February 12, 2015 — Medi-Lynx Cardiac Monitoring LLC and Medicalgorithmics have announced their participation in a research project investigating the impact of lifestyle modification on ablation outcome in atrial fibrillation (ISOLATE). Medicalgorithmics’ PocketECG cardiac monitoring system will be used for collecting and analyzing the electrocargiogram (ECG) data in the project.
The research started in August 2014, financed by Texas Cardiac Arrhythmia Research Foundation. It will evaluate the impact of aggressive lifestyle modification, in terms of calorie-controlled diet and supervised exercise, on outcomes of catheter ablation in overweight and obese patients with atrial fibrillation. The hypothesis states that weight loss and management by adoption of a strict diet and exercise regimen improves the chances of freedom from recurrence following catheter ablation.
The PocketECG system recognizes the morphology of each individual heartbeat and allows differentiating between normal and abnormal heartbeats including ventricular ectopy, supraventricular ectopy, aberrated supraventricular beats, artifact, etc. This functionality combined with the capability of streaming the continuous ECG for many weeks provides reliable Heart Rate Variability statistics over an extended monitoring period. The system also has the ability to calculate detailed arrhythmia statistics for extended monitoring sessions and to identify HRV changes and morphology of each individual QRS complex.
The study’s eligible group is overweight or obese adult patients with a diagnosis of atrial fibrillation undergoing first catheter ablation at least three months after the enrollment. Supervised and monitored exercise will be conducted in St. David's Cardiac Rehabilitation for at least three months before ablation. After ablation, patients will continue an individualized home-exercise program for one year.
For more information: www.medicalgorithmics.com
November 12, 2025 
