News | Stem Cell Therapies | October 24, 2017

Ncardia Signs License Agreement with First Pharmaceutical Partner for Disease Modeling Patent Portfolio

Agreement gives Roche non-exclusive, worldwide license to key Ncardia disease modeling patents for development of stem cell-derived cells and disease models for the discovery and development of novel drug candidates

October 24, 2017 — Roche and Ncardia have reached a broad licensing agreement whereby Roche and its affiliate companies gain access to key disease modeling patents from Ncardia.

Ncardia was recently formed through the merger of Axiogenesis and Pluriomics. The two companies have pioneered the development of stem cell-derived cells for drug discovery and safety, and in particular have advanced disease and tissue modeling applications.

The Ncardia patent portfolio consists of several granted patents in Europe, the United States and Japan. The drug screening and disease modeling technology not only involves patient iPSC cells, but induction of the disease phenotype can also be achieved through genetic manipulation, mRNA or siRNA transfection or through chemical or physical induction.

Roche has now obtained a non-exclusive, worldwide license to the key Ncardia disease modeling patents claiming the use of stem cell-derived cells and disease models for the discovery and development of novel drug candidates. The financial terms of the agreements are not disclosed.

For moreinformation: www.ncardia.com

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Coronary CT angiography images of a coronary artery depicting the perivascular fat attenuation index (FAI) before and after biologic therapy at one-year follow-up. Patients had excellent response to biologic therapy, showing clear reductions in the inflammation in plaques that cause heart attacks and stokes. Image from the Oxford Academic Cardiovascular CT Core Lab and Lab of Inflammation and Cardiometabolic Diseases at NHLBI.

Coronary CT angiography images of a coronary artery depicting the perivascular fat attenuation index (FAI) before and after psoriasis biologic drug therapy at one-year follow-up. Patients had excellent response to biologic therapy, showing clear reductions in the inflammation in plaques that cause heart attacks and stokes. Image from the Oxford Academic Cardiovascular CT Core Lab and Lab of Inflammation and Cardiometabolic Diseases at NHLBI.

 

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