Heart Failure

This heart failure channel offers news and new technology to treat heart failure. This includes for new innovations to treat congestive heart failure (CHF). The channel includes news on HFpEF and HFrEF. Heart failure occurs when the heart is no longer able to pump as much blood as the body requires. This can lead to enlargement of the heart because the muscle works harder to supply blood, but the pumping is ineffective. This may be due to defects in the myocardium, such as an infarct, or due to structural issues such as severe valve regurgitation. The disease is divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or a left ventricular assist device (LVAD).

Last year, U.S. Congressman Andy Barr (KY-06) introduced this legislation in the House to honor the legacy of his wife, Carol Leavell Barr, who passed away tragically from sudden cardiac death brought on by mitral valve prolapse, an underlying heart condition that causes death in .2% of cases.

News | Heart Failure

CAROL Act Will Prioritize Research on Heart Valve Disease

December 2, 2022 — The U.S. Senate today passed the bipartisan Cardiovascular Advances in Research and Opportunities ...

December 02, 2022

Transverse heart sections from wild type mice (WT) and transgenic mice overexpressing beta-3 adrenergic receptor in cardiomyocytes (c-hB3tg) after 3 months of aortic stenosis (transaortic constriction, TAC) or control (sham). Hypertrophy after TAC was less severe in the transgenic mice. Courtesy of CNIC

News | Heart Failure

A New Therapeutic Target for the Prevention of Heart Failure Due to Aortic Stenosis

December 1, 2022 — Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a new ...

December 01, 2022

News | Cardiac Imaging

AI Predicts Heart Disease Risk Using Single X-Ray

November 29, 2022 — Researchers have developed a deep learning model that uses a single chest X-ray to predict the 10 ...

November 29, 2022

Sponsored Content

Blog | Artificial Intelligence

BLOG: AI outperforms human analysis in predicting cardiac outcomes

New research shows superiority of Ultromics’ AI in predicting cardiac-related death As the use of artificial ...

October 10, 2022

Tanya Therapeutics announced today that the US FDA has granted orphan drug designation for its second gene therapy product candidate, TN-401, for the treatment of arrhythmogenic right ventricular cardiomyopathy (ARVC)

News | Pharmaceuticals

Tenaya Therapeutics Receives Orphan Drug Designation from the U.S. Food and Drug Administration for its Gene Therapy for Genetic Arrhythmogenic Right Ventricular Cardiomyopathy

November 28, 2022 – Tenaya Therapeutics, a clinical-stage biotechnology company with a mission to discover, develop and ...

November 28, 2022

Survivors face higher risk of cardiac events that can reduce their life expectancy by decades

News | Coronavirus (COVID-19)

Study Finds That Risk of Myocarditis After SARS-CoV-2 Vaccination is Increased But Very Low

November 25, 2022 — A large study found that myocarditis after SARS-CoV-2 vaccination was rare but higher in younger ...

November 25, 2022

New research by Cedars-Sinai investigators supports evidence that social factors, such as unemployment, financial difficulties, racial discrimination and other stressors, affect an individual's health. Getty Images

News | Stroke

Racism, Stress and Stroke Outcomes

November 22, 2022 — investigators from the Department of Neurology at Cedars-Sinai have new information on stroke-relate ...

November 22, 2022

Trial Evaluates FDA-Designated Breakthrough Therapy for Patients Who Lack Treatment Options

News | Heart Failure

Impulse Dynamics Announces First Patient Enrolled in AIM HIGHer — Implantable Device Trial to Treat Heart Failure in Higher EF Population

November 22, 2022 — Impulse Dynamics, a global medical device company dedicated to improving the lives of people with ...

November 22, 2022

UH Cleveland Medical Center. Image courtesy of University Hospitals

News | Deep Vein Thrombosis (DVT)

Four Prospective, Multicenter Studies Support Use of Drug-Coated Balloons Over Bare Metal Stents in Treating Femoropopliteal Lesions

November 21, 2022 — New research published in the Journal of the American College of Cardiology shows the use of drug ...

November 21, 2022

Cardiovascular disease remains the leading cause of death in the United States (US) and worldwide, according to the American Heart Association.

News | Heart Failure

Defining preventive cardiology: A clinical practice statement from the American Society for Preventive Cardiology

November 21, 2022 — Cardiovascular disease remains the leading cause of death in the United States (US) and worldwide ...

November 21, 2022

Justin Balko, PharmD, PhD, Ingram Associate Professor of Cancer Research, and a co-corresponding author of the study. Credit: Vanderbilt University Medical Center

News | Heart Failure

Cardiac antigen identified as mechanism for heart complication with immunotherapy-related myocarditis

November 22, 2022 — Myocarditis is a complication that can occur in cancer patients treated with immune checkpoint ...

November 21, 2022

Certain adults with this artery-blocking condition may see more benefits with an open bypass compared to less-invasive procedures to improve circulation.

News | Peripheral Artery Disease (PAD)

Bypass Surgery Favorable for Initial Treatment of Chronic Limb-Threatening Ischemia

November 15, 2022 Performing open bypass surgery to restore circulation for people with a severe form of peripheral ...

November 15, 2022

UMSOM researchers display first genetically modified pig heart transplanted into living patient. Image courtesy of University of Maryland School of Medicine

News | Heart Failure

Unexpected Electrical Changes Seen in First Successful Transplant of Genetically-Modified Pig Heart

November 15, 2022 — Ten months after transplanting the first genetically-modified pig heart into a human patient ...

November 15, 2022

When it comes to heart failure (HF), sex differences are known to impact everything from risk factors to clinical presentation to response to treatment, making sex a key factor to consider in studies of emerging pharmacotherapies.

News | Heart Failure

Study Shows Heart Failure Treatment With Dapagliflozin Consistently Benefited Both Men and Women

November 14, 2022 — When it comes to heart failure (HF), sex differencesare known to impact everything from risk factors ...

November 14, 2022

Reduction in the risk of death or major bleeding after primary PCI in patients with STEMI treated with heparin monotherapy (blue curve) or bivalirudin with a post-procedure infusion (red curve). The hazard ratio of 0.69 signifies a 31% reduction in risk. The ARR (absolute risk reduction) was 1.3%. The NNT (number of patients needed to treat to prevent one death or large bleed) was 76. Image courtesy of Mount Sinai Health System

News | Antiplatelet and Anticoagulation Therapies

Bivalirudin Found to be Safer and More Effective Than Heparin for Treating Heart Attack Patients Undergoing Percutaneous Coronary Intervention

November 14, 2022 — Bivalirudin is a safer and more effective anticoagulant than heparin for treating patients with the ...

November 14, 2022

The "Trending Topics at Sessions 2022" panel of experts featured Manesh R. Patel, MD, FACC, FAHA, Chair of the Committee on AHA 2022 Scientific Sessions, to review highlights and lessons learned from the event.

News | AHA

November 14, 2022 — The American Hospital Association Scientific Sessions 2022, held Nov. 5-7 in Chicago, IL, presented ...

November 14, 2022