August 29, 2011— The echocardiographic response (reduction of left ventricular end-systolic volume), evaluated at six months follow-up, proved a better predictor of long-term mortality than clinical status improvement in a large population of cardiac resychronization therapy (CRT) patients. Therefore, assessment of occurrence of left ventricular reverse remodeling at mid-term follow-up may be an adequate surrogate endpoint in heart failure patients treated with CRT.
