on Biosense Webster's multi-electrode RF ablation balloon with irrigation. The system allows operators to change the energy levels of each electrode to avoid damaging sensitive underlying critical structures like the esophagus or phrenic nerve.

Feature | June 01, 2017 | Dave Fornell
June 1, 2017 — Here is the list of the most popular pieces of content on the Diagnostic and Interventional Cardiology
Infab Introduces Revolution Lead Aprons
Technology | Radiation Dose Management| June 01, 2017
June 1, 2017 — Infab Corp.
Sponsored Content | Videos | Implantable Cardioverter Defibrillators (ICD)| June 01, 2017
Lucas Boersma, M.D., Ph.D., FESC, St.
Overlay Init