September 12, 2017 — Inclisiran lowers low-density lipoprotein (LDL, or “bad”) cholesterol for up to one year in patients with high cardiovascular risk and elevated LDL cholesterol, according to late-breaking results from the ORION 1 trial presented at the 2017 European Society of Cardiology (ESC) Congress.

September 12, 2017 — Very aggressive reduction of LDL-cholesterol to ultra-low levels was associated with progressively fewer cardiovascular events and appears to pose no safety concerns in patients with stable atherosclerotic cardiovascular disease over 2.2 years of follow-up, according to a new analysis of the FOURIER Trial. The results were presented at the 2017 European Society of Cardiology (ESC) Congress and published in the Lancet.

September 12, 2017 — The IL-1β inhibitor canakinumab lowers the risk of cardiovascular disease and lung cancer risk by reducing inflammation, according to late-breaking results from the CANTOS trial presented at the 2017 European Society of Cardiology (ESC) Congress and published in the New England Journal of Medicine (NEJM).


September 12, 2017 — Rivaroxaban plus aspirin improves survival and reduces stroke and heart attack in patients with stable coronary or peripheral artery disease, according to late-breaking results from the COMPASS Trial presented in a Hot Line late-breaking clinical trials session at the 2017 European Society of Cardiology (ESC) Congress and published in the New England Journal of Medicine (NEJM).


Hoag Memorial Hospital Presbyterian recently became the first hospital in Orange County, Calif., to install the Siemens Somatom Force computed tomography (CT) scanner. The Somatom Force allows radiologists to obtain higher-quality images faster, more efficiently and with less radiation than older-generation CT scanners.


September 12, 2017 – The Cardiovascular Research Foundation (CRF) announced the promotion of Juan F. Granada, M.D., as the foundation’s president and chief executive officer (CEO). Granada was also appointed to CRF’s Board of Directors. A renowned leader in cardiology, he joined CRF in 2007 and served as executive director and chief innovation officer at the CRF Skirball Center for Innovation. He is also an assistant professor of medicine at Columbia University College of Physicians and Surgeons. 


September 11, 2017 — According to the latest market study released by Technavio, the global electrophysiology therapeutic devices market is expected to grow at a compound annual growth rate (CAGR) of more than 9 percent between 2017 and 2021.


November 9, 2017 — From numerous high-quality submissions, Transcatheter Cardiovascular Therapeutics (TCT) has selected 12 late-breaking clinical trials and 16 first report Investigations that are guaranteed to impact patient care and future directions in cardiovascular technologies. 
 
Monday, October 30 - Main Arena I
Late-Breaking Clinical Trials 1

Merck and researchers in the Clinical Trial Service Unit at the University of Oxford announced the publication and presentation of results from the REVEAL outcomes study of anacetrapib, Merck’s investigational cholesteryl ester transfer protein (CETP) inhibitor. In the study of 30,449 patients with atherosclerotic vascular disease receiving LDL-C lowering treatment with atorvastatin, anacetrapib significantly reduced the risk of major coronary events (composite of coronary death, myocardial infarction or coronary revascularization) by 9 percent relative to placebo (10.8% vs. 11.8%, respectively; P=0.004). The safety of anacetrapib was generally consistent with data from earlier trials of the drug. However, a sub-study also showed that anacetrapib accumulates in adipose tissue with prolonged dosing.

September 11, 2017 — Veniti Inc. announced that Boston Scientific will distribute the Vici Venous Stent under a limited global distribution agreement. The terms of the agreement and specific regions and countries involved were not disclosed.

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