Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

MPROVE-ISCHEMIA, a randomized, placebo-controlled trial, with topline data expected in 4Q 2023

News | Cardiovascular Clinical Studies

Imbria Pharmaceuticals Completes Enrollment in the Phase 2 IMPROVE-ISCHEMIA Clinical Trial of Ninerafaxstat in Patients with Stable Angina

September 8, 2023 — Imbria Pharmaceuticals, Inc., a clinical stage, cardiometabolic company dedicated to developing ...

September 08, 2023

Patients of African ancestry with dilated cardiomyopathy (DCM) are less likely to have clinically actionable variants in DCM genes than those of European ancestry

News | Cardiovascular Clinical Studies

Study Highlights Need for Diversity in Clinical Trials to Better Understand, Treat Inherited Heart Muscle Disease

September 8, 2023 — Patients of African ancestry with dilated cardiomyopathy (DCM) are less likely to have clinically ...

September 08, 2023

Annual Scientific Symposium will take place October 23-26 in San Francisco

Feature | TCT

CRF Announces TCT 2023 Late-breaking Clinical Trials

September 6, 2023 — The Cardiovascular Research Foundation (CRF) has announced the TCT 2023 late-breaking clinical ...

September 06, 2023

Magenta Medical, developer of the Elevate heart pump system, an FDA Designated Breakthrough Device, recently announced the completion of its FDA-approved Early Feasibility Study for the high-risk percutaneous coronary intervention (HR-PCI) indication.

News | Cardiovascular Clinical Studies

Magenta Medical Completes Enrollment to Early Feasibility Study for World’s Smallest Heart Pump

September 6, 2023 — Magenta Medical, developer of the Elevate heart pump system, an FDA Designated Breakthrough Device ...

September 06, 2023

Results from Two Phase 3 studies evaluating CAMZYOS (mavacamten) for symptomatic obstructive hypertrophic cardiomyopathy (HCM) were recently released by Bristol Myers Squibb.

News | Cardiovascular Clinical Studies

Results from Two Phase 3 Studies Evaluating Mavacamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy Released

September 5, 2023 — New long-term follow-up results from two Phase 3 studies evaluating CAMZYOS (mavacamten), a first-in ...

September 05, 2023

The Ohio State University Wexner Medical Center randomized the first patient in the world in a clinical trial evaluating the effectiveness of a device designed to alleviate heart failure symptoms.

News | Cardiovascular Clinical Studies

Ohio State First in World to Participate in Trial of Device Designed to Alleviate Heart Failure Symptoms

September 5, 2023 — The Ohio State University Wexner Medical Center randomized the first patient in the world in a ...

September 05, 2023

News | Heart Failure

Redo Transcatheter Aortic Valve Replacement Proven Effective, Safe

September 5, 2023 — Cedars-Sinai investigators are leaders in the innovation and use of transcatheter aortic valve ...

September 05, 2023

First-in-Human Study Also Showed the Return of Vasomotion in Patients Treated with the DREAMS 3G Scaffold

News | Stents Bioresorbable

BIOMAG-I Study OCT Analysis Confirmed That BIOTRONIK’s Newest Resorbable Magnesium Scaffold Resorbed at 12 Months

September 5, 2023 — New data from the BIOMAG-I first-in-human trial shed light on the vascular healing process following ...

September 05, 2023

CASTLE-HTx trial presented in a Hot Line session at ESC Congress 2023

News | Atrial Fibrillation

Atrial Fibrillation Ablation Improves Outcomes in Patients with End-stage Heart Failure

August 31, 2023 — Atrial fibrillation ablation is associated with lower rates of death, urgent heart transplantation or ...

August 31, 2023

ECLS-SHOCK trial presented in a Hot Line session at ESC Congress 2023

News | Cardiovascular Clinical Studies

ECLS-SHOCK Trial Reports Mortality Data for Extracorporeal Life Support

August 31, 2023 — Early extracorporeal life support (ECLS) does not improve survival in patients with acute myocardial ...

August 31, 2023

Non-inferiority and safety of one-month DAPT with BIOTRONIK’s drug-eluting stent presented as late-breaker at ESC 2023

News | Cardiovascular Clinical Studies

12-Month-Data of BIOFLOW-DAPT Study Show Positive Results for Orsiro Mission DES With Short DAPT

August 30, 2023 — BIOFLOW-DAPT one-year-data demonstrated non-inferiority and a good safety profile for the Orsiro ...

August 30, 2023

MULTISTARS AMI trial presented in a Hot Line session today at ESC Congress 2023

News | Cardiovascular Clinical Studies

Trial Investigates Timing of Complete Revascularization for Myocardial Infarction

August 30, 2023 — Immediate multivessel percutaneous coronary intervention (PCI) is non-inferior to staged multivessel ...

August 30, 2023

Optical coherence tomography (OCT) is non-inferior to intravascular ultrasound (IVUS) for guiding percutaneous coronary intervention (PCI), according to late breaking research presented in a Hot Line session at ESC Congress 2023

News | Optical Coherence Tomography (OCT)

Optical Coherence Tomography Non-inferior to Intravascular Ultrasound for Stent Guidance

August 29, 2023 — Optical coherence tomography (OCT) is non-inferior to intravascular ultrasound (IVUS) for guiding ...

August 29, 2023

The European Society of Cardiology (ESC) Guidelines on acute coronary syndromes are published online today in European Heart Journal.

News | Heart Failure

First ESC Guidelines Covering All Acute Coronary Syndromes Published

August 29, 2023 — The European Society of Cardiology (ESC) Guidelines on acute coronary syndromes are published online ...

August 29, 2023

Data from the landmark ILUMIEN IV trial, the first randomized imaging trial with global representation, has the potential to change clinical practice related to stent placement

News | Optical Coherence Tomography (OCT)

Abbott Unveils Late-breaking Data Showing Intravascular Imaging Via OCT can Improve Stent Procedural Outcomes, Especially in Complex Cases

August 29, 2023 — Abbott announced late-breaking data from the first-of-its-kind ILUMIEN IV OPTIMAL PCI (ILUMIEN IV) ...

August 29, 2023