News | Stents | January 25, 2018

Elixir Unveils Transformational DynamX Stent Featuring Adaptive Segments that Uncage the Stented Artery

Elixir reveals new category of ‘Bioadaptive Drug Eluting Stents’ (BA- DES), sharing DynamX technology, preclinical data, and clinical program at 29th Transcatheter Cardiovascular Therapeutics Conference

 

Elixir Medical Corporation Unveils Transformational DynamX Stent Featuring Adaptive Segments that Uncage the Stented Artery

January 25, 2018 – Elixir Medical Corporation, a leader in the development of breakthrough adaptive remodeling technologies designed to mimic the normal arterial function after cardiovascular and peripheral vascular disease intervention, unveiled for the first time its novel stent technology, DynamXTM, a bioadaptive drug-eluting stent (BA-DES) platform at the Transcatheter Cardiovascular Therapeutics (TCT) conference in Denver.

DynamX, a 71 microns thin cobalt-chromium DES coated with a thin, biodegradable polymer coating that releases Novolimus, an anti-proliferative and anti-inflammatory, is the first of its kind in its ability to allow the vessel to resume arterial pulsatile motion and the Glagovian phenomenon of adaptive remodeling which are both essential for slowing disease progression and minimizing clinical events. Adaptive segments in the stent are held intact by the thin biodegradable polymer coating designed to absorb in six months allowing the adaptive segments to uncage the stent and restore the natural pulsatile motion and adaptive remodeling of the artery.

Current DES permanently cages the artery, causing geometric distortion and stresses that contribute to fractures in approximately 20 percent of stents implanted leading to clinical events. DynamX demonstrated significantly improved conformability, and reduced torsional and longitudinal stresses compared to current DES, thereby reducing geometric distortion of arteries and the potential for stent fractures and clinical events.

“The acute performance of DynamX matched the best in class DES,” said Professor Stefan Verheye, M.D., Ph.D., Antwerp, Belgium.

“I am very excited about the potential of DynamX leading PCI to the next frontier,” said Verheye.

Verheye presented DynamX’s clinical program overview at the TCT conference and was joined by a distinguished panel of faculty Co-Chairs: Martin Leon, Dean Kereiakes and Roxana Mehran.

In addition to launching a new genre of bioadaptive drug-eluting stents with DynamX, Elixir also continues to make advances with its bioresorbable scaffold programs, DESolve CX and DESolve NXT. DESolve’s ability to degrade in six months and nearly completely resorb in one year, while demonstrating positive adaptive remodeling at six-month follow-up have all been affirmations of their respective proprietary technologies and the promising future of the category.

“Elixir is committed to lead the industry to a new and exciting era with its bio-adaptive DynamX DES,” said Motasim Sirhan, CEO of Elixir Medical Corporation. “Elixir is executing on a two-pronged strategy with BRS and BA-DES to develop innovative, adaptive remodeling technologies designed to restore the normal function of arteries.”

For more information: www.elixirmedical.com

Related Content

TCT cancels in-person meeting and goes virtual due to COVID-19
News | Cath Lab | May 27, 2020
May 27, 2020 — To ensure the health and safety of all attendees due to the ongoing COVID-19 (SARS-CoV-2) pandemic, th
Patients undergoing cardiac catheterization are traditionally instructed to follow nothing by mouth, or nil per os (NPO), as there are no current standardized fasting protocols, but the CHOWNOW study found patients do not need to fast and will have similar outcomes. #SCAI2020
Feature | Cath Lab | May 18, 2020
May 18, 2020 – Patients undergoing cardiac catheterization are traditionally instructed to follow nothing by mouth, o
htisham Mahmud, M.D., FSCAI, president of the Society for Cardiovascular Angiography and Interventions (SCAI) and chief, Division of Cardiovascular Medicine at UC San Diego Medical Center,
Podcast | Cath Lab | May 13, 2020
This podcast is an interview with Ehtisham Mahmud, M.D., FSCAI, president of the Society for Cardiovascular Angiograp
Nuance Communications Inc. introduced Nuance Cardiovascular CAPD, a new computer-assisted physician documentation (CAPD) solution designed to help cardiologists improve the quality of complex documentation and the accuracy of reimbursement for cardiac catheterization procedures. The Nuance Cardiovascular CAPD solution is available through a partnership with ZHealth for this solution, which is based on patented algorithms built with ZHealth’s interventional documentation and coding expertise.
News | Cath Lab | January 31, 2020
January 29, 2020 – Nuance Communications Inc.
Videos | Cath Lab | January 09, 2020
Haval Chweich, M.D., medical director of the cardiac critical care unit (CCU) at Tufts Medical Center, and assistant...
People watch the live presentation of the five-year EXCEL Trial data by Gregg Stone, M.D., in the Abbott booth at TCT 2019. Abbott makes the Xience stent used in the trial, which compared equally with long-term CABG surgical outcomes.  In early December 2019, leaders of the European Association for Cardiothoracic Surgery (EACTS) withdrew their support for European practice guidelines that endorse the use of coronary stents in many patients with left main coronary artery disease.

People watch the live presentation of the five-year EXCEL Trial data by Gregg Stone, M.D., in the Abbott booth at TCT 2019. Abbott makes the Xience stent used in the trial, which compared equally with long-term CABG surgical outcomes.

News | Cath Lab | January 02, 2020 | Dave Fornell, Editor
January 2, 2020 — In early December 2019, leaders of the European As...