News | April 07, 2008

CAD Risk Less, Endothelial Function Improved in Cleaner Environment

April 8, 2008 - A study using Itamar Medical's Endo-PAT2000, an FDA-cleared device used to assess endothelial function, found that when indoor air particles are reduced in a controlled study environment, endothelial function, an indicator of cardiovascular health, significantly improves.

Itamar Medical's Endo-PAT2000 was used for evaluating the effect of high-efficiency particulate air (HEPA) filters on endothelial function in healthy elderly patients residing close to major roads. Vaclavik et al. found that air filtration significantly improved endothelial function in the study subjects (Vaclavik et al. Indoor Particles Affect Vascular Function in the Aged. American Journal of Respiratory and Critical Care Medicine 2008; Vol 177. pp. 419-425). Endothelial function is an important indicator of vascular health, so much so that endothelial dysfunction has been described as the "ultimate risk of risk factors" (Bonetti et al., Endothelial Dysfunction: A Marker of Atherosclerotic Risk, ATVB, 2003;23;168-175).

Both short-term and long-term exposure to ambient levels of particulate are associated with increased fatalities related to respiratory and cardiovascular disease. Researchers in the study believe endothelial dysfunction, which is a strong predictor of adverse cardiovascular conditions, may be the source of this increase in respiratory and cardiovascular diseases.

For more information: www.itamar-medical.com

Related Content

Medtronic Announces Global Resolute Onyx DES One-Month DAPT Study
News | Antiplatelet and Anticoagulation Therapies| August 18, 2017
Medtronic plc announced a global randomized clinical trial that will evaluate one-month dual antiplatelet therapy (DAPT...
Abbott Initiates XIENCE Short DAPT Clinical Trial
News | Antiplatelet and Anticoagulation Therapies| August 03, 2017
Abbott recently announced the first patient has been enrolled in a clinical study evaluating the short-term use of...
Onyx DES 2.0 mm stent meets primary endpoints in small vessels
News | June 12, 2017
June 12, 2017 – The Medtronic Resolute Onyx Drug-Eluting Stent (DES) met its primary endpoint of target lesion failur
First Pennsylvania Patient Treated in LEADERS FREE II Trial of BioFreedom Drug-Coated Stent
News | Stents Drug Eluting| May 12, 2017
PinnacleHealth CardioVascular Institute enrolled the first patient in Pennsylvania in a trial assessing the safety and...
Resolute Onyx DES, drug eluting stent, medtronic, gains FDA approval
Technology | Stents Drug Eluting| May 01, 2017
May 1, 2017 — The U.S.
Sponsored Content | Videos | Stents Drug Eluting| May 01, 2017
This video, provided by Medtronic, demonstrates the Resolute Onyx coronary stent.
Biosensors, BioFreedom drug-coated stent, LEADERS FREE II IDE trial, first patient, U.S. pivotal study
News | Stents Drug Eluting| March 03, 2017
Biosensors International Group Ltd. announced in February enrollment of the first patient in LEADERS FREE II, its new...
CeloNova Cobra Pzf stent
Technology | Stents| March 02, 2017
March 2, 2017 — The U.S. Food and Drug Administration (FDA) cleared CeloNova BioSciences Inc.
Synergy stent, abluminal polymer DES, bioresorbable polymer DES, bioresorbable polymer metallic stent

The Synergy stent is the first FDA cleared drug-eluting stent to use a bioresorbable polymer drug carrier. When the polymer dissolves after about four months, the devices become a bare metal stent. The technology is supposed to reduce the rate of late stent thrombosis due to vessel inflammation caused by durable polymers.

Feature | Stents Bioresorbable| January 17, 2017 | Dave Fornell
One of the big advancements in drug-eluting stent (DES) technology has been the development of bioresorbable polymers
OCT, intravascular imaging, stent, good stent apposition on vessel wall, TRANSFORM-OCT study

An OCT image showing good stent strut apposition against the vessel wall.

News | Stents| January 13, 2017
January 13, 2017 — Results from TRANSFORM-OCT, a prospective, randomized trial using optical coherence tomography (OC
Overlay Init