Cardiovascular Clinical Studies

This channel includes news and new technology innovations from cardiovascular clinical trials. These clinical studies include all cardiac subspecialties.

the Eluvia stent exhibited superiority with a primary patency rate of 85.4% versus 76.3% with BMS (p=0.0077).1 The analysis also confirmed a significantly greater rate of sustained clinical improvement without reintervention

News | Peripheral Artery Disease (PAD)

Boston Scientific Eluvia Drug-Eluting Vascular Stent System Exhibits Superiority Compared to Bare Metal Stents

October 20, 2021 — Boston Scientific Corporation announced positive data for the Eluvia Drug-Eluting Vascular Stent ...

October 20, 2021

$Cardiac CTA derived left atrium emptying fraction (LAEF) improves predictive performance of established clinical risk scores and may be used to assess TAVR patient risk during pre-procedure workup and post-procedural surveillance. These images show LAVmax (A and B), LAVmin (C and D), and LAEF using cardiac CTA. LAEF was calculated as (LAVmax-LAVmin)/LAVmax x 100. Given LAVmax of 109 mL and LAVmin of 80 mL, the LAEF was calculated to be 27%. Image courtesy of AJR.$

News | Computed Tomography (CT)

Cardiac CTA Parameters Predict Post-TAVR Mortality

October 14, 2021 — Cardiac computed tomography angiography (CTA) derived left atrium emptying fraction (LAEF) improves ...

October 14, 2021

European Society of Cardiology 2021 Late-breaking hot-line Studies presented with links.

News | ESC | By Dave Fornell, DAIC Editor

European Society of Cardiology 2021 Late-breaking Studies

October 4, 2021 — Here are links to all the late-breaking cardiology studies presented in Hot-Line sessions at the 2021 ...

October 04, 2021

News | Antiplatelet and Anticoagulation Therapies

MASTER DAPT Shows 1-month Dual Antiplatelet Therapy After Stent Benefits High Bleeding Risk Patients

October 4, 2021 — One month of dual antiplatelet therapy (DAPT) following stent implantation in high bleeding risk ...

October 04, 2021

Gadolinium-enhanced MRI of a cardiac radiation therapy patient at baseline (left) and 3 months post-treatment (right). Top: the left ventricle with patchy, gadolinium-enhanced scar was transmurally targeted with a radiation ose of 25 Gy between 3 and 6 o’clock (red brackets). Nonenhanced, remote myocardium is adjacent to target region (white arrowhead). Bottom: surviving nonenhanced myocardium within the same images is visible in the targeted region at baseline and 3 months post-treatment (yellow outline).

Feature | EP Lab

Radiation Therapy Reprograms Heart Cells to Younger State

September 28, 2021 — New research from Washington University School of Medicine in St. Louis suggests that radiation ...

September 28, 2021

CardioMEMS is a wireless, battery-free sensor that is implanted into the pulmonary artery via a right heart catheterization procedure to transmit pulmonary artery pressures.

News | Heart Failure

GUIDE-HF Trial Shows Hemodynamic Guided Management Benefits Larger Heart Failure Population

September 28, 2021 — Hemodynamic guided management using the CardioMEMS device may reduce heart failure hospitalizations ...

September 28, 2021

Illustration of the Watchman transcatheter left atrial appendage (LAA) occluder being deployed into the LAA. FDA is concerned about higher rates of LAA occlusion complications in women compared to men, prompting the FDA to send a letter to providers warning them on possible poor outcomes.

Feature | Left Atrial Appendage (LAA) Occluders

FDA Concerned About Higher Rates of LAA Occlusion Complications in Women

September 27, 2021 — Compared with men undergoing left atrial appendage occlusion (LAAO), women have a significantly ...

September 27, 2021

Siemens Artis Q angiography system #ESC #ESCcongress

News | Sudden Cardiac Arrest

TOMAHAWK Trial Does Not Support Early Coronary Angiography in Cardiac Arrest Without ST-elevation

September 13, 2021 — Early coronary angiography in out-of-hospital cardiac arrest (OHCA) patients without ST-segment ...

September 13, 2021

News | FFR Technologies

Systematic FFR Assessment Did Not Add Benefit During Diagnostic Angiography

September 8, 2021 — Adding systematic fractional flow reserve (FFR) assessment to coronary angiography does not reduce ...

September 08, 2021

A 3-D CT reconstructed image showing a narrow lesion at the carotid bifurcation. ACST-2 was the largest trial to compare the long-term effect of carotid artery stenting (CAS) and carotid endarterectomy (CEA) on stroke in asymptomatic patients with a severely narrowed carotid artery that had not yet caused a stroke. Image by Canon

News | Stroke

Carotid Surgery Versus Stenting Have Similar Long-term Effects on Stroke

September 7, 2021 — Carotid artery surgery and stenting have comparable long-term effects on fatal or disabling stroke i ...

September 07, 2021

The Medtronic Reveal Linq implantable cardiac monitor (ICM) was used in the SMART-MI study. It is inserted under the skin in a simple, fast outpatient procedure. The device is smaller than a AAA battery.

News | Implantable Cardiac Monitor (ICM)

Implantable Cardiac Monitors Predict Complications in Selected Post-myocardial Infarction Patients

September 7, 2021 — Remote monitoring of implantable cardiac monitors (ICMs) is highly effective for early detection of ...

September 07, 2021

COVID in cardiology was again a key driver of content pageviews on DAIC in August 2021. Also, a key new technology that cardiologists had a lot of interest in was the release of 3D/4D intra-cardiac echocardiography (ICE) to better guide EP and structural heart procedures without the need for transesophageal echo and its associated need for deep anesthesia.

Feature | By Dave Fornell, Editor

September 3, 2021 — Here is the list of the most popular content on the Diagnostic and Interventional Cardiology (DAIC) ...

September 03, 2021

Drones Could Deliver Defibrillators or AEDs to sudden Cardiac Arrest Victims Faster Than Ambulances. Getty Images

Feature | Sudden Cardiac Arrest

Drones Could Deliver Defibrillators to Cardiac Arrest Victims Faster Than Ambulances

September 1, 2021 — The world’s first feasibility study has found that drones can be used to deliver life-saving defibri ...

September 01, 2021

News | Antiplatelet and Anticoagulation Therapies

One-month Clopidogrel Monotherapy After PCI Not Supported in STOPDAPT-2 ACS Trial

September 1, 2021 — The STOPDAPT-2 ACS trial does not support the use of one month of dual antiplatelet therapy (DAPT) ...

September 01, 2021

The anticoagulant edoxaban (Savaysa) may be just as effective as warfarin for preventing heart attack or stroke in patients with AFib who undergo transcatheter aortic valve replacement (TAVR), according to an ESC late-breaking trial.

News | Antiplatelet and Anticoagulation Therapies

Edoxaban May Be Effective Treatment for Atrial Fibrillation After TAVR

September 1, 2021 – The anticoagulant edoxaban (Savaysa) may be just as effective as warfarin for preventing heart ...

September 01, 2021

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