January 4, 2022 —  The U.S. Food and Drug Administration (FDA) has cleared Novartis' inclisiran (Leqvio), the first  small interfering RNA (siRNA) therapy to lower low-density lipoprotein cholesterol (LDL-C) with two doses a year, after an initial dose and one at three months. The drug provides effective and sustained LDL-C reduction of up to 52% vs. placebo for certain people with atherosclerotic cardiovascular disease (ASCVD) on maximally tolerated statin therapy.[1,2]

January 3, 2022 — The following is a list of the 2021 news stories from the European Society of Cardiology (ESC) releases that saw the most  media coverage worldwide. These include lifestyle stories and the latest science published in ESC journals and presented at ESC Congress. Heart failure was also a hot topic, including ESC Guidelines on heart failure management.

January 3, 2022 — The U.S. Food and Drug Administration (FDA) recently revised its Janssen COVID-19 Vaccine Fact Sheets with a contraindication for any individuals with a history of thrombosis with thrombocytopenia following the Janssen COVID-19 vaccine or any other adenovirus-vectored COVID-19 vaccine.

The fact sheets now include updated information about the risk of thrombosis with thrombocytopenia syndrome (TTS) following vaccination. The updates Occurred December 14.

Wishing you a healthy and happy New Year from the DAIC team. Look for many exciting new changes to come in 2022!


December 26, 2021 — Here is a list of the most popular videos on the DAIC website from the past year in 2021 based on reader pageviews. Browse more videos.

1. VIDEO: ECMO Hemodynamic Support Effective in Sickest COVID-19 Patients 12,000 — Interview with Ryan Barbaro, M.D


December 23, 2021 — An interdisciplinary research team from the University of Göttingen and Hannover Medical School (MHH) has detected significant changes in the heart muscle tissue of people who died from Covid-19. Damage to lung tissue has been the research focus in this area for some time and has now been thoroughly investigated.


COVID-19 was the single biggest topic readers came to DAIC for information in 2021, resulting in more than 300,000 pageviews just for this one topic. Here is a list of the most accessed COVID content in the past year.

Kawasaki-like Inflammatory Disease Affects Children With COVID-19

Addressing Atrial Fibrillation in the World of COVID-19



Here is a list of the top 25 stories in 2021 on the Diagnostic and Interventional Cardiology (DAIC) website based on reader pageviews. DAIC had more than 3.55 million pageviews in 2021.

1. Addressing Atrial Fibrillation in the World of COVID-19

2. The Long-term Cardiovascular Impact of COVID-19


December 16, 2021 — MVP Health Care and The University of Vermont Health Network recently announced their joint Medicare Advantage Plan, called UVM Health Advantage, will offer older adults in Northern New York and Vermont support for their two biggest health concerns: heart disease and diabetes.


In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease. The study, published in the journal Nature,[1] was led by the Global Lipids Genetics Consortium.


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