The mechanism of action for mavacamten, a cardiac myosin inhibitor to treat obstructive hypertrophic cardiomyopathy (oHCM). EXPLORER-HCM trial #ACC21 #ACC2021
May 15, 2021
Mavacamten Is Effective in Treating Obstructive Hypertrophic Cardiomyopathy
May 15, 2021 — A new analysis of the Phase 3 EXPLORER-HCM study evaluating mavacamten, an investigational, first-in-…
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The combination heart failure drug sacubitril/valsartan did not significantly reduce the rate of heart failure or cardiovascular death following a heart attack compared to ramipril, an angiotensin converting enzyme (ACE) inhibitor. #ACC21 #ACC2021
May 15, 2021
Sacubitril/Valsartan Does Not Outperform ACE Inhibitor in Preventing Heart Failure After Heart Attack
May 15, 2021 — The combination heart failure drug sacubitril/valsartan (Entresto) did not significantly reduce the rate…
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In the LAAOS III trial, surgeons could seal off the LAA during the open heart procedure using sutures, staples or approved closure devices. The image shows a SentraHeart lasso type LAA occluder about to seal off the LAA from the outside of the heart. #ACC21 #ACC2021
May 15, 2021
Left Atrial Appendage Occlusion Reduces Stroke After Heart Surgery
May 15, 2021 — Patients with an elevated risk of stroke due to heart rhythm problems, or atrial fibrillation (AFib),…
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The ADAPTABLE trial found no significant differences in cardiovascular events or major bleeding in patients with pre-existing cardiovascular disease who were taking 81 milligrams (mg) baby aspirin, versus 325 mg of daily aspirin. Getty Images #ACC #ACC21 #ACC2021
May 15, 2021
Baby and Regular Strength Aspirin Equal in Cardiac Platelet Inhibition and Safety
May 15, 2021 — The ADAPTABLE trial found no significant differences in cardiovascular events or major bleeding in…
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An Edward Lifesciences Sapien TAVR valve during an implant procedure on angiography. There are still questions on how to best anticoagulate TAVR patients and the ATLANTIS study found Eloquis is not a good solution.
May 15, 2021
TAVR Anticoagulation With Apixaban Not Superior to Standard Care
May 15, 2021 — The anticoagulant apixaban (Eliquis) was not superior to standard of care following transcatheter aortic…
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There is a trend in interventional cardiology that is now being called “renalism,” where patients with poor renal function are being excluded from interventional procedures because they are automatically considered too high risk. However, some hospitals are also creating cardio-renal care teams so these patients can be cared for by a team of experts rather than interventional cardiologists going it alone. #SCAI21 #SCAI2021 Creating a card0-renal program.
By Dave Fornell, Editor
May 14, 2021
Creating a Cardio-renal Program to Expand Patient Volume
There is a trend in interventional cardiology that is now being called “renalism,” where patients with poor renal…
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A device programmer showing the suspension of ICD therapies (orange bar, red arrow) with iPhone 12 laying over patient’s chest (green arrow) and fluoroscopy of iPhone 12 showing the circular magnet array (yellow arrow). Image from a small study at Henry Ford Hospital. Read the full study
May 14, 2021
FDA Warns Magnets in Cell Phones and Smart Watches May Affect Pacemakers and Other EP Devices
May 14, 2021 — The U.S. Food and Drug Administration (FDA) is advising patients and caregivers to keep any consumer…
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Abbott Recalls Assurity and Endurity Pacemakers 
May 14, 2021
Abbott Recalls Assurity and Endurity Pacemakers 
May 14, 2021 — Abbott is recalling a subset of Assurity and Endurity pacemakers built using specific manufacturing…
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According to the CDC, if you are fully vaccinated you can start doing many things that you had stopped doing because of the pandemic. Infographic courtesy of the CDC.
May 13, 2021
CDC Updates Its Mask Recommendations
May 13, 2021 — The Centers for Disease Control and Prevention (CDC) just released a new statement relaxing the…
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Explaining the Emory TMVR angle. Discordance between mitral annular centerline (yellow lines) and valve orientation imposed by guidewire position within the LV apex (red dashed lines). (B) Valve intrinsic angle (α) is determined by external skirt height. (C) When annular-apical “Emory” angle (red curves) exceeds α (blue curve), annular skirt apposition is not possible, causing PVL (red arrows). (D) The valve is oriented perpendicular to the annual plane using an exteriorized apical guidewire.
By Dave Fornell, Editor
May 13, 2021
The Emory Angle Can Help Eliminate Paravalvular Leak in Transcatheter Mitral Interventions
The mitral valve anatomy is extremely complex, which has caused many challenges for transcatheter mitral valve…
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Estimates of excess deaths, defined as the number of persons who have died from all causes, above the expected number of deaths for a given place and time, can provide a comprehensive account of mortality likely related to the COVID-19 pandemic, including deaths that are both directly and indirectly associated with COVID-19
May 13, 2021
CDC Update on Excess Deaths Associated with the COVID-19 Pandemic
May 13, 2021 — Estimates of excess deaths, defined as the number of persons who have died from all causes, above the…
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PolyVascular, leading the effort to improve children's lives with a novel polymeric transcatheter valve (PTV) for children, announced that it was awarded a $2 million Small Business Innovation Research (SBIR) Phase II grant earlier this year to bring its polymeric stent-mounted valve (SMV) to clinical trials within the next two years in an effort to address pediatric congenital heart disease (CHD), which affects over 1 million patients around the world.
May 13, 2021
PolyVascular Awarded $2 Million Small Business Innovation Research Grant to Bring the First Polymer-Based Heart Valve for Children to Clinical Trials
May 13, 2021 — PolyVascular, leading the effort to improve children's lives with a novel polymeric transcatheter valve…
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Abbott recently announced its new interventional imaging platform powered by Ultreon 1.0 Software, has gained European CE marked. This first-of-its-kind imaging software merges optical coherence tomography (OCT) intravascular imaging with the power of artificial intelligence (AI) for enhanced visualization. The new Ultreon Software can automatically detect the severity of calcium-based blockages and measure vessel diameter to enhance the precision of physicians’ decision-making during coronary stenting proc
May 12, 2021
Abbott’s New Artificial Intelligence OCT Coronary Imaging Platform Launches in Europe
May 12, 2021 — Abbott recently announced its new interventional imaging platform powered by Ultreon 1.0 Software, has…
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According to the British Heart Foundation, heart and circulatory diseases cause more than a quarter (27 percent) of all deaths in the UK, which equates to more than 160,000 deaths each year — or one death every three minutes.
May 12, 2021
Using Contrast MRI After a Heart Attack Could Increase Survival
May 12, 2021 — According to the British Heart Foundation, heart and circulatory diseases cause more than a quarter (27…
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Preliminary results of a clinical trial, presented today at the AATS 101st Annual Meeting, showed that a new, low-profile thoracic aortic endograft is safe and effective in the treatment of descending thoracic aortic aneurysm or penetrating atherosclerotic ulcer (PAU) diseases.
May 12, 2021
Low Profile Thoracic Aortic Endograft Device Reduces Complications and Expands Patient Pool
May 12, 2021 — Preliminary results of a clinical trial, presented today at the AATS 101st Annual Meeting, showed that a…
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EP lab at the University of Colorado
May 12, 2021
Pulsed Electric Field Focal Ablation Catheter From Galaxy Medical and Japan Life Will Seek FDA Clearance 
May 12, 2021 — Galaxy Medical and Japan Lifeline announced an exclusive distribution agreement for the Alpha1 ablation…
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The digital technology is reducing reliance on unnecessary invasive diagnostic procedures and is cutting hospital waiting times
May 12, 2021
NICE Renews Support for Use of AI-powered HeartFlow Analysis
May 12, 2021 — HeartFlow, Inc., a leader in revolutionizing precision heartcare, today announced that the National…
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The BioCardia cardiac stem cell CardiAMP trial is a Phase III study looking at the efficacy of using stem cells to improve heart function in heart failure patients. It is the first trial for this technology to reach Phase III trial.
By Simon H. Stertzer, M.D.
May 11, 2021
Is Cardiac Cell Therapy Worth Another Look?
Heart failure remains an unheralded global pandemic, costing society billions of dollars each year.[1,2] Projections…
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The American Institute of Ultrasound in Medicine (AIUM) and the American Society of Echocardiography (ASE) have joined the International Contrast Ultrasound Society (ICUS) in recognizing the relatively low risk and important clinical benefits of ultrasound contrast agents (UCAs), which are used routinely around the world to help detect heart disease, stratify the risk of heart attack or stroke, identify and characterize tumors throughout the abdomen, and monitor the effectiveness of cancer therapies in adul
May 11, 2021
Medical Societies Support Safety and Benefits of Ultrasound Contrast Agents
May 11, 2021 — The American Institute of Ultrasound in Medicine (AIUM) and the American Society of Echocardiography (…
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Patients hospitalized with COVID-19 may be at risk of developing heart failure even if they do not have a previous history of heart disease or cardiovascular risk factors, a new Mount Sinai study shows. 
May 11, 2021
Patients Hospitalized With COVID-19 Have a Small Risk of Heart Failure
May 11, 2021 — Patients hospitalized with COVID-19 may be at risk of developing heart failure even if they do not have…
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