Hicham Skali, M.D., a staff cardiologist and member of the Non-invasive Cardiovascular Imaging...
Single-photon emission computerized tomography (SPECT) imaging is a nuclear imaging technology (also referred to as molecular imaging) that produces images showing how organs work. The is eanbled by the use of radiotracers, usually attached to sugars. The cells in the body metabolize the sugar and the nuclear images show areas of high and low sugar uptake. This allows imaging of ischemia or infarct in the heart or other organs, or areas of high sugar uptake caused by cancers, which usually have a much higher metabolism than health cells.
This is 4MD’s cardiac nuclear imaging analysis software, shown here integrated with a ScImage cardiovascular information system (CVIS). Both companies displayed on the expo floor at ASNC 2019. The software creates a single page report seen here. PET perfusion imaging was a big topic at the conference.
Rupa Sanghani, M.D., FASNC, associate professor, Rush Medical College, director of nuclear cardiology and stress laboratory, Rush University Medical Center, and associate director, Rush Heart Center for Women, explains how to create a high-volume cardiac positron emission tomography (PET) imaging program. She spoke on this topic at the 2019 meeting of the American Society Nuclear Cardiology (ASNC) and led a tour with attendees of the PET-CT system at Rush, which was located close to the conference. #ASNC
With the advent and optimization of nuclear scintigraphy protocols using bone-avid radiotracers, cardiac amyloidosis caused by transthyretin protein (ATTR) can now be diagnosed noninvasively without a costly tissue biopsy. The radiotracer 99mTc-pyrophosphate (99mTc-PYP) binds to deposited ATTR amyloid fibrils in the myocardium and can be visualized using planar and SPECT imaging. This is Figure 2, showing how SPECT imaging allows the reader to distinguish between blood pool activity (ventricular cavity, etc) and myocardial activity and identify regional myocardial differences in radiotracer uptake.
A comparison of the first-ever image of a black hole released this week by the Event Horizon Telescope collaboration et al. and a cardiac nuclear imaging exam. Left is the black hole, and right is a similar nuclear imaging exam of the heart showing a similar ischemic perfusion defect to the black hole.