Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

Late-breaking data presented at ESC Congress 2022 and simultaneously published in The New England Journal of Medicine confirms implant procedure safety and defibrillation success

News | Heart Failure

FARXIGA Significantly Reduced the Risk of Cardiovascular Death or Worsening of Heart Failure in Patients with Mildly Reduced or Preserved Ejection Fraction in DELIVER Phase III Trial

August 29, 2022 — Detailed results from the DELIVER Phase III trial showed AstraZeneca’s FARXIGA (dapagliflozin) ...

August 29, 2022

News | Implantable Cardioverter Defibrillator (ICD)

Medtronic Extravascular ICD meets global pivotal clinical trial’s safety and effectiveness endpoints

August 29, 2022 — Medtronic plc announced that its investigational EV ICD System – a first-of-its-kind defibrillator ...

August 29, 2022

A study from the Smidt Heart Institute and Cedars-Sinai's Division of Artificial Intelligence in Medicine shows that AI was more accurate in diagnosing cardiac function than sonographers. Illustration by Getty.

News | Artificial Intelligence

Late-Breaking Heart Research: AI More Accurate Than Technicians

August 29, 2022 — In a first-of-its-kind randomized clinical trial led by researchers at the Smidt Heart Institute and ...

August 29, 2022

COVID mRNA vaccines are associated with a decreased risk of death in patients with heart failure, according to research presented at ESC Congress 2022.

News | Coronavirus (COVID-19)

COVID mRNA Vaccines are Safe in Patients with Heart Failure

August 26, 2022 — COVID mRNA vaccines are associated with a decreased risk of death in patients with heart failure ...

August 26, 2022

A new Cedars-Sinai study is the first study proven to be effective at identifying coronary artery disease patients at highest risk for sudden cardiac death. Photo by Cedars-Sinai.

News | Sudden Cardiac Arrest

Genetic Score Detects Those at Risk for Sudden Cardiac Death

August 26, 2022 — Researchers in the Smidt Heart Institute at Cedars-Sinai are one step closer to identifying patients ...

August 26, 2022

News | PET Imaging

Late Breaking Flurpiridaz Trial Results at ASNC2022

August 25, 2022 — The results of “A Phase 3, Open-label, Multicenter Study of Flurpiridaz (F18) Injection for Positron ...

August 25, 2022

Imperfect current propagation in the heart is at the root of most cardiac diseases

News | Cardiac Imaging

Measuring Currents in the Heart at Millimeter Resolution with a Diamond Quantum Sensor

August 25, 2022 — Imperfect current propagation in the heart is at the root of most cardiac diseases. Thanks to a novel ...

August 25, 2022

Dr. Jonathan Roberts is medical director of Clinical Research and Education, Interventional Cardiology for Memorial Healthcare System and program director of its Cardiology Fellowship program.

News | Heart Failure

Congestive Heart Failure Patients May Be Eligible for Treatment that Could Help Them Live Longer

August 24, 2022 — Patients diagnosed with moderate aortic stenosis and congestive heart failure may qualify to ...

August 24, 2022

The first US patient has been enrolled in the FDA SELUTION4BTK (Below-the-Knee) clinical trial evaluating SELUTION SLR, MedAlliance’s novel sirolimus-eluting balloon.

News | Drug-Eluting Balloons

First US Patient Enrolled in SELUTION SLR IDE Peripheral Study

August 23, 2022 — The first US patient has been enrolled in the FDA SELUTION4BTK (Below-the-Knee) clinical trial ...

August 23, 2022

A first-in-human multicenter trial involving Mayo Clinic used a new ablation technique for patients with ventricular tachycardia, an abnormally rapid heart rhythm that is a leading cause of sudden cardiac death worldwide

News | Implantable Cardioverter Defibrillator (ICD)

First-in-Human Trial Shows Promise for Hard-to-Treat Ventricular Tachycardia Heart Rhythms

August 18, 2022 — A first-in-human multicenter trial involving Mayo Clinic used a new ablation technique for patients ...

August 18, 2022

Histological analysis comparing the size of the heart of a normal mouse (left) and a mouse lacking the protein MKK6 (right). Image courtesy of CNIC

News | Cardiovascular Clinical Studies

CNIC Scientists Uncover Opposing Roles of p38 Proteins in Cardiac Hypertrophy

August 17, 2022 — A study carried out by scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) ...

August 17, 2022

Researchers at Ochsner Health and Tulane University School of Medicine have identified the genes that become active in carotid arteries when plaque rupture causes a stroke.

News | Stroke

Ochsner and Tulane Collaboration Uncovers What Happens to Genes Inside Artery Plaques to Trigger Strokes

August 15, 2022 — Researchers at Ochsner Health and Tulane University School of Medicine have identified the genes that ...

August 15, 2022

A new model developed by researchers can be used for a myriad of applications, most notably to evaluate the safety and efficacy of drugs on the cardiovascular system

News | Artificial Heart

Creating an 'Adult-Like' Mature Human Cardiac Tissue

August 15, 2022 — Researchers in the Biomedical Engineering Department at UConn have developed a new cardiac cell ...

August 15, 2022

Older adults with atrial cardiopathy (a major, often undetected cardiac cause of stroke) may be at increased risk of developing dementia, according to new research led by Johns Hopkins Medicine.

News | Cardiovascular Clinical Studies

Johns Hopkins Researchers Find Link Between Dementia and Atrial Cardiopathy

August 12, 2022 — Older adults with atrial cardiopathy (a major, often undetected cardiac cause of stroke) may be at ...

August 12, 2022

News | ASNC

Flurpiridaz Clinical Trial Results Will be Announced at ASNC2022

August 12, 2022 — The results of “A Phase 3, Open-label, Multicenter Study of Flurpiridaz (F18) Injection for Positron ...

August 12, 2022