Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

Echocardiography strain imaging at ASE. #ASE2020
News | ASE | August 20, 2020
August 20, 2020 – More than 350 posters featuring cutting edge research on the advances in cardiovascular ultrasound...
The World Alliance of Societies of Echocardiography (WASE) Normal Values Study is a cross-sectional study designed to obtain universal global reference ranges for both 2-D and 3-D echocardiographic (2DE, 3DE) data to identify geographical differences in echocardiographic measurements. Launched in 2016, the WASE study prospectively enrolled healthy individuals free from cardiac, lung, and kidney disease from 19 centers in 15 countries. #ASE #ASE2020
News | Cardiovascular Ultrasound | August 20, 2020
August 20, 2020 – The World Alliance of Societies of Echocardiography (WASE) Normal Values Study is a cross-sectional...
Photo of Eyes Predicts Death and Readmission in Heart Failure Patients. Getty Images.

Photo of Eyes Predicts Death and Readmission in Heart Failure Patients. Getty Images.

News | Heart Failure | August 17, 2020
  August 17, 2020 — Pupil size predicts death and hospital readmission in patients with heart failure, according to...
Videos | CT Angiography (CTA) | August 11, 2020
Todd Villines, M.D., FACC, FAHA, MSCCT, explains some of most influential cardiac CT clinical papers from the past year...
The TactiFlex PAF investigational device exemption (IDE) study will evaluate he investigational TactiFlex Ablation Catheter, Sensor Enabled (SE) to treat people suffering from paroxysmal atrial fibrillation (PAF). 

The TactiFlex PAF investigational device exemption (IDE) study will evaluate he investigational TactiFlex Ablation Catheter, Sensor Enabled (SE) to treat people suffering from paroxysmal atrial fibrillation (PAF). 

News | Atrial Fibrillation | August 04, 2020
August 4, 2020 — Abbott announced the first enrollments in the TactiFlex PAF  investigational device exemption (IDE)...
Examples of  allogeneic cardiac cells (also called cardiosphere-derived cells or CDCs).

Examples of allogeneic cardiac cells (also called cardiosphere-derived cells or CDCs), that were used to treat heart attack infarcts to reverse heart failure in the ALLSTAR trial.

News | Heart Failure | August 04, 2020
August 4, 2020 - More than three years after a clinical trial was prematurely ended for failing to show progress in...
Large Study in Japan Finds High Survival Rates With Impella Heart Pump
News | Cardiogenic Shock | August 03, 2020
August 3, 2020 — A three-year, investigator-led, prospective study of Japanese patients who received an Impella heart...
Dapagliflozin (Farxiga) heart failure drug performs very will to improve outcomes for patients with chronic kidney disease.
News | Pharmaceuticals | July 28, 2020
July 28, 2020 — AstraZeneca's heart failure medication dapagliflozin (Farxiga) significantly reduced the worsening of...
News | Stents | July 24, 2020
July 24, 2020 — CeloNova BioSciences Inc. announced it successfully completed enrollment of the COBRA REDUCE randomized...
Figure B — Top panel, neutrophils noted in collections within small vessels (blue arrow), plump endothelial cells (yellow arrowhead) and a single perivascular dying myocyte (blue arrowhead). Bottom panel, single myocyte undergoing degeneration (blue arrowhead) and plump endothelial cell (yellow arrowhead). Figure C — Electron microscopy, showing particles of SARS-CoV-2 virus present within a cardiac endothelial cell (blue arrowheads), but not present in neighboring cardiac myocyte. #COVID19

Figure B — Top panel, neutrophils noted in collections within small vessels (blue arrow), plump endothelial cells (yellow arrowhead) and a single perivascular dying myocyte (blue arrowhead). Bottom panel, single myocyte undergoing degeneration (blue arrowhead) and plump endothelial cell (yellow arrowhead). Figure C — Electron microscopy, showing particles of SARS-CoV-2 virus present within a cardiac endothelial cell (blue arrowheads), but not present in neighboring cardiac myocyte (left side of image). Images from Circulation.

Feature | Coronavirus (COVID-19) | July 23, 2020
July 23, 2020 - A series of autopsies conducted by Louisiana State University (LSU) Health New Orleans pathologists...
Hershey's Chocolate display with samples and coco pods at the American College of Cardiology (ACC) 2012 annual meeting. The company was making the case that chocolate can be good for your heart, which is now supported by several studies. Photo by Dave Fornell

Hershey's Chocolate display with samples and coco pods at the American College of Cardiology (ACC) 2012 annual meeting. The company was making the case that chocolate can be good for your heart, which is now supported by several studies. Photo by Dave Fornell

News | Cardiovascular Clinical Studies | July 22, 2020
July 22, 2020 — Eating chocolate at least once a week is linked with a reduced risk of heart disease, according to...
The European Society of Cardiology (ESC) will host several Hot Lines sessions that will include some of the latest clinical science presentations in cardiology at the 2020 annual congress digital meeting. The meeting has gone virtual due to the ongoing pandemic. 
News | ESC | July 21, 2020
The European Society of Cardiology (ESC) will host several Hot Lines sessions that will include some of the latest...
Videos | Cardiogenic Shock | July 15, 2020
Navin Kapur, M.D., FAHA, FACC, FSCAI, director, Acute Mechanical Circulatory Support Program and executive director of...
Cardiac MRI for four children with clinical diagnosis of acute myocarditis in the setting of COVID-19–related Kawasaki-like symptoms of Multisystem Inflammatory Syndrome in Children (MIS-C). Cardiac MRI of COVID pediatric COVID-19 patients.

Cardiac MRI for four children with clinical diagnosis of acute myocarditis in the setting of COVID-19–related Kawasaki-like symptoms of MIS-C. The top panel demonstrates minimal pericardial effusion on cine images. The second panel demonstrates increased T2-STIR signal intensity with average ratios between myocardium and muscle > 2 in patient 2 (12-year-old male), patient 3 (11-year-old female) and patient 4 (6-year-old female). The third panel demonstrates abnormal native-T1 mapping, which was > 1,100 ms in patients 2, 3 and 4 and normal in patient 1 (8-year-old female). The bottom panel demonstrates absence of late gadolinium enhancement (LGE) in patients 2 and 3. Myocardial null times were recognized as too short in patient 4 but could not be repeated due to lack of further patient cooperation; however review of Look Locker images and additional sequences revealed no LGE. Image courtesy of RSNA.

Feature | Coronavirus (COVID-19) | July 09, 2020
July 8, 2020 — Cardiac magnetic resonance imaging (MRI) has been shown to be helpful in evaluating multisystem...
Older Critically Ill COVID-19 Patients May Have Increased Risk of Bradycardia With Lopinavir and Ritonavir.

Photo copyright American Heart Association, used with permission.

Feature | Coronavirus (COVID-19) | July 09, 2020
July 9, 2020 — Older, critically ill patients with COVID-19 (SARS-CoV-2) who received a combination of the...