Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

Bempedoic acid becomes the first ATP citrate lyase inhibitor and first oral non-statin to meet the major adverse cardiovascular events (MACE-4) primary endpoint
News | Cardiovascular Clinical Studies
Esperion Announces CLEAR Cardiovascular Outcomes Trial of NEXLETOL (bempedoic acid) Meets Primary Endpoint

December 8, 2022 — Esperion announced that the landmark Cholesterol Lowering via Bempedoic acid, an ACL-Inhibiting Regim ...

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Allogeneic CardiALLO therapy for heart failure to complement autologous cell therapy currently enrolling in Phase III CardiAMP Heart Failure clinical trial
News | Heart Failure
BioCardia Announces FDA Approval of IND Application for Allogeneic NK1R+ Human Mesenchymal Stem Cells for Ischemic Heart Failure

December 7, 2022 —   BioCardia, Inc., a developer of cellular and cell-derived therapeutics for the treatment of ...

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Boston Scientific Corporation has announced the first results from the ACURATE neo2 Post Market Clinical Follow-up (PMCF) study evaluating the performance of the ACURATE neo2TM Aortic Valve System.
News | Structural Heart
Late-Breaking Post-Market Study Data Reinforce Clinical Procedural Success and Safety of the ACURATE neo2 Aortic Valve System

December 2, 2022 —  Boston Scientific Corporation has announced the first results from the ACURATE neo2 Post Market ...

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Transverse heart sections from wild type mice (WT) and transgenic mice overexpressing beta-3 adrenergic receptor in cardiomyocytes (c-hB3tg) after 3 months of aortic stenosis (transaortic constriction, TAC) or control (sham). Hypertrophy after TAC was less severe in the transgenic mice. Courtesy of CNIC
News | Heart Failure
A New Therapeutic Target for the Prevention of Heart Failure Due to Aortic Stenosis

December 1, 2022 —  Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a new ...

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Annalise.ai and Nuance announced that the global medical imaging AI company has joined the Nuance Precision Imaging Network (PIN), connecting Annalise.ai workflow orchestration and diagnostic support solutions to over 12,000 healthcare facilities worldwide.
News | ECG
HeartSciences and Rutgers University Announce Multi-Year Collaboration to Develop AI-based ECG Algorithms

December 1, 2022 —  Heart Test Laboratories, Inc. d/b/a HeartSciences, a medical technology company focused on saving ...

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A team led by UTHealth Houston's K. Lance Gould, MD, (center) used PET imaging technology (shown above) to map coronary blood flow and its outcomes among heart disease patients. (Photo by UTHealth Houston)
News | PET Imaging
PET Technology More Effective Than Angiogram at Determining Need for Coronary Stents, Bypass Surgery

December 1, 2022 —  A new method for determining whether patients with heart disease need coronary stents or bypass ...

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Boston Scientific Corporation has announced the first results from the ACURATE neo2 Post Market Clinical Follow-up (PMCF) study evaluating the performance of the ACURATE neo2TM Aortic Valve System.
News | Structural Heart
Late-Breaking Post-Market Study Data Reinforce Clinical Procedural Success and Safety of the ACURATE neo2 Aortic Valve System

November 30, 2022 — Boston Scientific Corporation has announced the first results from the ACURATE neo2 Post Market ...

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Boston Scientific Corporation has announced the first results from the ACURATE neo2 Post Market Clinical Follow-up (PMCF) study evaluating the performance of the ACURATE neo2TM Aortic Valve System.
News | Structural Heart
Medtronic’s Next-Gen Evolut FX TAVR System Shows Significant Improvement in Commissure Alignment in Real World Setting

November 30, 2022 — Medtronic’s newest generation self-expanding, transcatheter aortic valve replacement (TAVR) system ...

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BIOTRONIK announced their presentation of the one-year results from the investigator-initiated BIOPACT RCT this week
News | Drug-Eluting Balloons
One-Year BIOPACT Randomized Controlled Trial (RCT) Results Demonstrate Excellent Results for Low-Profile Passeo-18 Lux DCB

November 28, 2022 – BIOTRONIK announced the presentation of one-year ...
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Left: Echocardiogram at birth shows severe non-delamination of the tricuspid valve septal leaflet, with coaptation point near the right ventricle apex (marked with arrow). The right ventricle is small, while the right atrium is large. Right: Jaxon’s echocardiogram today shows a normal tricuspid valve position (marked with arrow) and normal sizes of the right atrium and right ventricle.
News | Pediatric Cardiology
From Severe Ebstein Anomaly to a Normal Heart

November 25, 2022 —  Jodie Votava-Smith, MD, has pulled up two side-by-side echocardiograms on her computer screen and ...

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Nicholas Pajewski, Ph.D., associate professor of biostatistics and data science at Wake Forest University School of Medicine. Credit: Wake Forest University School of Medicine
News | Hypertension
Study Highlights Importance of Long-term Management of Hypertension

November 23, 2022 — In 2015, published findings from the landmark Systolic Blood Pressure Intervention Trial (SPRINT) sh ...

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Survivors face higher risk of cardiac events that can reduce their life expectancy by decades
News | Pediatric Cardiology
Exercise Testing Detects Silent Cardiovascular Dangers Common in Pediatric Cancer Survivors

November 23, 2022 — Cardiopulmonary exercise testing (CPET) can detect underlying early signs of cardiovascular problems ...

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New research by Cedars-Sinai investigators supports evidence that social factors, such as unemployment, financial difficulties, racial discrimination and other stressors, affect an individual's health. Getty Images
News | Stroke
Racism, Stress and Stroke Outcomes

November 22, 2022 — investigators from the Department of Neurology at Cedars-Sinai have new information on stroke-relate ...

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Trial Evaluates FDA-Designated Breakthrough Therapy for Patients Who Lack Treatment Options
News | Heart Failure
Impulse Dynamics Announces First Patient Enrolled in AIM HIGHer — Implantable Device Trial to Treat Heart Failure in Higher EF Population

November 22, 2022 — Impulse Dynamics, a global medical device company dedicated to improving the lives of people with ...

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Successfully Met Primary and Secondary Endpoints, with Mean Placebo-Adjusted Reduction in Systolic Blood Pressure of 9.7 mmHg in Uncontrolled and Resistant Hypertensive Subjects at 50 mg Once Daily (p=0.01 vs. placebo)
News | Hypertension
Mineralys Therapeutics Announces Positive Topline Phase 2 Data for MLS-101 in the Target-HTN Trial Evaluating the Treatment of Uncontrolled and Resistant Hypertension

November 21, 2022 —  Mineralys Therapeutics, Inc., a private, clinical-stage biopharmaceutical company committed to ...

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