Familial chylomicronemia syndrome (FCS) is a rare, genetic disease characterized by mutations in genes affecting the production or functionality of lipoprotein lipase (LPL), an enzyme necessary for the metabolism of triglycerides (TG). People living with FCS can present with severe hypertriglyceridemia (HTG) and an elevated risk of TG-induced pancreatitis. Apolipoprotein C-III (apoC-III), a 79 amino acid glycoprotein that is synthesized principally in the liver, is a key regulator of serum TG.