Optical Coherence Tomography (OCT)

Optical coherence tomography (OCT) is an catheter-based intravascular imaging technology that uses low-coherence light interferometry, using near-infrared light, to capture high-resolution 2-D and 3-D image reconstructions of coronary arteries. It has a lower level of tissue penetration than intravascular ultrasound (IVUS), but offers much higher resolution images of the tissues. It is used to determine the nature and extent of the atheroscleratic disease in the vessel wall, to assess in-stent restenosis and aid catheter procedure navigation in the cath lab.

SpectraWave is developing a a new intravascular imaging system that combines two currently available modalities. This likely includes optical coherence tomography (OCT), left, which can define structures within the vessel and vessel wall.  Near infrared spectroscopy (NIRS), right, enables a spectral chemical analysis of the vessel walls to show areas of high lipid content, and specifically can identify lipid-core plaques that are associated with heart attack-causing plaque ruptures.

News | Cath Lab | February 16, 2021
February 16, 2021 – SpectraWave Inc. announced a $13.2 million series A-2 financing to support completion of product...
Women’s Heart Attack Research Program (HARP) shows combining OCT and cardiac MRI can detect the underlying cause of heart attack in women who did not have blocked arteries

The Women’s Heart Attack Research Program (HARP) study shows combining OCT and cardiac MRI can help detect the underlying cause of heart attacks in women who did not have blocked arteries.

News | Cardiac Imaging | November 17, 2020
November 17, 2020 — Diagnostic imaging techniques were able to find the underlying cause of heart attack in many women...
Angiography with a co-registered view of pressure drops according iFR readings in a coronary vessel. The DEFINE PCI study showed patients had improved outcomes and less recurrent chest pain at one year using iFR physiologic measurements combined with landmarks shown on angiographic imaging to better guide therapy. Image by Philips Healthcare. #TCT #TCT2020 #TCTconnect

Angiography with a co-registered view of pressure drops according iFR readings in a coronary vessel. The DEFINE PCI study showed patients had improved outcomes and less recurrent chest pain at one year using iFR physiologic measurements combined with landmarks shown on angiographic imaging to better guide therapy. Image by Philips Healthcare

Feature | FFR Technologies | October 30, 2020 | Dave Fornell, Editor
Fractional flow reserve (FFR) is considered the gold standard measure whether a coronary lesions needs a percutaneous...
A longitudinal vessel assessment may demonstrate co-existence of multiple plaque morphologies on OCT, including superficial calcification with thrombus, healed plaque, plaque rupture, lipidic plaque with a thin capped fibrous atheroma (TCFA). #TCTconnect #TCT2020

A longitudinal vessel assessment may demonstrate co-existence of multiple plaque morphologies on OCT, including superficial calcification with thrombus, healed plaque, plaque rupture, lipidic plaque with a thin cap fibro-atheroma (TCFA).

News | Cath Lab | October 18, 2020
October 18, 2020 – Data from the COMBINE (OCT-FFR) study found that the use of FFR combined with OCT imaging can help...
The researchers developed an ultra thin monolithic OCT endoscope that overcomes the limitations of current, larger OCT catheters by using 3-D printed components.

The researchers developed an ultra thin monolithic OCT endoscope that overcomes the limitations of current, larger OCT catheters by using 3-D printed components.

News | Optical Coherence Tomography (OCT) | October 01, 2020
October 1, 2020 — A team of researchers led by the University of Adelaide and University of Stuttgart has used 3-D...
Explanation of optical coherence imaging (OCT) coronary imaging.
Feature | Optical Coherence Tomography (OCT) | September 17, 2020 | Aziz Maksoud M.D., FACC, FSCAI, and Bassem Chehab, M.D., FACC, FSCAI
Although not a new technology, optical coherence tomography (OCT) is the dark horse of imaging that could give...
News | Chronic Total Occlusion (CTO) | September 14, 2020
September 14, 2020 — Avinger received U.S. Food and Drug Administration (FDA) 510(k) clearance from the FDA for its...
Videos | Cardiovascular Business | September 14, 2020
Nick West, M.D., chief medical officer for Abbott, explains the details from a survey of 1,400 patients, physicians and...
Abbott OCT intravascular imaging explained.
News | Optical Coherence Tomography (OCT) | June 26, 2020
June 26, 2020 — Abbott announced new data from the company's LightLab Initiative that showed optical coherence...
An OCT intracoronary image showing instent restenosis. The white spots in the vessel wall casting shadows are the stent struts. OCT image data might be used in the future to assess FFR to determine the severity of lesions and determine if they need to be stented.

An OCT intracoronary image showing instent restenosis. The white spots in the vessel wall casting shadows are the stent struts. OCT image data might be used in the future to assess FFR to determine the severity of lesions and determine if they need to be stented.

News | FFR Technologies | May 15, 2020
May 15, 2020 – A late-breaking study aimed to evaluate whether optical coherence tomography (OCT) can predict...
A complex PCI case to revascularize a chronic total occlusion (CTO) at Henry Ford Hospital in Detroit. Complex PCI and CHIP cases are increasing patient volumes in the cath lab and using a minimally invasive approach in patients who otherwise would have been sent for CABG. Pictured is Khaldoon Alaswad, M.D. DAIC staff photo by Dave Fornell

A complex PCI case to revascularize a chronic total occlusion (CTO) at Henry Ford Hospital in Detroit. Complex PCI and CHIP cases are increasing patient volumes in the cath lab and using a minimally invasive approach in patients who otherwise would have been sent for CABG. Pictured is Khaldoon Alaswad, M.D. (right) who is proctoring a fellow in treating CTOs.

Feature | Cath Lab | September 13, 2018 | Artur Kim, Kamran Zamanian
Coronary artery disease (CAD) is a multifaceted disease that demands various approaches in terms of diagnosis and...
First U.S. Patients Treated With Second-Generation Pantheris Atherectomy Device
News | Atherectomy Devices | July 18, 2018
July 18, 2018 — Avinger Inc. announced in June that several physicians have successfully treated over 40 patients for...
OCT Reveals Excellent Healing Profile for Complex CAD Patients With Resolute Onyx DES
News | Stents Drug Eluting | May 29, 2018
May 29, 2018 – Investigators recently unveiled clinical data from the independently run Onyx 1-Month OCT Study showing...
Avinger Receives FDA Clearance of Next-Generation Pantheris Device
Technology | Atherectomy Devices | May 24, 2018
May 24, 2018 — Avinger Inc. announced that the company received 510(k) clearance from the U.S. Food & Drug...
Recent Acquisitions Eroding Prices in Billion Dollar European Interventional Cardiology cath lab Market.
Feature | Cath Lab | May 07, 2018 | Simon Trinh and Jeffrey Wong
The European interventional cardiology market is currently valued at nearly $1.4 billion. This is a mature market that...