Dapagliflozin did not significantly reduce organ failure or death in high-risk hospitalized COVID-19 patients in the DARE-19 trial results, presented at ACC.21. #ACC #ACC21 #ACC2021
May 18, 2021
Dapagliflozin Did Not Significantly Reduce Organ Failure or Death in High-Risk Hospitalized COVID-19 Patients
May 18, 2021 — Dapagliflozin (Farxiga), a sodium-glucose co-transporter 2 (SGLT2) inhibitor, did not significantly…
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This trial used a therapeutic hypothermia system that used balloon catheters filled with cooled saline, such as the Zoll Thermogard XP temperature management system. #ACC21 #ACC2021 #therapeutichypothermia
May 17, 2021
Lower Temperature Therapeutic Hypothermia Did Not Improve Outcomes After Cardiac Arrest
May 17, 2021 — In patients receiving therapeutic hypothermia after suffering out-of-hospital cardiac arrest, those who…
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The anticoagulant rivaroxaban (Xarelto), in addition to low-dose aspirin, significantly reduced the occurrence of total severe events of the heart, limb or brain and issues related to other vascular complications in patients with symptomatic peripheral artery disease (PAD) who underwent lower extremity revascularization. The findings from the VOYAGER PAD trial were presented at the American College of Cardiology (ACC) 2021 Scientific Session.
May 17, 2021
Rivaroxaban Reduces First and Total Ischemic Events in Patients with Peripheral Artery Disease
May 17, 2021 — The anticoagulant rivaroxaban (Xarelto), in addition to low-dose aspirin, significantly reduced the…
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The FLOWER-MI trial presented at ACC 2021 found no benefit to FFR-guided PCI in STEMI with multi-vessel disease. #ACC21 #ACC2021 #FFR
May 17, 2021
No Benefit to FFR-guided PCI in STEMI Patients With Multi-Vessel Disease
May 17, 2021 — In patients who received a coronary stent for an ST-elevation myocardial infarction (STEMI) heart attack…
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DAIC magazine won Overall Excellence Finalist/Multi-platform Package of the Year for its coverage of the COVID-19 Pandemic’s Toll on Cardiology, National. The entry won an honor mention for its coverage of the COVID pandemic. Dave Fornell is the editor of DAIC.
By Melinda Taschetta-Millane
May 17, 2021
DAIC Brings Home National, Regional Honors
Diagnostic and Interventional Cardiology (DAIC) and its sister publication Imaging Technology News (ITN) recently took…
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The Record Paradise RDN catheter uses a balloon catheter filled with water to cool the vessel wall as ultrasound-based ablation energy is delivered. It delivers a ring of ablative energy to a depth of 1-6 mm. Kirtane said it requires 2-3 sonications lasting 7 seconds each in each of the main renal arteries. #ACC21 #ACC2021 #RDN
By Dave Fornell, Editor
May 16, 2021
Renal Denervation Lowers Blood Pressure in Medication-Resistant Hypertension 
May 16, 2021 — Two months after undergoing renal denervation (RDN) with the ReCor Paradise renal denervation system,…
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Etripamil nasal spray was shown in a post-hoc analysis to resolve paroxysmal supraventricular tachycardia faster and more completely than placebo in most patients and reduced the number of emergency room visits for additional interventions. 
By Dave Fornell, Editor
May 16, 2021
Etripamil Nasal Spray Reduced ER Vistsis and More PSVT Resolution in New NODE-301 Analysis
May 16, 2020 — New data from in the NODE-301 Trial for the patient-administered nasal spray etripamil to resolve …
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The Boston Scientific Watchman device have performed better than expected in real-world patients outside of trials since it was introduced in 2015, according to data from the NCDR LAAO Registry. #ACC21 #ACC2021 #LAA #Watchman
May 16, 2021
NCDR LAAO Registry Shows Left Atrial Appendage Occlusion Associated With Low Rate of Stroke
May 15, 2021 - Transcatheter left atrial appendage occlusion (LAAO) with a Boston Scientific Watchman device was…
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The mechanism of action for mavacamten, a cardiac myosin inhibitor to treat obstructive hypertrophic cardiomyopathy (oHCM). EXPLORER-HCM trial #ACC21 #ACC2021
May 15, 2021
Mavacamten Is Effective in Treating Obstructive Hypertrophic Cardiomyopathy
May 15, 2021 — A new analysis of the Phase 3 EXPLORER-HCM study evaluating mavacamten, an investigational, first-in-…
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The combination heart failure drug sacubitril/valsartan did not significantly reduce the rate of heart failure or cardiovascular death following a heart attack compared to ramipril, an angiotensin converting enzyme (ACE) inhibitor. #ACC21 #ACC2021
May 15, 2021
Sacubitril/Valsartan Does Not Outperform ACE Inhibitor in Preventing Heart Failure After Heart Attack
May 15, 2021 — The combination heart failure drug sacubitril/valsartan (Entresto) did not significantly reduce the rate…
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In the LAAOS III trial, surgeons could seal off the LAA during the open heart procedure using sutures, staples or approved closure devices. The image shows a SentraHeart lasso type LAA occluder about to seal off the LAA from the outside of the heart. #ACC21 #ACC2021
May 15, 2021
Left Atrial Appendage Occlusion Reduces Stroke After Heart Surgery
May 15, 2021 — Patients with an elevated risk of stroke due to heart rhythm problems, or atrial fibrillation (AFib),…
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The ADAPTABLE trial found no significant differences in cardiovascular events or major bleeding in patients with pre-existing cardiovascular disease who were taking 81 milligrams (mg) baby aspirin, versus 325 mg of daily aspirin. Getty Images #ACC #ACC21 #ACC2021
May 15, 2021
Baby and Regular Strength Aspirin Equal in Cardiac Platelet Inhibition and Safety
May 15, 2021 — The ADAPTABLE trial found no significant differences in cardiovascular events or major bleeding in…
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An Edward Lifesciences Sapien TAVR valve during an implant procedure on angiography. There are still questions on how to best anticoagulate TAVR patients and the ATLANTIS study found Eloquis is not a good solution.
May 15, 2021
TAVR Anticoagulation With Apixaban Not Superior to Standard Care
May 15, 2021 — The anticoagulant apixaban (Eliquis) was not superior to standard of care following transcatheter aortic…
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There is a trend in interventional cardiology that is now being called “renalism,” where patients with poor renal function are being excluded from interventional procedures because they are automatically considered too high risk. However, some hospitals are also creating cardio-renal care teams so these patients can be cared for by a team of experts rather than interventional cardiologists going it alone. #SCAI21 #SCAI2021 Creating a card0-renal program.
By Dave Fornell, Editor
May 14, 2021
Creating a Cardio-renal Program to Expand Patient Volume
There is a trend in interventional cardiology that is now being called “renalism,” where patients with poor renal…
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A device programmer showing the suspension of ICD therapies (orange bar, red arrow) with iPhone 12 laying over patient’s chest (green arrow) and fluoroscopy of iPhone 12 showing the circular magnet array (yellow arrow). Image from a small study at Henry Ford Hospital. Read the full study
May 14, 2021
FDA Warns Magnets in Cell Phones and Smart Watches May Affect Pacemakers and Other EP Devices
May 14, 2021 — The U.S. Food and Drug Administration (FDA) is advising patients and caregivers to keep any consumer…
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Abbott Recalls Assurity and Endurity Pacemakers 
May 14, 2021
Abbott Recalls Assurity and Endurity Pacemakers 
May 14, 2021 — Abbott is recalling a subset of Assurity and Endurity pacemakers built using specific manufacturing…
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According to the CDC, if you are fully vaccinated you can start doing many things that you had stopped doing because of the pandemic. Infographic courtesy of the CDC.
May 13, 2021
CDC Updates Its Mask Recommendations
May 13, 2021 — The Centers for Disease Control and Prevention (CDC) just released a new statement relaxing the…
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Explaining the Emory TMVR angle. Discordance between mitral annular centerline (yellow lines) and valve orientation imposed by guidewire position within the LV apex (red dashed lines). (B) Valve intrinsic angle (α) is determined by external skirt height. (C) When annular-apical “Emory” angle (red curves) exceeds α (blue curve), annular skirt apposition is not possible, causing PVL (red arrows). (D) The valve is oriented perpendicular to the annual plane using an exteriorized apical guidewire.
By Dave Fornell, Editor
May 13, 2021
The Emory Angle Can Help Eliminate Paravalvular Leak in Transcatheter Mitral Interventions
The mitral valve anatomy is extremely complex, which has caused many challenges for transcatheter mitral valve…
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Estimates of excess deaths, defined as the number of persons who have died from all causes, above the expected number of deaths for a given place and time, can provide a comprehensive account of mortality likely related to the COVID-19 pandemic, including deaths that are both directly and indirectly associated with COVID-19
May 13, 2021
CDC Update on Excess Deaths Associated with the COVID-19 Pandemic
May 13, 2021 — Estimates of excess deaths, defined as the number of persons who have died from all causes, above the…
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PolyVascular, leading the effort to improve children's lives with a novel polymeric transcatheter valve (PTV) for children, announced that it was awarded a $2 million Small Business Innovation Research (SBIR) Phase II grant earlier this year to bring its polymeric stent-mounted valve (SMV) to clinical trials within the next two years in an effort to address pediatric congenital heart disease (CHD), which affects over 1 million patients around the world.
May 13, 2021
PolyVascular Awarded $2 Million Small Business Innovation Research Grant to Bring the First Polymer-Based Heart Valve for Children to Clinical Trials
May 13, 2021 — PolyVascular, leading the effort to improve children's lives with a novel polymeric transcatheter valve…
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