News | EP Mapping and Imaging Systems | October 15, 2019

Kardium Announces Successful Results From GLOBAL-AF Study

Patients treated with Globe electrophysiology mapping and ablation solution showed 76 percent freedom from atrial fibrillation at 12 months after single treatment

Kardium Announces Successful Results From GLOBAL-AF Study

October 15, 2019 — Kardium Inc. announced that the Globe mapping and ablation system has successfully demonstrated safety and efficacy in the GLOBAL-AF study. The results of the study were published in the Journal of Cardiovascular Electrophysiology.[1] The study demonstrated a 76 percent percent freedom from atrial fibrillation at 12 months after a single treatment with the Globe system.

“I am very excited about the results from this first clinical experience with the Globe system” said Prof. Hans Kottkamp, head of electrophysiology, Sana Hospitals, Düsseldorf, Germany, the principal investigator. “The Globe system has demonstrated the ability to provide rapid and effective pulmonary vein isolation. In addition, the ability to perform high-resolution mapping and ablation of the atrium will deliver a unique and comprehensive treatment for patients that has the potential to further improve outcomes and advance new strategies for the treatment of AF.”

The Globe system is a mapping and ablation solution that consists of a catheter with 122 electrodes and advanced software, that together enable rapid pulmonary vein isolation, high-resolution mapping and the ability to ablate anywhere in the atrium, all with a single catheter.

Atrial fibrillation is the most common heart rhythm disorder and affects about 33 million people worldwide. It can increase the risk of stroke by up to five times.

The GLOBAL-AF study is a prospective multicenter study that evaluated the safety and effectiveness of the system in 60 patients at two centers in Europe. Patients were assessed for atrial fibrillation with seven-day continuous Holter monitoring at discharge and then 3, 6 and 12 months after the treatment. Patients in the efficacy cohort had 100 percent pulmonary vein isolation and 76 percent freedom from atrial fibrillation at 12 months, off antiarrhythmic drugs, after a single procedure.

For more information: www.kardium.com

Reference

1. Kottkamp H., Hindricks G., Ponisch C., et al. Global multielectrode contact‐mapping plus ablation with a single catheter in patients with atrial fibrillation: Global AF study. Journal of Cardiovascular Electrophysiology, published online Sept. 11, 2019. https://doi.org/10.1111/jce.14172


Related Content

News | Atrial Fibrillation

September 14, 2022 — In recognition of Atrial Fibrillation (AFib) Awareness Month, Biosense Webster, Inc., part of ...

Home September 14, 2022
Home
News | Atrial Fibrillation

September 9, 2 022 — A large-scale international study led by Mount Sinai has yielded the first risk score that can help ...

Home September 09, 2022
Home
News | Atrial Fibrillation

August 31, 2022 — Science has long shown that men are at greater risk for developing atrial fibrillation (AFib) than ...

Home August 31, 2022
Home
News | Atrial Fibrillation

July 29, 2022 — A cohort study of persons with incident atrial fibrillation (AF) has found that AF after noncardiac ...

Home July 29, 2022
Home
News | Atrial Fibrillation

July 20, 2022 — CardioFocus, Inc., a medical device company dedicated to advancing ablation treatments for atrial ...

Home July 20, 2022
Home
News | Atrial Fibrillation

July 6, 2022 — Atrial fibrillation (AF) is a prevalent cardiovascular condition with one of the highest rates of ...

Home July 06, 2022
Home
News | Atrial Fibrillation

June 30, 2022 — A new onset of a rapid or irregular heartbeat that develops after surgery, often within a few days, is ...

Home June 30, 2022
Home
News | Atrial Fibrillation

May 17, 2022 — Results of a new study reveal Black patients hospitalized with atrial fibrillation (AF) are under ...

Home May 17, 2022
Home
News | Atrial Fibrillation

May 17, 2022 — Results from a new study show success of intended same day discharge (SDD) improves over time for ...

Home May 17, 2022
Home
News | Atrial Fibrillation

May 17, 2022 — On the heels of its landmark valvular heart disease (VHD) prevalence abstract published in Journal of the ...

Home May 17, 2022
Home
Subscribe Now