Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

The Abiomed Impella was highlighted in several sessions at the 2020 TCT Connect conference. #TCT #TCT2020 #TCTconnect

News | Hemodynamic Support Devices

Restore EF Study Demonstrates Impella Supported High-Risk PCI Improves Left Ventricular Ejection Fraction

October 16, 2020 — The Restore EF Study demonstrates the use of contemporary best practices, including attempting a more ...

October 16, 2020

The Keystone Heart TriGuard 3 (TG3) is a self-stabilizing cerebral embolic deflection filter used in patients undergoing transcatheter aortic valve replacement (TAVR). The device is designed to reduce TAVR complications of cerebral embolization and ischemic stroke. #TCT #TCT2020 #TCTconnect

News | Heart Valve Technology

Keystone Heart TAVR Embolic Protection Device Did Not Demonstrate Superiority

October 15, 2020 – The REFLECT II randomized clinical trial evaluating the safety and efficacy of the Keystone Heart ...

October 15, 2020

The Boston Scientific Acurate neo self-expanding TAVR valve (left) did not perform as well clinically as the Medtronic CoreValve Evolut TAVR valve (right) in the SCOPE II trial presented at TCT 2020. #TCT #TCT2020 #TCTconnect

Feature | Heart Valve Technology

Acurate neo TAVR Valve Fails to Meet Noninferiority With Medtronic CoreValve Evolut

October 15, 2020 – The SCOPE II trial comparing the Boston Scientific Acurate neo vs. Medtronic CoreValve Evolut TAVR ...

October 15, 2020

An illustration showing the MitraClip catheter entering the left atrium through a transseptal puncture. #TCT2020 #TCTconnect

News | Heart Valve Technology

Transcatheter Closure of Residual ASD After Transcatheter Mitral Valve Repair Was Not Superior to Medical Therapy

October 15, 2020 – The MITHRAS randomized clinical trial found that interventional closure of an iatrogenic atrial ...

October 15, 2020

News | Coronavirus (COVID-19)

Effect of COVID-19 on Cardiology Highlighted in Research at ACC Quality Summit

October 14, 2020 — American College of Cardiology (ACC) Quality Summit virtual meeting Oct. 8-9, 2020, featured several ...

October 14, 2020

Medtronic is starting a randomized, head-to-head study comparing the Medtronic CoreValve Evolut Pro and Pro+TAVR Systems against the balloon-expandable Edwards Sapien 3 and Sapien 3 Ultra Transcatheter Heart Valvestwo transcatheter aortic valve replacement (TAVR) systems in patients with severe symptomatic aortic stenosis (ssAS).

News | Heart Valve Technology

Medtronic Launches Head-to-Head TAVR Study Comparing the Corevalve Evolut vs Edwards Sapien in Small Annulus Patients

October 14, 2020 — Medtronic announced it is starting a randomized, head-to-head study comparing two transcatheter ...

October 14, 2020

News | Coronavirus (COVID-19)

COVID-19 Positive STEMI Patients Have Higher Mortality

October 14, 2020 – The first outcomes data from the North American COVID-19 ST-Segment Elevation Myocardial Infarction ...

October 14, 2020

Chest X-ray of a congestive heart failure patient, showing fluid in the lower portions of the lungs and an enlarged heart. Getty Images

News | Heart Failure

ACC and Novartis Collaborate to Optimize Heart Failure Care With TRANSFORM Study

October 5, 2020 — The American College of Cardiology (ACC) says heart failure (HF) is a cardiovascular epidemic. In ...

October 05, 2020

News | VIVA

The Latest Vascular Interventional Clinical Data Presented at VIVA 2020

October 5, 2020 — The Vascular Interventional Advances (VIVA) virtual conference will feature 10 late-breaking clinical ...

October 05, 2020

Very ill COVID-19 patients have a high rate of in-hospital sudden cardiac arrest and a very low survival rate.

Feature | Coronavirus (COVID-19)

Cardiac Arrest With Poor Survival Common in Sickest COVID-19 Patients

October 2, 2020 — Even when a sudden cardiac arrest happens inside a top hospital, where a code blue team is readily ...

October 02, 2020

An example of a CT coronary artery calcium scoring exam showing how each vessel segment is scored to assess a patient's risk for a future heart attack. Example is from Philips Healthcare.

News | Cardiac Imaging

Study Finds Removing Cost from Calcium Score Testing Increased Utilization

September 25, 2020 — A study out of University Hospitals (UH) found that removing the cost barrier for coronary artery ...

September 25, 2020

SARS-CoV-2 infection of cells shown in green, left. This is inhibited by a modified form of cholesterol called 25-hydroxycholesterol (25HC), as seen in the cells in the right image. 25HC activates an enzyme called ACAT, found inside cells in the endoplasmic reticulum. ACAT then depletes accessible cholesterol on the cell’s membrane. It is a normally occurring process that gets kicked into high gear during some viral infections. Image from UC San Diego Health Sciences.

News | Coronavirus (COVID-19)

Statins May Reduce COVID-19 Severity

September 24, 2020 — Analyzing anonymized patient medical records, University of California (UC) San Diego Health resear ...

September 24, 2020

TCT 2020 Late-breaking Study trial Presentations Announced. #TCTconnect #TCT2020 #TCT

Feature | TCT

TCT 2020 Late-breaking Study Presentations Announced

October 15, 2020 — The late-breaking studies are one of the hallmarks of the annual Transcatheter Cardiovascular ...

October 15, 2020

The NIH is heading three studies looking at various blood thinners and anticoagulants to treat COVID-19 patients with VTE.

News | Coronavirus (COVID-19)

NIH Trials Evaluate Various Blood Thinners to Treat COVID-19

September 11, 2020 — The National Institutes of Health (NIH) has launched two of three adaptive clinical trials ...

September 11, 2020

Medtronic announced U.S. Food and Drug Administration (FDA) approval of an early feasibility study (EFS) of the Intrepid Transcatheter Tricuspid Valve Replacement (TTVR) system. The study begins on the heels of a recent Breakthrough Device Designation issued by the FDA for the Intrepid TTVR System. The Intrepid TTVR system is an investigational device worldwide.

News | Heart Valve Technology

Medtronic Receives FDA Breakthrough Device Designation and Begins Trial for Intrepid Tricuspid Transcatheter Valve

September 11, 2020 – Medtronic announced U.S. Food and Drug Administration (FDA) approval of an early feasibility study ...

September 11, 2020