Heart Failure

This heart failure channel offers news and new technology to treat heart failure. This includes for new innovations to treat congestive heart failure (CHF). The channel includes news on HFpEF and HFrEF. Heart failure occurs when the heart is no longer able to pump as much blood as the body requires. This can lead to enlargement of the heart because the muscle works harder to supply blood, but the pumping is ineffective. This may be due to defects in the myocardium, such as an infarct, or due to structural issues such as severe valve regurgitation. The disease is divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant  or a left ventricular assist device (LVAD).

Videos | Artificial Intelligence | July 10, 2018
Partho Sengupta, M.D., DM, FACC, FASE, chief division of cardiology, director of cardiac imaging, West Virginia...
New Tool Predicts Benefits and Risks of Implantable Defibrillator for Heart Failure Patients
News | Implantable Cardioverter Defibrillator (ICD) | July 02, 2018
July 2, 2018 — University of Washington (UW) Medicine cardiologists have developed a tool to predict which heart...
New Target for Treating Heart Failure Identified by Penn Medicine Researchers

Microtubules in heart cells from a healthy patient (left) and from a patient with heart failure. The dense network of detyrosinated microtubules impedes the motion of the failing heart cell during the heart beat. Credit: Ben Prosser lab, Perelman School of Medicine, University of Pennsylvania

News | Heart Failure | June 25, 2018
June 25, 2018 — New research finds changes in cellular struts called microtubules (MT) can affect the stiffness of...
The Medtronic HeartWare Ventricular Assist Devices (HVAD) has a Class I FDA recall.
Feature | Ventricular Assist Devices (VAD) | June 04, 2018
June 4, 2018 — The U.S. Food and Drug Administration said Medtronic initiated a Class 1 recall all 204,017 of its...
Gencaro Does Not Reduce Atrial Fibrillation Risk in Heart Failure Patients
News | Heart Failure | May 30, 2018
May 30, 2018 — Data from the GENETIC-AF trial was presented in a “Late Breaking Clinical Trials” oral presentation at...
Abbott Recalls the HeartMate 3 Left Ventricular Assist System, LVAD
News | Ventricular Assist Devices (VAD) | May 23, 2018
May 23, 2018 — Abbott has initiated a Class I recall of the HeartMate 3 Left Ventricular Assist System due to a...
Medtronic AdaptivCRT Feature Associated with Improved Heart Failure Patient Survival
News | Cardiac Resynchronization Therapy Devices (CRT) | May 22, 2018
May 22, 2018 — Medtronic plc announced study results showing its AdaptivCRT algorithm is associated with improved...
Cardiac Contractility Modulation Safe and Effective as Heart Failure Treatment

Image courtesy of Impulse Dynamics

News | Heart Failure | May 18, 2018
May 18, 2018 — In a new study, cardiac contractility modulation (CCM) therapy was confirmed to significantly improve...
V-Wave Closes $70M Financing to Support Pivotal Study of Heart Failure Therapy
News | Heart Failure | May 16, 2018
May 16, 2018 — Israel-based V-Wave Ltd. recently closed a $70 million Series C financing for its proprietary, minimally...
News | Heart Failure | May 14, 2018
May 14, 2018 — Ancora Heart Inc. announced the expansion of the company’s U.S. feasibility study to evaluate the...
Protein Clumping May Contribute to Heart Failure Development

A PET scan detects clumping proteins in rat hearts (top). The enlarged heart (right) is one with heart failure. Other PET scans showing blood flow in the rat hearts (bottom) show that the protein clumps aren't due to circulation problems. Image courtesy of Circulation Research, May 11, 2018.

News | Heart Failure | May 11, 2018
May 11, 2018 — A team led by Johns Hopkins University Researchers has discovered that protein clumps appear to...
Minnesota Living With Heart Failure Questionnaire Qualified for FDA Medical Device Development Tools Program

The CORolla device from Israel-based CorAssist is one example of new devices being manufactured and tested to treat heart failure. The efficacy of this and other new devices under development can now be assessed with the Minnesota Living With Heart Failure Questionnaire. 

Technology | Heart Failure | May 07, 2018
May 7, 2018 — The U.S. Food and Drug Administration (FDA) has qualified the Minnesota Living with Heart Failure...
News | Hemodynamic Support Devices | April 12, 2018
April 12, 2018 – French medical technology company CorWave announced it has been awarded almost $3.5 million in...
Pfizer Announces Positive Topline Results from Phase 3 ATTR-ACT Study
News | Pharmaceuticals | April 06, 2018
April 6, 2018 — Pfizer Inc. announced that the Tafamidis Phase 3 Transthyretin Cardiomyopathy (ATTR-ACT) study met its...
Nation's First Heart Failure and Arrhythmia Center Opening in Ohio

Image courtesy of The Ohio State University

News | Heart Failure | April 04, 2018
April 4, 2018 — The Ohio State University Wexner Medical Center will establish the nation’s first center dedicated to...