October 17, 2007 - Compared to bare metal stents, in patients with acute myocardial infarction, sirolimus-eluting stent (SES) implantation aggravates endothelial vasomotor dysfunction in the infarct-related coronary artery, Japanese researchers report in the October 2nd issue of the Journal of the American College of Cardiology.
Kiyotaka Kugiyama, M.D., and colleagues at the University of Yamanashi, Chuo City note that drug-eluting stents reduce restenosis rates and revascularization but may impair recovery from reperfusion-induced endothelial injury.
