October 10, 2019 — Here are the Cardiovascular Research Foundation (CRF) 12 late-breaking trials and 16 late-breaking science presentations that were reported at the Transcatheter Cardiovascular Therapeutics (TCT) 2019 scientific symposium. TCT, the world’s premier educational meeting specializing in interventional cardiovascular medicine, it took place Sept. 25 – 29, 2019 at The Moscone Center in San Francisco.
Every year, TCT features major medical research breakthroughs and highlights the latest data on the most innovative treatments that will impact patient care and how physicians treat heart disease, the leading cause of death in the world. The studies selected examine the safety and effectiveness of minimally invasive techniques, pharmaceuticals, technologies, and devices that demonstrate potential to treat or prevent cardiovascular disease.
Late-breaking trials and science were presented in the Main Arena and highlighted during press conferences.
Overview of top TCT19 trends - 6 Hot Topics in Interventional Cardiology at TCT 2019
Image Gallery From the TCT 2019 Meeting
Thursday, Sept. 26, 2019
Late-Breaking Trials
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TWILIGHT: A Randomized Trial of Ticagrelor Monotherapy vs Ticagrelor Plus Aspirin Beginning at 3 Months in High-risk Patients Undergoing PCI. Roxana Mehran -- VIDEO: TWILIGHT Trial Shows Benefit to Ticagrelor Monotherapy After Stent Implantation — an interview with Mehran at TCT 2019.
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IDEAL-LM: A Randomized Trial of a Bioabsorbable Polymer DES With 4-Month DAPT vs a Durable Polymer DES With 12-Month DAPT in Patients With Left Main Coronary Artery Disease. Robert-Jan Van Geuns
Late-Breaking Science
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EVOLVE Short DAPT: A Single Arm Study of 3-Month DAPT in Patients at High Bleeding Risk Treated a Bioabsorbable Polymer-Based Everolimus-Eluting Stent. Ajay J. Kirtane -- VIDEO: Early Discontinuation of DAPT in High Bleeding Risk Patients With the Synergy Stent — an interview with Kirtane at TCT 2019
Friday, Sept. 27, 2019
Late-Breaking Trials
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PORTICO: A Randomized Trial of Portico vs Commercially Available Transcatheter Aortic Valves in Patients With Severe Aortic Stenosis. Gregory P. Fontana
Late-Breaking Science
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Mitral Valve-in-Valve: One-Year Outcomes of Transcatheter Mitral Valve Replacement for Degenerated Mitral Bioprotheses. Mayra Guerrero
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STS/ACC TVT Registry: MitraClip Operator Volume-Outcome Relationship in the United States. Adnan K. Chhatriwalla
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STS Registry: Mitral Valve Surgery Institutional Volume-Outcome Relationship in the United States. Vinay Badhwar
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A Propensity Score-Matched Analysis of Transcatheter Tricuspid Valve Treatment vs Medical Treatment in Patients With Severe Tricuspid Regurgitation. Maurizio Taramasso
Saturday, Sept. 28, 2019
Late-Breaking Trials
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COAPT: Three-Year Outcomes From a Randomized Trial of the MitraClip in Patients With Heart Failure and Severe Secondary Mitral Regurgitation. Michael J. Mack
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EXCEL: Five-Year Outcomes From a Randomized Trial of PCI vs CABG in Patients With Left Main Coronary Artery Disease. Gregg W. Stone
Late-Breaking Science
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MODERATO II: A Double-Blind Randomized Trial of Cardiac Neuromodulation Therapy in Patients With Hypertension. Karl-Heinz Kuck
Friday, Sept. 29, 2019
Late-Breaking Trials
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COAPT: Cost-Effectiveness Analysis From a Randomized Trial of the MitraClip in Patients With Heart Failure and Severe Secondary Mitral Regurgitation. Suzanne J. Baron
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REMEDIAL III: A Randomized Trial of Urine Flow Rate-Guided vs LVEDP-Guided Hydration in Patients at High Risk for Contrast Nephropathy. Carlo Briguori
Late-Breaking Science
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FORZA: A Randomized Trial of Fractional Flow Reserve vs Optical Coherence Tomography to Guide Revascularization of Intermediate Coronary Stenoses. Francesco Burzotta
- IVUS-XPL: Five-Year Outcomes From a Randomized Trial of Intravascular Ultrasound-Guided vs Angiography-Guided PCI of Long Coronary Lesions. Myeong-Ki Hong
Video Coverage of TCT 2019:
6 Hot Topics in Interventional Cardiology at TCT 2019
VIDEO: SCAI Prospective on Key Takeaways at TCT 2019 — Interview with Chandan Devireddy, M.D.
VIDEO: Cardiogenic Shock Initiative Continues to Reduce Mortality by 50 Percent — Interview with William O’Neill, M.D.
VIDEO: Overview of Short DAPT in High-risk Bleeding Patients Who Receive Stents — Interview with Robert Harrington, M.D.
VIDEO: The Expansion of TAVR Following the FDA Clearing its Use in All Patients — Interview with Torsten Vahl, M.D.
VIDEO: TWILIGHT Trial Shows Benefit to Ticagrelor Monotherapy After Stent Implantation — Interview with Roxana Mehran, M.D.
VIDEO: Highlighting Women Involved With Structural Heart Interventions — Interview with Vivian Ng, M.D.
VIDEO: Early Discontinuation of DAPT in High Bleeding Risk Patients With the Synergy Stent — Interview with Ajay Kirtane, M.D.
VIDEO: Justification for Hemodynamic Support in Complex PCI — Interview with Jeffrey J. Popma, M.D.
VIDEO: New PLATINUM Diversity Data Shows Early DAPT Cessation OK in Minorities With New Generation Stent — Interview with Roxana Mehran, M.D.,
VIDEO: Trends in Radial Access for Percutaneous Coronary Interventions — Interview with Sunil Rao, M.D., and Prashant Kaul, M.D.
Other TCT 2019 News:
Positive Safety, Efficacy Data Reported on AccuCinch Heart Failure Device
EchoPixel Introduces 3-D Holographic Intraoperative Software
New Research on Tempo Temporary Pacing Lead to Be Featured at TCT 2019
Supraflex Drug-Eluting Stent Superior to Xience in Two-Year Target Vessel Failure
For more information: www.crf.org/tct
Related Late-breaking Cardiovascular Trials:
ACC 2019 Late-breaking Presentations
Late-breaking Interventional Cardiology Presentations at SCAI 2019
American Heart Association 2018 Late-breaking Trials
VIVA 2019 Late-breaking Clinical Trials
#TCT2019
October 31, 2025 
