Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

First dedicated registry to investigate DCB performance in isolated popliteal artery lesions shows Passeo-18 Lux DCB as beneficial treatment for challenging anatomical segment

News | Drug-Eluting Balloons

BIOLUX P-III BENELUX All-Comers Registry Demonstrates Safety and Efficacy of BIOTRONIK’s Drug-Coated Balloon in Isolated Popliteal Lesions at 24 Months

September 14, 2023 — BIOTRONIK announced the two-year-results from the BIOLUX P-III BENELUX all-comers registry ...

September 14, 2023

Reduced inflammation at the site of myocardial infarction and improved heart function demonstrated. Novel therapy to modulate immune response with apoptotic cell-derived nanovesicles

News | Cardiovascular Clinical Studies

Myocardial Infarction, the Number One Cause of Sudden Death, May be Treated by Modulating the Immune Response

September 14, 2023 — Myocardial infarction, the number one cause of sudden death in adults and the number two cause of ...

September 14, 2023

Mineralys Therapeutics, Inc. has presented final results from the Target-HTN Phase 2 trial of lorundrostat, a highly selective aldosterone synthase inhibitor, in individuals with uncontrolled hypertension (uHTN) and resistant hypertension (rHTN).

News | Cardiovascular Clinical Studies

Mineralys Therapeutics Presents Target-HTN Phase 2 Trial Results at 2023 AHA Hypertension Scientific Sessions

September 12, 2023 — Mineralys Therapeutics, Inc. has presented final results from the Target-HTN Phase 2 trial of ...

September 12, 2023

Interim results from SOTERIA open-label extension study represent longest safety and efficacy analysis of sotatercept to date

News | Cardiovascular Clinical Studies

Merck Presents New Analyses Supporting the Promising Potential of Sotatercept, its Investigational Medicine for Adults with Pulmonary Arterial Hypertension (PAH)

September 12, 2023 — Merck announced new analyses from studies of sotatercept, Merck’s novel investigational activin ...

September 12, 2023

The first patient has been enrolled in a UK study of large vessel de novo coronary artery disease treated with SELUTION SLR

News | Drug-Eluting Balloons

MedAlliance Announces Enrollment of First Patient in SELUTION SLR LOVE-DEB Coronary Study

September 11, 2023 — The first patient has been enrolled in a UK study of large vessel de novo coronary artery disease t ...

September 11, 2023

Videos | Pharmaceuticals

VIDEO, Part 2: Hypertrophic Cardiomyopathy in Focus

In Part 2 of DAIC’s 3-part “One on One” series with Dr. Christine Seidman, a discussion on the discovery of gene-based ...

September 11, 2023

the Company is exploring development of a new Phase III clinical trial protocol

News | Heart Failure

BioCardia Announces Clarification and Next Steps on its Autologous CardiAMP Cell Therapy Programs

September 8, 2023 — BioCardia, Inc., a developer of cellular and cell-derived therapeutics for the treatment of ...

September 08, 2023

MPROVE-ISCHEMIA, a randomized, placebo-controlled trial, with topline data expected in 4Q 2023

News | Cardiovascular Clinical Studies

Imbria Pharmaceuticals Completes Enrollment in the Phase 2 IMPROVE-ISCHEMIA Clinical Trial of Ninerafaxstat in Patients with Stable Angina

September 8, 2023 — Imbria Pharmaceuticals, Inc., a clinical stage, cardiometabolic company dedicated to developing ...

September 08, 2023

Patients of African ancestry with dilated cardiomyopathy (DCM) are less likely to have clinically actionable variants in DCM genes than those of European ancestry

News | Cardiovascular Clinical Studies

Study Highlights Need for Diversity in Clinical Trials to Better Understand, Treat Inherited Heart Muscle Disease

September 8, 2023 — Patients of African ancestry with dilated cardiomyopathy (DCM) are less likely to have clinically ...

September 08, 2023

Annual Scientific Symposium will take place October 23-26 in San Francisco

Feature | TCT

CRF Announces TCT 2023 Late-breaking Clinical Trials

September 6, 2023 — The Cardiovascular Research Foundation (CRF) has announced the TCT 2023 late-breaking clinical ...

September 06, 2023

Magenta Medical, developer of the Elevate heart pump system, an FDA Designated Breakthrough Device, recently announced the completion of its FDA-approved Early Feasibility Study for the high-risk percutaneous coronary intervention (HR-PCI) indication.

News | Cardiovascular Clinical Studies

Magenta Medical Completes Enrollment to Early Feasibility Study for World’s Smallest Heart Pump

September 6, 2023 — Magenta Medical, developer of the Elevate heart pump system, an FDA Designated Breakthrough Device ...

September 06, 2023

Results from Two Phase 3 studies evaluating CAMZYOS (mavacamten) for symptomatic obstructive hypertrophic cardiomyopathy (HCM) were recently released by Bristol Myers Squibb.

News | Cardiovascular Clinical Studies

Results from Two Phase 3 Studies Evaluating Mavacamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy Released

September 5, 2023 — New long-term follow-up results from two Phase 3 studies evaluating CAMZYOS (mavacamten), a first-in ...

September 05, 2023

The Ohio State University Wexner Medical Center randomized the first patient in the world in a clinical trial evaluating the effectiveness of a device designed to alleviate heart failure symptoms.

News | Cardiovascular Clinical Studies

Ohio State First in World to Participate in Trial of Device Designed to Alleviate Heart Failure Symptoms

September 5, 2023 — The Ohio State University Wexner Medical Center randomized the first patient in the world in a ...

September 05, 2023

News | Heart Failure

Redo Transcatheter Aortic Valve Replacement Proven Effective, Safe

September 5, 2023 — Cedars-Sinai investigators are leaders in the innovation and use of transcatheter aortic valve ...

September 05, 2023

First-in-Human Study Also Showed the Return of Vasomotion in Patients Treated with the DREAMS 3G Scaffold

News | Stents Bioresorbable

BIOMAG-I Study OCT Analysis Confirmed That BIOTRONIK’s Newest Resorbable Magnesium Scaffold Resorbed at 12 Months

September 5, 2023 — New data from the BIOMAG-I first-in-human trial shed light on the vascular healing process following ...

September 05, 2023