News | January 23, 2012

Pregnant Women With Life-Threatening Blood Clots Should Receive Aggressive Treatment

January 23, 2012 — Pregnant women who develop dangerous blood clots in the leg often forgo the most effective treatment for fear of harming the baby. Yet treatment to remove the clot is not only safe, it can prevent serious problems, including death, suggests research being presented at the 24th International Symposium on Endovascular Therapy (ISET).

Deep vein thrombosis (DVT) – a blood clot that forms deep in the thigh – is four to six times more common in pregnant women than those who are not pregnant. A smaller blood clot can break off and travel to the lung artery causing a pulmonary embolism. When DVT is not treated early and effectively, the clot can become permanent, causing lifelong pain and blood flow problems. The most effective treatments include the minimally invasive delivery of clot-dissolving drugs directly to the clots to break them up, or surgery.

The study included 11 pregnant women with DVT. Nine were treated with minimally invasive techniques by guiding a tiny tube called a catheter to the site of the clot to deliver a bath of clot-dissolving drugs, and two had surgery to remove the clot. Treatment successfully broke up the clot in all cases. All but one of the pregnancies resulted in a successful birth. One woman in her second trimester miscarried a week after treatment. The woman suffers from antiphospholipid antibody syndrome, which causes the blood to clot abnormally and increases the risk of miscarriage, so the condition likely was the cause of her miscarriage in this case as well, researchers said. Three of the women had successful subsequent pregnancies.

Pregnant women who develop DVT are typically treated less aggressively with blood thinners, which rarely clear the clot.

“Pulmonary embolism is the second most frequent cause of death in pregnant women in North America and the United Kingdom,” said Anthony Comerota, M.D., director of the Jobst Vascular Center at The Toledo Hospital, Ohio. “Physicians should use more effective treatment to prevent these women from having serious life-long problems that can affect their ability to care for their children.”

For more information: www.iset.org

Related Content

Corindus Announces First Patient Enrolled in PRECISION GRX Registry
News | Robotic Systems| September 18, 2017
September 18, 2017 — Corindus Vascular Robotics Inc.
Two-Year ILLUMENATE Trial Data Demonstrate Efficacy of Stellarex Drug-Coated Balloon
News | Drug-Eluting Balloons| September 18, 2017
Philips announced the two-year results from the ILLUMENATE European randomized clinical trial (EU RCT) demonstrating...
Sentinel Cerebral Protection System Significantly Reduces Stroke and Mortality in TAVR
News | Embolic Protection Devices| September 18, 2017
September 18, 2017 – Claret Medical announced publication of a new study in the...
Marijuana Associated With Three-Fold Risk of Death From Hypertension
News | Hypertension| September 14, 2017
Marijuana use is associated with a three-fold risk of death from hypertension, according to research published recently...
Peter Schneider, M.D. presents late breaking clinical trial results at VIVA 17 in Las Vegas. Panelists (l to r) Krishna Rocha-Singh, M.D., Sean Lyden, M.D., John Kaufman, M.D., Donna Buckley, M.D.

Peter Schneider, M.D. presents late breaking clinical trial results at VIVA 17 in Las Vegas. Panelists (l to r) Krishna Rocha-Singh, M.D., Sean Lyden, M.D., John Kaufman, M.D., Donna Buckley, M.D.

Feature | Cath Lab| September 14, 2017
September 14, 2017 — Here are quick summaries for all the key late-breaking vascular and endovascular clinical trials
Medtronic Announces Japanese Regulatory Approval for In.Pact Admiral Drug-Coated Balloon
News | Drug-Eluting Balloons| September 13, 2017
Medtronic plc announced that the In.Pact Admiral Drug-Coated Balloon (DCB) received approval from the Japanese Ministry...
PQ Bypass Reports Positive Results for Detour System in Patients With Long Femoropopliteal Blockages
News | Peripheral Artery Disease (PAD)| September 13, 2017
A subset analysis of the DETOUR I clinical trial showed promising safety and effectiveness results of PQ Bypass’ Detour...
News | Cardiac Diagnostics| September 12, 2017
Contracting shingles, a reactivation of the chickenpox virus, increases a person’s risk of stroke and heart attack,...
Vascular screening for abdominal aortic aneurysm, peripheral artery disease and hypertension during the VIVA Study in Denmark

Vascular screening for abdominal aortic aneurysm, peripheral artery disease and hypertension during the VIVA Study. Photo credit: Lisbeth Hasager Justesen, Viborg Hospital.

News | Cardiac Diagnostics| September 12, 2017
September 12, 2017 — A new screening program for vascular disease saves one life for every 169 men assessed, accordin
News | Pharmaceuticals| September 12, 2017
September 12, 2017 — Inclisiran lowers low-density lipoprotein (LDL, or “bad”) cholesterol for up to one year in pati
Overlay Init