Pharmaceuticals

This channel includes news and new technology innovations for cardiovascular pharmaceutics. This includes antiplatelet agents, anticoagulation drugs, INR testing, NOAC, OAC, IV administered drugs such as Heprin, and dual antiplatelet therapy.

Examples of COVID-19 caused clotting with multiple pulmonary embolisms (PE) in left image, and a large thrombus in the aortic arch. Images courtesy of RSNA and Margarita Revzin et al. Find more clinical images of COVID.

News | Coronavirus (COVID-19)

Antiplatelet Drug Class Does Not Increase Survival in Hospitalized Moderate COVID-19 Cases

November 23, 2021 — The antiplatelet drug class of P2Y12 inhibitors that block the activity of platelets and prevents ...

November 23, 2021

News | Venous Therapies

Early Thrombosis After Iliac Stenting for Venous Outflow Occlusion Is Related to Disease Severity and Type of Anticoagulation

November 22, 2021 — Fewer than 10 days of low-molecular-weight heparin (LMWH) after stenting for extensive iliofemoral ...

November 22, 2021

Videos | Pharmaceuticals

VIDEO: Novel Therapeutics for Lowering Lipids

Susan Cheng, M.D., MPH, director of the Institute for Research on Healthy Aging in the Department of Cardiology at ...

November 22, 2021

EMPULSE Trial showed hospitalized adults taking empagliflozin had reduced rates of death or re-hospitalization due to acute heart failure. #AHA Heart Failure

News | Heart Failure

Adults With Acute Heart Failure Benefit When Treated With a Type 2 Diabetes Medication

November 19, 2021 — Adults treated with empagliflozin during hospitalization for acute heart failure experienced a ...

November 19, 2021

Rafael Díaz,M.D., director of Estudios Clínicos Latinoamérica in Rosario, Argentina

News | Coronavirus (COVID-19)

Prescription Omega-3 Pill Did Not Affect Outcome for Non-hospitalized Adults With COVID-19

November 19, 2021 — A high dose of a purified omega-3 fatty acid, available by prescription only, was well tolerated ...

November 19, 2021

Oral PCSK9 Inhibitor Lowering Cholesterol in First Human Trial

News | Pharmaceuticals

Oral PCSK9 Inhibitor Safe and Effective in Lowering Cholesterol in First Human Trial

November 19, 2021 — Results from two early clinical studies show the first version of an oral PCSK9-inhibitor ...

November 19, 2021

Coronary Artery Bypass Grafting (CABG). #AHA21

News | Cardiovascular Surgery

Moderna Announces Positive Data from Phase 2 Study of mRNA VEGF-A in Patients Undergoing CABG

November 18, 2021 — Moderna Inc. announced positive data from the AstraZeneca-led Phase 2 (EPICCURE) study evaluating ...

November 18, 2021

Cardiovascular Surgery Ticagrelor - significant increase in bleeding when people had bypass surgery after two to three days of discontinuing ticagrelor. #AHA #AHA21

News | Cardiovascular Surgery

Time From Stopping Blood Thinner To Bypass Surgery May Be Shortened for Select Patients

November 18, 2021 — People who are on the antiplatelet medication ticagrelor and need coronary artery bypass surgery may ...

November 18, 2021

Taking daily low-dose aspirin for seven years did not affect the risk of dementia or mental decline among adults with type 2 diabetes, according to the late-breaking ASCEND study presented at the American Heart Association’s Scientific Sessions 2021. Type 2 Diabetes and Aspirin Regimen. #AHA

News | Antiplatelet and Anticoagulation Therapies

Long-term, Low-dose Aspirin Did Not Affect Risk of Dementia in Adults With Type 2 Diabetes

November 17, 2021 — Taking daily low-dose aspirin for seven years did not affect the risk of dementia or mental decline ...

November 17, 2021

Canagliflozin, a medication used to treat type 2 diabetes, was found to greatly improve symptoms and quality of life within 3 months for people with heart failure due to either reduced or preserved cardiac function, even if they didn’t also have type 2 diabetes, according to the late-breaking CHIEF-HF study presented at the American Heart Association’s Scientific Sessions 2021. Type 2 Diabetes Canagliflozin 100mg Tablet.

News | Heart Failure

Heart Failure Symptoms Improved With a Type 2 Diabetes Medicine in Fully Remote Trial

November 17, 2021 — Canagliflozin, a medication used to treat type 2 diabetes, was found to greatly improve symptoms and ...

November 17, 2021

News | Pharmaceuticals

Bempedoic Acid Alone Lowered LDL-C Levels Comparable to Moderate or High-intensity Statin

November 15, 2021 — Esperion announced the presentation of three abstracts highlighting Nexletol tablets at the American ...

November 15, 2021

News | Pharmaceuticals

Inclisiran Reduced LDL-C in Obese Patients

November 15, 2021 — Novartis announced results from a pooled post-hoc analysis of Phase III ORION-9, -10 and -11 trials ...

November 15, 2021

Antiplatelet Plavix (Clopidogrel). OPT-PEACE trial found that nearly all patients receiving antiplatelet therapy developed evidence of abnormal gastrointestinal (GI) mucosal findings on capsule endoscopy. GettyImages

News | Antiplatelet and Anticoagulation Therapies

Most PCI Patients on Antiplatelet Therapy Developed Abnormal Gastrointestinal Findings

November 9, 2021 — Utilizing a magnetically-controlled capsule endoscopy system, the double-blind, randomized OPT-PEACE ...

November 09, 2021

A Johns Hopkins Medicine study of nearly 4,500 patients hospitalized with COVID-19 suggests that statins — medications widely used to control cholesterol — are not helpful in reducing COVID-related mortality or the severity of the illness. Graphic created by M.E. Newman, Johns Hopkins Medicine

News | Coronavirus (COVID-19)

Statins Likely Not Helpful In Reducing COVID Mortality or Severity

November 5, 2021 — In the worldwide effort to battle COVID-19 (SARS-CoV-2), researchers have often turned to medications ...

November 05, 2021

Katherine Fornell, age 5, from suburban Chicago, receives her first dose of the COVID-19 vaccine during the first week it became available in the U.S. The FDA authorized the emergency use of the Pfizer-BioNTech COVID-19 vaccine Oct. 29 for the prevention of COVID-19 in children 5 to 11 years of age. This was based on a safety review of more than 3,000 patients receiving the vaccine ages 5-11.

Feature | Coronavirus (COVID-19)

FDA Authorizes Pfizer-BioNTech COVID-19 Vaccine for Children Ages 5-11

November 5, 2021 — The U.S. Food and Drug Administration (FDA) authorized the emergency use of the Pfizer-BioNTech COVID ...

November 05, 2021