Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

Robert J. Mentz, M.D., Associate Professor of Medicine, Chief, Heart Failure Section, Associate Program Director, Duke Cardiology Fellowship, Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina, image copyright Robert J. Mentz
News | AHA
TRANSFORM-HF Trial Found No Difference in Effectiveness Between 2 Common Loop Diuretics

November 8, 2022 — After hospital discharge for heart failure, people treated with either loop diuretic medication ...

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Julian D. Gillmore, M.D., Ph.D., Professor, University College London Centre for Amyloidosis, United Kingdom, image copyright University College London Centre for Amyloidosis
News | AHA
Novel Gene-Editing Therapy Shows Promise For Patients With Transthyretin Amyloid Cardiomyopathy

November 8, 2022 — A single IV infusion of NTLA-2001, a novel CRISPR/Cas9-based gene editing therapy, significantly ...

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Clinical studies presented at the American Heart Association 2022 Scientific Sessions event demonstrate compelling diagnostic and health economic value of the Zio suite of products across a range of clinical applications
News | AHA
Results of Four Studies Demonstrating Clinical, Economic Value of iRhythm’s Product Portfolio Presented at American Heart Association ’22

November 8, 2022 — iRhythm Technologies, Inc., a leading cardiovascular diagnostics and digital healthcare solutions ...

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Using coronary computed tomography angiography (CCTA) with HeartFlow’s FFRCT Analysis to evaluate suspected coronary artery disease (CAD) offers more accurate non-invasive diagnosis, fewer unnecessary tests, and higher confidence in identifying patients needing treatment
News | AHA
Late-Breaking Data Demonstrate AHA/ACC Guideline-Directed CCTA ± FFRCT Precision Pathway is Superior to Traditional Testing

November 7, 2022 — HeartFlow, Inc., the leader in revolutionizing precision heartcare, today announced new trial results ...

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A new analysis of iRhythm’s mSToPS trial, presented at the American Heart Association, reveals that Zio XT provided high value from a health economic perspective
News | AHA
New Research Confirms that Zio by iRhythm Provides High Value From a Health Economic Perspective

November 7, 2022 — iRhythm Technologies, Inc., a leading cardiovascular diagnostics and digital healthcare solutions ...

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Petr Ostadal, M.D., Ph.D., Professor of Medicine, Department of Cardiology, Na Homolce Hospital, Czech Republic. Image copyright Na Homolce Hospital
News | AHA
Early Use of ECMO devices Did Not Improve Outcomes in People With Cardiogenic Shock

November 7, 2022 — The immediate use of veno-arterial mechanical circulatory extracorporeal membrane oxygenation (ECMO) ...

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Study Advances Efforts to Launch CARDIALYTICS Suite of Analytic Tools
News | EP Lab
CathVision Announces Initiation of Clinical Study Evaluating Signal Complexity Algorithm

Nov. 4, 2022 — CathVision, a medical technology company developing innovative electrophysiology solutions to enhance ...

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Late-breaking clinical presentations at VIVA show IN.PACT Admiral drug-coated PTA balloon catheter outperforms bare metal stents; maintains performance in real-world setting
News | VIVA
Clinical Studies Show Medtronic Drug Coated Balloon Outperforms Bare Metal Stents; Maintains Performance in Real World

November 3, 2022 — Medtronic, a global leader in medical technology, today announced the results of two clinical studies ...

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A mouse heart with immune infiltrates leading to ICI-myocarditis. Image courtesy of UCSF
News | Coronavirus (COVID-19)
Study Sheds Light on the Reasons Behind Sex Differences in Myocarditis

November 3, 2022 — In the past several years, myocarditis has been of public interest because of cases associated with ...

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Fig. 1. Selective reduction of succinyl-CoA among the TCA cycle metabolites in cardiac muscle during chronic HF. Relative levels of the TCA cycle metabolites in cardiac muscles isolated from myocardial infarction (MI) mice, compared with those from sham mice, 28 d after surgery. Each data point in the dot plot represents one individual mouse sample (n = 38 for both groups for all metabolites, except for succinyl-CoA in which n = 18 for both groups). Concentrations of succinyl-CoA in these samples were 2.2–5
News | Heart Failure
How Heart Failure Disrupts the Cell's Powerhouse

November 3, 2022 — Chronic heart failure causes the cell’s powerhouses to dysfunction, in part due to overconsumption of ...

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Videos | TCT
VIDEO: Clinical Science in Structural Heart Disease

At TCT 2022, Jane Leopold, MD, a cardiologist at Brigham and Women’s Hospital; Director, Women's Interventional ...

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After mRNA vaccination, adults under 40 have a slightly greater chance of developing myocarditis or pericarditis, yet the vaccine’s benefits outweigh the risks, according to the American Journal of Preventive Medicine
News | Coronavirus (COVID-19)
Getting to the Heart of COVID-19 Vaccination and its Cardiovascular Risks

November 2, 2022 —  A comprehensive review and meta-analysis of published research confirm that young adults (40 years ...

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2D model showing how the pluripotent stem cells react to human relevant doses of cadmium over 8 days. From the control in the first panel, to the last panel, researchers can see how the differentiation to cardiomyocytes is inhibited with different doses of cadmium.
News | Congenital Heart
New 3D Model Shows How Cadmium Exposure May Affect Heart Development

November 2, 2022 —  Researchers have developed a three-dimensional model that shows how exposure to cadmium might lead ...

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News | VIVA
VIVA Foundation Symposium presents Clinical Trial Findings

November 2, 2022 — The second round of late-breaking clinical trial results were announced at VIVA22 on Nov. 1 in Las ...

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News | VIVA
The VEINS/VIVA 2022 Top Awards Recognize Leaders in Vascular Medicine

November 2, 2022 — A number of awards of distinction were presented during The VEINS (Venous Endovascular INterventional ...

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