Videos | Coronavirus (COVID-19) | September 29, 2020

VIDEO: Overview of Multisystem Inflammatory Syndrome in Children (MIS-C) in COVID-19 Exposed Children

Deepika Thacker, M.D., a pediatric cardiologist with Nemours Children’s Health System, Wilmington, Del., helped discover one of the first cases of multisystem inflammatory syndrome in children (MIS-C) in the United States. She explains how they treated the first and subsequent pediatric patients with the COVID-19 related syndrome. Read more about the first case of MIS-C Nemours treated in the article Case Study Describes One of the First U.S. Cases of MIS-C.

The dangerous Kawasaki Disease-like syndrome occurs in a small number of children exposed to the COVID-19 (SARS-CoV-2) virus. MIS-C is an autoimmune reaction where the COVID appears asymptomatic, but the immune system overeacts to the virus and begins attacking health tissues in the body. It causes severe causes inflammation of the heart, lungs and other vital organs.


CDC Reports 800 U.S. Children Diagnosed With MIC-C

The Centers for Disease Control and Prevention (CDC) reported as of Sept. 10, 2020, there have been 792 confirmed cases in the United States of the rare MIS-C condition in children that is linked to COVID-19.

The agency also reported there have been 16 deaths reported from the MIS-C cases reported in 42 states, New York City and Washington, D.C., as of Sept. 3. Nearly all cases of MIS-C occurred in children who tested positive for the new coronavirus, while the remainder were in children who were around a person with COVID-19.

The CDC report also gave the following statistics:

   • Most cases are in children between the ages of 1 and 14 years, with an average age of 8 years.
   • Cases have occurred in children from <1 year old to 20 years old.
   • More than 70% of reported cases have occurred in children who are Hispanic/Latino (276 cases) or non-Hispanic Black (230 cases).
   • 99% of cases (783) tested positive for SARS CoV-2, the virus that causes COVID-19. The remaining 1% were around someone with COVID-19.
   • Most children developed MIS-C 2-4 weeks after infection with SARS-CoV-2.
   • Slightly more than half (54%) of reported cases were male.

Find additional CDC statistics on U.S. MIS-C cases


Related Content on MIS-C:

Kawasaki-like Inflammatory Disease Affects Children With COVID-19

Case Study Describes One of the First U.S. Cases of MIS-C

NIH-funded Project Wants to Identify Children at Risk for MIS-C From COVID-19

New Study Looks at Post-COVID-19 Emerging Disease in Children

Cardiac MRI Aids Evaluation of Children With Multisystem Inflammatory Syndrome (MIS-C) Associated With COVID-19

The Cardiovascular Impact of COVID-19

VIDEO: Example of a Multisystem Inflammatory Syndrome in Children (MIS-C) Pediatric Echocardiogram

NIH-funded Project Wants to Identify Children at Risk for MIS-C From COVID-19


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