News | June 18, 2009

Study Looks at Impact of the Definition Utilized on Contrast-Induced Nephropathy in PCI

June 18, 2009 - Several definitions have been used to assess rates of contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary intervention (PCI), and a study this week in the American Journal of Cardiology (Vol. 103, Issues 12, pages 1,657-1,662, June 15, 2009), underlines the need to standardize these definitions.

The study examined if the definition influences observed rates of CIN. The study concluded CIN ranged in frequency from 3.3 to 10.5 percent depending on the definition used and was not associated with in-hospital mortality or substantial morbidity, such as dialysis. The wide variation in CIN and its lack of association with adverse outcomes underscore the need for a standardized, clinically relevant definition.

The Oxilan Registry was the first prospective analysis of the efficacy and safety of ioxilan (low-osmolar and low-viscosity contrast medium), including rates of CIN assessed by multiple definitions, in PCI. From July 2006 to June 2007, consecutive patients undergoing PCI using ioxilan were enrolled. Serum creatinine (SCr) and estimated glomerular filtration rate (eGFR) were assessed at baseline and three to five days after PCI. CIN was defined as SCr increase ?0.5 mg/dl, eGFR decrease ?25 percent, SCr increase ?25 percent or the composite.

Of 400 patients (age 62 ± 11 years), 19 percent were women, 37 percent were diabetic, 22 percent were anemic and 8 percent had a history of congestive heart failure. Baseline SCr was 1.12 ± 0.3 mg/dl, and 24 percent had an eGFR

Hospitalization was prolonged in 3.4 percent of patients with CIN and none required dialysis. There were no deaths or severe allergic reactions. Non–ST-elevation myocardial infarction and repeat revascularization each occurred in 0.8 percent.

For more information: www.ajconline.org

Related Content

Mentice and Siemens Healthineers Integrate VIST Virtual Patient With Artis Icono Angiography System
Technology | Angiography | June 24, 2019
Siemens Healthineers and Mentice AB announced the collaboration to fully integrate Mentice’s VIST Virtual Patient into...
Medis QAngio XA 3D Receives FDA 510k Clearance
Technology | Angiography | June 04, 2019
Medis Medical Imaging Systems B.V. has received clearance from the U.S. Food and Drug Administration for its QAangio XA...
iSchemaView Launches RAPID Angio
Technology | Angiography | March 01, 2019
iSchemaView announced the release of RAPID Angio, a complete neuroimaging solution for the angiography suite that...
Videos | Angiography | February 08, 2019
This is an example of an arterial venous malformation (AVM) in the brain imaged on a ...
Canon Medical Debuts Alphenix 4-D CT at RSNA 2018
Technology | Angiography | February 06, 2019
Canon Medical Systems USA Inc. recently introduced a new angiography configuration featuring its Alphenix Sky + C-arm...
Canon Medical Systems Launches Alphenix Interventional Imaging Line
Technology | Angiography | February 04, 2019
Canon Medical Systems USA recently introduced its next generation of interventional systems – the Alphenix platform....
An example of multimodality image fusion with live angiography to enhance soft-tissue visualization during complex procedures. This example is from Siemen's new TrueFusion software released in 2018. Advances in angiography imaging.

An example of multimodality image fusion with live angiography to enhance soft-tissue visualization during complex procedures. This example is from Siemen's new TrueFusion software released in 2018. 

Feature | Angiography | January 28, 2019 | Dave Fornell, Editor
There are a few recent trends in X-ray...
Philips Launches Azurion With FlexArm
Technology | Angiography | January 17, 2019
Philips announced the launch of Azurion with FlexArm, designed to enhance positioning flexibility for image-guided...
Videos | Angiography | December 12, 2018
This is a quick walk around of a GE Healthcare Image Guided System (IGS) angiography system cath lab room display at
Shimadzu Medical Systems Teams With Change Healthcare Cardiology
News | Angiography | October 17, 2018
Shimadzu Medical Systems USA and Change Healthcare have entered a partnership through which Shimadzu will offer Change...
Overlay Init